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Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response.
McNamara HA, Idris AH, Sutton HJ, Vistein R, Flynn BJ, Cai Y, Wiehe K, Lyke KE, Chatterjee D, Kc N, Chakravarty S, Lee Sim BK, Hoffman SL, Bonsignori M, Seder RA, Cockburn IA. McNamara HA, et al. Among authors: idris ah. Cell Host Microbe. 2020 Oct 7;28(4):572-585.e7. doi: 10.1016/j.chom.2020.07.001. Epub 2020 Jul 21. Cell Host Microbe. 2020. PMID: 32697938 Free article.
A Potent Anti-Malarial Human Monoclonal Antibody Targets Circumsporozoite Protein Minor Repeats and Neutralizes Sporozoites in the Liver.
Wang LT, Pereira LS, Flores-Garcia Y, O'Connor J, Flynn BJ, Schön A, Hurlburt NK, Dillon M, Yang ASP, Fabra-García A, Idris AH, Mayer BT, Gerber MW, Gottardo R, Mason RD, Cavett N, Ballard RB, Kisalu NK, Molina-Cruz A, Nelson J, Vistein R, Barillas-Mury C, Amino R, Baker D, King NP, Sauerwein RW, Pancera M, Cockburn IA, Zavala F, Francica JR, Seder RA. Wang LT, et al. Among authors: idris ah. Immunity. 2020 Oct 13;53(4):733-744.e8. doi: 10.1016/j.immuni.2020.08.014. Epub 2020 Sep 17. Immunity. 2020. PMID: 32946741 Free PMC article. Clinical Trial.
Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans.
Sutton HJ, Aye R, Idris AH, Vistein R, Nduati E, Kai O, Mwacharo J, Li X, Gao X, Andrews TD, Koutsakos M, Nguyen THO, Nekrasov M, Milburn P, Eltahla A, Berry AA, Kc N, Chakravarty S, Sim BKL, Wheatley AK, Kent SJ, Hoffman SL, Lyke KE, Bejon P, Luciani F, Kedzierska K, Seder RA, Ndungu FM, Cockburn IA. Sutton HJ, et al. Among authors: idris ah. Cell Rep. 2021 Feb 9;34(6):108684. doi: 10.1016/j.celrep.2020.108684. Cell Rep. 2021. PMID: 33567273 Free PMC article. Clinical Trial.
Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Kratochvil S, Shen CH, Lin YC, Xu K, Nair U, Da Silva Pereira L, Tripathi P, Arnold J, Chuang GY, Melzi E, Schön A, Zhang B, Dillon M, Bonilla B, Flynn BJ, Kirsch KH, Kisalu NK, Kiyuka PK, Liu T, Ou L, Pancera M, Rawi R, Reveiz M, Seignon K, Wang LT, Waring MT, Warner J, Yang Y, Francica JR, Idris AH, Seder RA, Kwong PD, Batista FD. Kratochvil S, et al. Among authors: idris ah. Immunity. 2021 Dec 14;54(12):2859-2876.e7. doi: 10.1016/j.immuni.2021.10.017. Epub 2021 Nov 16. Immunity. 2021. PMID: 34788599 Free PMC article.
Protective effects of combining monoclonal antibodies and vaccines against the Plasmodium falciparum circumsporozoite protein.
Wang LT, Pereira LS, Kiyuka PK, Schön A, Kisalu NK, Vistein R, Dillon M, Bonilla BG, Molina-Cruz A, Barillas-Mury C, Tan J, Idris AH, Francica JR, Seder RA. Wang LT, et al. Among authors: idris ah. PLoS Pathog. 2021 Dec 6;17(12):e1010133. doi: 10.1371/journal.ppat.1010133. eCollection 2021 Dec. PLoS Pathog. 2021. PMID: 34871332 Free PMC article.
Functional human IgA targets a conserved site on malaria sporozoites.
Tan J, Cho H, Pholcharee T, Pereira LS, Doumbo S, Doumtabe D, Flynn BJ, Schön A, Kanatani S, Aylor SO, Oyen D, Vistein R, Wang L, Dillon M, Skinner J, Peterson M, Li S, Idris AH, Molina-Cruz A, Zhao M, Olano LR, Lee PJ, Roth A, Sinnis P, Barillas-Mury C, Kayentao K, Ongoiba A, Francica JR, Traore B, Wilson IA, Seder RA, Crompton PD. Tan J, et al. Among authors: idris ah. Sci Transl Med. 2021 Jun 23;13(599):eabg2344. doi: 10.1126/scitranslmed.abg2344. Sci Transl Med. 2021. PMID: 34162751 Free PMC article.
183 results