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Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge.
Grunst MW, Gil HM, Grandea AG 3rd, Snow BJ, Andrabi R, Nedellec R, Burton I, Clark NM, Janaka SK, Keles NK, Moriarty RV, Weiler AM, Capuano S 3rd, Fennessey CM, Friedrich TC, O'Connor SL, O'Connor DH, Broman AT, Keele BF, Lifson JD, Hangartner L, Burton DR, Evans DT. Grunst MW, et al. Among authors: lifson jd. PLoS Pathog. 2024 Jan 22;20(1):e1011819. doi: 10.1371/journal.ppat.1011819. eCollection 2024 Jan. PLoS Pathog. 2024. PMID: 38252675 Free PMC article.
Lymphoid tissues contribute to viral clonotypes present in plasma at early post-ATI in SIV-infected rhesus macaques.
Solis-Leal A, Boby N, Mallick S, Cheng Y, Wu F, De La Torre G, Dufour J, Alvarez X, Shivanna V, Liu Y, Fennessey CM, Lifson JD, Li Q, Keele BF, Ling B. Solis-Leal A, et al. Among authors: lifson jd. bioRxiv [Preprint]. 2023 May 30:2023.05.30.542512. doi: 10.1101/2023.05.30.542512. bioRxiv. 2023. PMID: 37398418 Free PMC article. Updated. Preprint.
CD4 T cell Responses in the CNS during SIV infection.
Elizaldi SR, Verma A, Ma ZM, Ott S, Rajasundaram D, Cottrell ML, Kashuba ADM, Ambrose Z, Lifson JD, Morrison JH, Iyer SS. Elizaldi SR, et al. Among authors: lifson jd. bioRxiv [Preprint]. 2023 Aug 25:2023.08.24.554055. doi: 10.1101/2023.08.24.554055. bioRxiv. 2023. PMID: 37662237 Free PMC article. Updated. Preprint.
The Impact of SIV-Induced Immunodeficiency on Clinical Manifestation, Immune Response, and Viral Dynamics in SARS-CoV-2 Coinfection.
Melton A, Rowe LA, Penney T, Krzykwa C, Goff K, Scheuermann S, Melton HJ, Williams K, Golden N, Green KM, Smith B, Russell-Lodrigue K, Dufour JP, Doyle-Meyers LA, Schiro F, Aye PP, Lifson JD, Beddingfield BJ, Blair RV, Bohm RP, Kolls JK, Rappaport J, Hoxie JA, Maness NJ. Melton A, et al. Among authors: lifson jd. bioRxiv [Preprint]. 2023 Nov 16:2023.11.15.567132. doi: 10.1101/2023.11.15.567132. bioRxiv. 2023. PMID: 38014096 Free PMC article. Preprint.
SIV clearance from neonatal macaques following transient CCR5 depletion.
Deere JD, Merriam D, Leggat KM, Chang WW, Méndez-Lagares G, Kieu H, Dutra J, Fontaine J, Lu W, Chin N, Chen C, Tran BC, Salinas J, Miller CN, Deeks SG, Lifson JD, Engelman K, Magnani D, Reimann K, Stevenson M, Hartigan-O'Connor DJ. Deere JD, et al. Among authors: lifson jd. bioRxiv [Preprint]. 2023 May 1:2023.05.01.533682. doi: 10.1101/2023.05.01.533682. bioRxiv. 2023. PMID: 37205470 Free PMC article. Preprint.
Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir.
Keele BF, Okoye AA, Fennessey CM, Varco-Merth B, Immonen TT, Kose E, Conchas A, Pinkevych M, Lipkey L, Newman L, Macairan A, Bosche M, Bosche WJ, Berkemeier B, Fast R, Hull M, Oswald K, Shoemaker R, Silipino L, Gorelick RJ, Duell D, Marenco A, Brantley W, Smedley J, Axthelm M, Davenport MP, Lifson JD, Picker LJ. Keele BF, et al. Among authors: lifson jd. PLoS Pathog. 2024 Apr 9;20(4):e1012135. doi: 10.1371/journal.ppat.1012135. eCollection 2024 Apr. PLoS Pathog. 2024. PMID: 38593120 Free PMC article.
Lymphoid tissues contribute to plasma viral clonotypes early after antiretroviral therapy interruption in SIV-infected rhesus macaques.
Solis-Leal A, Boby N, Mallick S, Cheng Y, Wu F, De La Torre G, Dufour J, Alvarez X, Shivanna V, Liu Y, Fennessey CM, Lifson JD, Li Q, Keele BF, Ling B. Solis-Leal A, et al. Among authors: lifson jd. Sci Transl Med. 2023 Dec 13;15(726):eadi9867. doi: 10.1126/scitranslmed.adi9867. Epub 2023 Dec 13. Sci Transl Med. 2023. PMID: 38091409
Deep analysis of CD4 T cells in the rhesus CNS during SIV infection.
Elizaldi SR, Verma A, Ma ZM, Ott S, Rajasundaram D, Hawes CE, Lakshmanappa YS, Cottrell ML, Kashuba ADM, Ambrose Z, Lifson JD, Morrison JH, Iyer SS. Elizaldi SR, et al. Among authors: lifson jd. PLoS Pathog. 2023 Dec 7;19(12):e1011844. doi: 10.1371/journal.ppat.1011844. eCollection 2023 Dec. PLoS Pathog. 2023. PMID: 38060615 Free PMC article.
424 results