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Longitudinal single cell atlas identifies complex temporal relationship between type I interferon response and COVID-19 severity.
Lin QXX, Rajagopalan D, Gamage AM, Tan LM, Venkatesh PN, Chan WOY, Kumar D, Agrawal R, Chen Y, Fong SW, Singh A, Sun LJ, Tan SY, Chai LYA, Somani J, Lee B, Renia L, Ng LFP, Ramanathan K, Wang LF, Young B, Lye D, Singhal A, Prabhakar S. Lin QXX, et al. Among authors: chai lya. Nat Commun. 2024 Jan 18;15(1):567. doi: 10.1038/s41467-023-44524-0. Nat Commun. 2024. PMID: 38238298 Free PMC article.
Histoplasmosis presenting with Sweet's syndrome.
Yan G, Tan KB, Chandran NS, Chai L, Chew KL, Somani J, Tambyah PA. Yan G, et al. Clin Microbiol Infect. 2020 Jun;26(6):795-796. doi: 10.1016/j.cmi.2020.01.031. Epub 2020 Feb 6. Clin Microbiol Infect. 2020. PMID: 32035234 Free article. No abstract available.
When to Test for Anti-Interferon-γ Autoantibody?
Loh KM, Zhong Y, Lin L, Chan M, Cherng BPZ, Yew HS, Sun H, Lee Dickens BS, Lye DCB, Huang CH, Khoo AL, Chai LYA. Loh KM, et al. Among authors: chai lya. Clin Infect Dis. 2020 Oct 23;71(7):e199. doi: 10.1093/cid/ciaa129. Clin Infect Dis. 2020. PMID: 32052830 No abstract available.
Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients.
Poh CM, Carissimo G, Wang B, Amrun SN, Lee CY, Chee RS, Fong SW, Yeo NK, Lee WH, Torres-Ruesta A, Leo YS, Chen MI, Tan SY, Chai LYA, Kalimuddin S, Kheng SSG, Thien SY, Young BE, Lye DC, Hanson BJ, Wang CI, Renia L, Ng LFP. Poh CM, et al. Among authors: chai lya. Nat Commun. 2020 Jun 1;11(1):2806. doi: 10.1038/s41467-020-16638-2. Nat Commun. 2020. PMID: 32483236 Free PMC article.
Responding to COVID-19: how an academic infectious diseases division mobilized in Singapore.
Archuleta S, Cross G, Somani J, Lum L, Santosa A, Alagha RA, Allen DM, Ang A, Beh D, Chai L, Chan SM, Lim SM, Olszyna DP, Ong C, Oon J, Salada BMA, Smitasin N, Sun L, Tambyah PA, Tham SM, Yan G, Yee CH, Dan YY, Jureen R, Tee N, Mahadevan M, Yau YW, Quek SC, Liu EH, Sin C, Bagdasarian N, Fisher DA. Archuleta S, et al. BMC Med. 2020 Jun 8;18(1):179. doi: 10.1186/s12916-020-01641-7. BMC Med. 2020. PMID: 32507112 Free PMC article.
Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study.
Young BE, Fong SW, Chan YH, Mak TM, Ang LW, Anderson DE, Lee CY, Amrun SN, Lee B, Goh YS, Su YCF, Wei WE, Kalimuddin S, Chai LYA, Pada S, Tan SY, Sun L, Parthasarathy P, Chen YYC, Barkham T, Lin RTP, Maurer-Stroh S, Leo YS, Wang LF, Renia L, Lee VJ, Smith GJD, Lye DC, Ng LFP. Young BE, et al. Among authors: chai lya. Lancet. 2020 Aug 29;396(10251):603-611. doi: 10.1016/S0140-6736(20)31757-8. Epub 2020 Aug 18. Lancet. 2020. PMID: 32822564 Free PMC article.
Viral Dynamics and Immune Correlates of Coronavirus Disease 2019 (COVID-19) Severity.
Young BE, Ong SWX, Ng LFP, Anderson DE, Chia WN, Chia PY, Ang LW, Mak TM, Kalimuddin S, Chai LYA, Pada S, Tan SY, Sun L, Parthasarathy P, Fong SW, Chan YH, Tan CW, Lee B, Rötzschke O, Ding Y, Tambyah P, Low JGH, Cui L, Barkham T, Lin RTP, Leo YS, Renia L, Wang LF, Lye DC; Singapore 2019 Novel Coronavirus Outbreak Research Team. Young BE, et al. Among authors: chai lya. Clin Infect Dis. 2021 Nov 2;73(9):e2932-e2942. doi: 10.1093/cid/ciaa1280. Clin Infect Dis. 2021. PMID: 32856707 Free PMC article.
Clinical features and predictors of severity in COVID-19 patients with critical illness in Singapore.
Puah SH, Young BE, Chia PY, Ho VK, Loh J, Gokhale RS, Tan SY, Sewa DW, Kalimuddin S, Tan CK, Pada SKMS, Cove ME, Chai LYA, Parthasarathy P, Ho BCH, Ng JJ, Ling LM, Abisheganaden JA, Lee VJM, Tan CH, Lin RTP, Leo YS, Lye DC, Yeo TW; Singapore 2019 novel coronavirus outbreak research team. Puah SH, et al. Among authors: chai lya. Sci Rep. 2021 Apr 5;11(1):7477. doi: 10.1038/s41598-021-81377-3. Sci Rep. 2021. PMID: 33820944 Free PMC article.
Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort study.
Chia PY, Ong SWX, Chiew CJ, Ang LW, Chavatte JM, Mak TM, Cui L, Kalimuddin S, Chia WN, Tan CW, Chai LYA, Tan SY, Zheng S, Lin RTP, Wang L, Leo YS, Lee VJ, Lye DC, Young BE. Chia PY, et al. Among authors: chai lya. Clin Microbiol Infect. 2022 Apr;28(4):612.e1-612.e7. doi: 10.1016/j.cmi.2021.11.010. Epub 2021 Nov 23. Clin Microbiol Infect. 2022. PMID: 34826623 Free PMC article.
95 results