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Multi-ancestry genetic analysis of gene regulation in coronary arteries prioritizes disease risk loci.
Hodonsky CJ, Turner AW, Khan MD, Barrientos NB, Methorst R, Ma L, Lopez NG, Mosquera JV, Auguste G, Farber E, Ma WF, Wong D, Onengut-Gumuscu S, Kavousi M, Peyser PA, van der Laan SW, Leeper NJ, Kovacic JC, Björkegren JLM, Miller CL. Hodonsky CJ, et al. Among authors: miller cl. Cell Genom. 2024 Jan 10;4(1):100465. doi: 10.1016/j.xgen.2023.100465. Epub 2023 Dec 15. Cell Genom. 2024. PMID: 38190101 Free PMC article.
Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.
Leeper NJ, Raiesdana A, Kojima Y, Kundu RK, Cheng H, Maegdefessel L, Toh R, Ahn GO, Ali ZA, Anderson DR, Miller CL, Roberts SC, Spin JM, de Almeida PE, Wu JC, Xu B, Cheng K, Quertermous M, Kundu S, Kortekaas KE, Berzin E, Downing KP, Dalman RL, Tsao PS, Schadt EE, Owens GK, Quertermous T. Leeper NJ, et al. Among authors: miller cl. Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):e1-e10. doi: 10.1161/ATVBAHA.112.300399. Epub 2012 Nov 15. Arterioscler Thromb Vasc Biol. 2013. PMID: 23162013 Free PMC article.
Disease-related growth factor and embryonic signaling pathways modulate an enhancer of TCF21 expression at the 6q23.2 coronary heart disease locus.
Miller CL, Anderson DR, Kundu RK, Raiesdana A, Nürnberg ST, Diaz R, Cheng K, Leeper NJ, Chen CH, Chang IS, Schadt EE, Hsiung CA, Assimes TL, Quertermous T. Miller CL, et al. PLoS Genet. 2013;9(7):e1003652. doi: 10.1371/journal.pgen.1003652. Epub 2013 Jul 18. PLoS Genet. 2013. PMID: 23874238 Free PMC article.
Genetic Regulatory Mechanisms of Smooth Muscle Cells Map to Coronary Artery Disease Risk Loci.
Liu B, Pjanic M, Wang T, Nguyen T, Gloudemans M, Rao A, Castano VG, Nurnberg S, Rader DJ, Elwyn S, Ingelsson E, Montgomery SB, Miller CL, Quertermous T. Liu B, et al. Among authors: miller cl. Am J Hum Genet. 2018 Sep 6;103(3):377-388. doi: 10.1016/j.ajhg.2018.08.001. Epub 2018 Aug 23. Am J Hum Genet. 2018. PMID: 30146127 Free PMC article.
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus.
Nanda V, Wang T, Pjanic M, Liu B, Nguyen T, Matic LP, Hedin U, Koplev S, Ma L, Franzén O, Ruusalepp A, Schadt EE, Björkegren JLM, Montgomery SB, Snyder MP, Quertermous T, Leeper NJ, Miller CL. Nanda V, et al. Among authors: miller cl. PLoS Genet. 2018 Nov 16;14(11):e1007755. doi: 10.1371/journal.pgen.1007755. eCollection 2018 Nov. PLoS Genet. 2018. PMID: 30444878 Free PMC article.
537 results