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Anti-Ebola virus mAb 3A6 with unprecedented potency protects highly viremic animals from fatal outcome and physically lifts its glycoprotein target from the virion membrane.
Saphire E, Salie ZL, Ke Z, Halfmann P, DeWald LE, McArdle S, Grinyo A, Davidson E, Schendel S, Hariharan C, Norris M, Yu X, Chennareddy C, Xiong X, Heinrich M, Holbrook M, Doranz B, Crozier I, Hastie K, Kawaoka Y, Branco L, Kuhn J, Briggs J, Worwa G, Davis C, Ahmed R. Saphire E, et al. Among authors: dewald le. Res Sq [Preprint]. 2023 Dec 22:rs.3.rs-3722563. doi: 10.21203/rs.3.rs-3722563/v1. Res Sq. 2023. PMID: 38196595 Free PMC article. Preprint.
Erratum for Herring et al., "Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs".
Herring S, Oda JM, Wagoner J, Kirchmeier D, O'Connor A, Nelson EA, Huang Q, Liang Y, DeWald LE, Johansen LM, Glass PJ, Olinger GG, Ianevski A, Aittokallio T, Paine MF, Fink SL, White JM, Polyak SJ. Herring S, et al. Among authors: dewald le. Antimicrob Agents Chemother. 2021 May 18;65(6):e00653-21. doi: 10.1128/AAC.00653-21. Print 2021 May 18. Antimicrob Agents Chemother. 2021. PMID: 34006613 Free PMC article. No abstract available.
Formulation, Stability, Pharmacokinetic, and Modeling Studies for Tests of Synergistic Combinations of Orally Available Approved Drugs against Ebola Virus In Vivo.
Finch CL, Dyall J, Xu S, Nelson EA, Postnikova E, Liang JY, Zhou H, DeWald LE, Thomas CJ, Wang A, Xu X, Hughes E, Morris PJ, Mirsalis JC, Nguyen LH, Arolfo MP, Koci B, Holbrook MR, Hensley LE, Jahrling PB, Schmaljohn C, Johansen LM, Olinger GG, Schiffer JT, White JM. Finch CL, et al. Among authors: dewald le. Microorganisms. 2021 Mar 10;9(3):566. doi: 10.3390/microorganisms9030566. Microorganisms. 2021. PMID: 33801811 Free PMC article.
Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs.
Herring S, Oda JM, Wagoner J, Kirchmeier D, O'Connor A, Nelson EA, Huang Q, Liang Y, DeWald LE, Johansen LM, Glass PJ, Olinger GG, Ianevski A, Aittokallio T, Paine MF, Fink SL, White JM, Polyak SJ. Herring S, et al. Among authors: dewald le. Antimicrob Agents Chemother. 2021 Mar 18;65(4):e01146-20. doi: 10.1128/AAC.01146-20. Print 2021 Mar 18. Antimicrob Agents Chemother. 2021. PMID: 33468464 Free PMC article.
In Vivo Activity of Amodiaquine against Ebola Virus Infection.
DeWald LE, Johnson JC, Gerhardt DM, Torzewski LM, Postnikova E, Honko AN, Janosko K, Huzella L, Dowling WE, Eakin AE, Osborn BL, Gahagen J, Tang L, Green CE, Mirsalis JC, Holbrook MR, Jahrling PB, Dyall J, Hensley LE. DeWald LE, et al. Sci Rep. 2019 Dec 27;9(1):20199. doi: 10.1038/s41598-019-56481-0. Sci Rep. 2019. PMID: 31882748 Free PMC article.
Inhibition of Ebola Virus by a Molecularly Engineered Banana Lectin.
Covés-Datson EM, Dyall J, DeWald LE, King SR, Dube D, Legendre M, Nelson E, Drews KC, Gross R, Gerhardt DM, Torzewski L, Postnikova E, Liang JY, Ban B, Shetty J, Hensley LE, Jahrling PB, Olinger GG Jr, White JM, Markovitz DM. Covés-Datson EM, et al. Among authors: dewald le. PLoS Negl Trop Dis. 2019 Jul 29;13(7):e0007595. doi: 10.1371/journal.pntd.0007595. eCollection 2019 Jul. PLoS Negl Trop Dis. 2019. PMID: 31356611 Free PMC article.
Persistence of Lassa Virus Associated With Severe Systemic Arteritis in Convalescing Guinea Pigs (Cavia porcellus).
Liu DX, Perry DL, DeWald LE, Cai Y, Hagen KR, Cooper TK, Huzella LM, Hart R, Bonilla A, Bernbaum JG, Janosko KB, Adams R, Johnson RF, Kuhn JH, Schnell MJ, Crozier I, Jahrling PB, de la Torre JC. Liu DX, et al. Among authors: dewald le. J Infect Dis. 2019 May 5;219(11):1818-1822. doi: 10.1093/infdis/jiy641. J Infect Dis. 2019. PMID: 30517671 Free PMC article.
22 results