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Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge.
Grunst MW, Gil HM, Grandea AG 3rd, Snow BJ, Andrabi R, Nedellec R, Burton I, Clark NM, Janaka SK, Keles NK, Moriarty RV, Weiler AM, Capuano S 3rd, Fennessey CM, Friedrich TC, O'Connor SL, O'Connor DH, Broman AT, Keele BF, Lifson JD, Hangartner L, Burton DR, Evans DT. Grunst MW, et al. Among authors: burton dr. PLoS Pathog. 2024 Jan 22;20(1):e1011819. doi: 10.1371/journal.ppat.1011819. eCollection 2024 Jan. PLoS Pathog. 2024. PMID: 38252675 Free PMC article.
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection.
Zhou P, Yuan M, Song G, Beutler N, Shaabani N, Huang D, He WT, Zhu X, Callaghan S, Yong P, Anzanello F, Peng L, Ricketts J, Parren M, Garcia E, Rawlings SA, Smith DM, Nemazee D, Teijaro JR, Rogers TF, Wilson IA, Burton DR, Andrabi R. Zhou P, et al. Among authors: burton dr. bioRxiv [Preprint]. 2022 Jan 21:2021.03.30.437769. doi: 10.1101/2021.03.30.437769. bioRxiv. 2022. PMID: 33821273 Free PMC article. Updated. Preprint.
Targeted isolation of panels of diverse human protective broadly neutralizing antibodies against SARS-like viruses.
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schäfer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, Anzanello F, Capozzola T, Parren M, Garcia E, Rawlings SA, Smith DM, Wilson IA, Safonova Y, Ward AB, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R. He WT, et al. Among authors: burton dr. bioRxiv [Preprint]. 2022 Feb 8:2021.09.08.459480. doi: 10.1101/2021.09.08.459480. bioRxiv. 2022. PMID: 35169804 Free PMC article. Updated. Preprint.
A broad and potent neutralization epitope in SARS-related coronaviruses.
Yuan M, Zhu X, He WT, Zhou P, Kaku CI, Capozzola T, Zhu CY, Yu X, Liu H, Yu W, Hua Y, Tien H, Peng L, Song G, Cottrell CA, Schief WR, Nemazee D, Walker LM, Andrabi R, Burton DR, Wilson IA. Yuan M, et al. Among authors: burton dr. bioRxiv [Preprint]. 2022 Mar 14:2022.03.13.484037. doi: 10.1101/2022.03.13.484037. bioRxiv. 2022. PMID: 35313576 Free PMC article. Updated. Preprint.
A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike.
Dadonaite B, Crawford KHD, Radford CE, Farrell AG, Yu TC, Hannon WW, Zhou P, Andrabi R, Burton DR, Liu L, Ho DD, Neher RA, Bloom JD. Dadonaite B, et al. Among authors: burton dr. bioRxiv [Preprint]. 2022 Oct 13:2022.10.13.512056. doi: 10.1101/2022.10.13.512056. bioRxiv. 2022. PMID: 36263061 Free PMC article. Updated. Preprint.
Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes.
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B. Hurtado J, et al. Among authors: burton dr. bioRxiv [Preprint]. 2023 Mar 31:2023.03.28.534602. doi: 10.1101/2023.03.28.534602. bioRxiv. 2023. PMID: 37034676 Free PMC article. Preprint.
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease.
Zhou P, Song G, He WT, Beutler N, Tse LV, Martinez DR, Schäfer A, Anzanello F, Yong P, Peng L, Dueker K, Musharrafieh R, Callaghan S, Capozzola T, Yuan M, Liu H, Limbo O, Parren M, Garcia E, Rawlings SA, Smith DM, Nemazee D, Jardine JG, Wilson IA, Safonova Y, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R. Zhou P, et al. Among authors: burton dr. bioRxiv [Preprint]. 2022 Mar 7:2022.03.04.479488. doi: 10.1101/2022.03.04.479488. bioRxiv. 2022. PMID: 35291291 Free PMC article. Updated. Preprint.
Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift.
Song G, Yuan M, Liu H, Capozzola T, Lin RN, Torres JL, He WT, Musharrafieh R, Dueker K, Zhou P, Callaghan S, Mishra N, Yong P, Anzanello F, Avillion G, Vo AL, Li X, Makhdoomi M, Feng Z, Zhu X, Peng L, Nemazee D, Safonova Y, Briney B, Ward AB, Burton DR, Wilson IA, Andrabi R. Song G, et al. Among authors: burton dr. bioRxiv [Preprint]. 2023 Apr 27:2023.04.26.538488. doi: 10.1101/2023.04.26.538488. bioRxiv. 2023. PMID: 37162858 Free PMC article. Preprint.
660 results