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Kaposi's sarcoma herpesvirus latency-associated nuclear antigen broadly regulates viral gene expression and is essential for lytic infection.
Li S, Wang M, Van Sciver N, Szymula A, Tumuluri VS, George A, Ramachandran A, Raina K, Costa CN, Zhao B, Kazemian M, Simas JP, Kaye KM. Li S, et al. Among authors: kaye km. PLoS Pathog. 2024 Jan 17;20(1):e1011907. doi: 10.1371/journal.ppat.1011907. eCollection 2024 Jan. PLoS Pathog. 2024. PMID: 38232124 Free PMC article.
KSHV LANA acetylation-selective acidic domain reader sequence mediates virus persistence.
Juillard F, de Miranda MP, Li S, Franco A, Seixas AF, Liu B, Álvarez ÁL, Tan M, Szymula A, Kaye KM, Simas JP. Juillard F, et al. Among authors: kaye km. Proc Natl Acad Sci U S A. 2020 Sep 8;117(36):22443-22451. doi: 10.1073/pnas.2004809117. Epub 2020 Aug 20. Proc Natl Acad Sci U S A. 2020. PMID: 32820070 Free PMC article.
MLL1 is regulated by KSHV LANA and is important for virus latency.
Tan M, Li S, Juillard F, Chitas R, Custódio TF, Xue H, Szymula A, Sun Q, Liu B, Álvarez ÁL, Chen S, Huang J, Simas JP, McVey CE, Kaye KM. Tan M, et al. Among authors: kaye km. Nucleic Acids Res. 2021 Dec 16;49(22):12895-12911. doi: 10.1093/nar/gkab1094. Nucleic Acids Res. 2021. PMID: 34850113 Free PMC article.
Macrophages drive KSHV B cell latency.
Szymula A, Samayoa-Reyes G, Ogolla S, Liu B, Li S, George A, Van Sciver N, Rochford R, Simas JP, Kaye KM. Szymula A, et al. Among authors: kaye km. Cell Rep. 2023 Jul 25;42(7):112767. doi: 10.1016/j.celrep.2023.112767. Epub 2023 Jul 12. Cell Rep. 2023. PMID: 37440412 Free PMC article.
Kaposi's sarcoma herpesvirus exploits the DNA damage response to circularize its genome.
Li S, Liu B, Tan M, Juillard F, Szymula A, Álvarez ÁL, Van Sciver N, George A, Ramachandran A, Raina K, Tumuluri VS, Costa CN, Simas JP, Kaye KM. Li S, et al. Among authors: kaye km. Nucleic Acids Res. 2024 Feb 28;52(4):1814-1829. doi: 10.1093/nar/gkad1224. Nucleic Acids Res. 2024. PMID: 38180827 Free PMC article.
78 results