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Safety, tolerability, and effect of a single aural dose of Dornase alfa at the time of ventilation tube surgery for otitis media: A Phase 1b double randomized control trial.
Thornton RB, Jeffares S, Seppanen E, Jacoby P, Kirkham LS, Bennett H, Coates HL, Vijayasekaran S, Brennan-Jones CG, Richmond PC. Thornton RB, et al. Among authors: seppanen e. Int J Pediatr Otorhinolaryngol. 2024 Feb;177:111832. doi: 10.1016/j.ijporl.2023.111832. Epub 2023 Dec 21. Int J Pediatr Otorhinolaryngol. 2024. PMID: 38215661 Free article. Clinical Trial.
High concentrations of middle ear antimicrobial peptides and proteins and proinflammatory cytokines are associated with detection of middle ear pathogens in children with recurrent acute otitis media.
Seppanen EJ, Thornton RB, Corscadden KJ, Granland CM, Hibbert J, Fuery A, Wiertsema SP, Vijayasekaran S, Coates HL, Jacoby P, Currie A, Richmond PC, Kirkham LS. Seppanen EJ, et al. PLoS One. 2019 Dec 26;14(12):e0227080. doi: 10.1371/journal.pone.0227080. eCollection 2019. PLoS One. 2019. PMID: 31877198 Free PMC article.
PCV10 elicits Protein D IgG responses in Papua New Guinean children but has no impact on NTHi carriage in the first two years of life.
Rahman T, de Gier C, Orami T, Seppanen EJ, Granland CM, Francis JP, Michael A, Yoannes M, Corscadden KJ, Ford RL, Martinovich KM, Jacoby P, van den Biggelaar AHJ, Lehmann D, Richmond PC, Pomat WS, Thornton RB, Kirkham LS. Rahman T, et al. Among authors: seppanen ej. Vaccine. 2021 Jun 11;39(26):3486-3492. doi: 10.1016/j.vaccine.2021.05.022. Epub 2021 May 21. Vaccine. 2021. PMID: 34024658 Free article.
Differences in Pneumococcal and Haemophilus influenzae Natural Antibody Development in Papua New Guinean Children in the First Year of Life.
Martinovich KM, Rahman T, de Gier C, Seppanen EJ, Orami T, Granland CM, Francis J, Yoannes M, Corscadden KJ, Ford R, Jacoby P, van den Biggelaar AHJ, Bakaletz LO, Cripps AW, Lehmann D, Richmond PC, Pomat WS, Kirkham LS, Thornton RB. Martinovich KM, et al. Among authors: seppanen ej. Front Immunol. 2021 Aug 10;12:725244. doi: 10.3389/fimmu.2021.725244. eCollection 2021. Front Immunol. 2021. PMID: 34447389 Free PMC article. Clinical Trial.
Sleep Disordered Breathing and Recurrent Tonsillitis Are Associated With Polymicrobial Bacterial Biofilm Infections Suggesting a Role for Anti-Biofilm Therapies.
Mateus T, Seppanen EJ, de Gier C, Clark S, Coates H, Vijayasekaran S, Prosser K, Wiertsema SP, Fuery A, Kirkham LS, Richmond PC, Thornton RB. Mateus T, et al. Among authors: seppanen ej. Front Cell Infect Microbiol. 2022 Feb 28;12:831887. doi: 10.3389/fcimb.2022.831887. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35295756 Free PMC article.
Australian Aboriginal Otitis-Prone Children Produce High-Quality Serum IgG to Putative Nontypeable Haemophilus influenzae Vaccine Antigens at Lower Titres Compared to Non-Aboriginal Children.
Clark SL, Seppanen EJ, Kirkham LS, Novotny LA, Bakaletz LO, Cripps AW, Corscadden K, Coates H, Vijayasekaran S, Richmond PC, Thornton RB. Clark SL, et al. Among authors: seppanen ej. Front Cell Infect Microbiol. 2022 Apr 7;12:767083. doi: 10.3389/fcimb.2022.767083. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35463651 Free PMC article.
Evidence of maternal transfer of antigen-specific antibodies in serum and breast milk to infants at high-risk of S. pneumoniae and H. influenzae disease.
Martinovich KM, Seppanen EJ, Bleakley AS, Clark SL, Andrews RM, Richmond PC, Binks MJ, Thornton RB, Kirkham LS. Martinovich KM, et al. Among authors: seppanen ej. Front Immunol. 2022 Sep 21;13:1005344. doi: 10.3389/fimmu.2022.1005344. eCollection 2022. Front Immunol. 2022. PMID: 36211411 Free PMC article. Clinical Trial.
37 results