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Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge.
Grunst MW, Gil HM, Grandea AG 3rd, Snow BJ, Andrabi R, Nedellec R, Burton I, Clark NM, Janaka SK, Keles NK, Moriarty RV, Weiler AM, Capuano S 3rd, Fennessey CM, Friedrich TC, O'Connor SL, O'Connor DH, Broman AT, Keele BF, Lifson JD, Hangartner L, Burton DR, Evans DT. Grunst MW, et al. Among authors: weiler am. PLoS Pathog. 2024 Jan 22;20(1):e1011819. doi: 10.1371/journal.ppat.1011819. eCollection 2024 Jan. PLoS Pathog. 2024. PMID: 38252675 Free PMC article.
CD8+ cells and small viral reservoirs facilitate post-ART control of SIV replication in M3+ Mauritian cynomolgus macaques initiated on ART two weeks post-infection.
Harwood OE, Matschke LM, Moriarty RV, Balgeman AJ, Weaver AJ, Ellis-Connell AL, Weiler AM, Winchester LC, Fletcher CV, Friedrich TC, Keele BF, O'Connor DH, Lang JD, Reynolds MR, O'Connor SL. Harwood OE, et al. Among authors: weiler am. PLoS Pathog. 2023 Sep 25;19(9):e1011676. doi: 10.1371/journal.ppat.1011676. eCollection 2023 Sep. PLoS Pathog. 2023. PMID: 37747933 Free PMC article.
Effector function does not contribute to protection from virus challenge by a highly potent HIV broadly neutralizing antibody in nonhuman primates.
Hangartner L, Beauparlant D, Rakasz E, Nedellec R, Hozé N, McKenney K, Martins MA, Seabright GE, Allen JD, Weiler AM, Friedrich TC, Regoes RR, Crispin M, Burton DR. Hangartner L, et al. Among authors: weiler am. Sci Transl Med. 2021 Mar 17;13(585):eabe3349. doi: 10.1126/scitranslmed.abe3349. Sci Transl Med. 2021. PMID: 33731434 Free PMC article.
The mucosal barrier and anti-viral immune responses can eliminate portions of the viral population during transmission and early viral growth.
Moriarty RV, Golfinos AE, Gellerup DD, Schweigert H, Mathiaparanam J, Balgeman AJ, Weiler AM, Friedrich TC, Keele BF, Davenport MP, Venturi V, O'Connor SL. Moriarty RV, et al. Among authors: weiler am. PLoS One. 2021 Dec 2;16(12):e0260010. doi: 10.1371/journal.pone.0260010. eCollection 2021. PLoS One. 2021. PMID: 34855793 Free PMC article.
Control of Simian Immunodeficiency Virus Infection in Prophylactically Vaccinated, Antiretroviral Treatment-Naive Macaques Is Required for the Most Efficacious CD8 T Cell Response during Treatment with the Interleukin-15 Superagonist N-803.
Ellis-Connell AL, Balgeman AJ, Harwood OE, Moriarty RV, Safrit JT, Weiler AM, Friedrich TC, O'Connor SL. Ellis-Connell AL, et al. Among authors: weiler am. J Virol. 2022 Oct 26;96(20):e0118522. doi: 10.1128/jvi.01185-22. Epub 2022 Oct 3. J Virol. 2022. PMID: 36190241 Free PMC article.
CD8+ cells and small viral reservoirs facilitate post-ART control of SIV in Mauritian cynomolgus macaques.
Harwood OE, Matschke LM, Moriarty RV, Balgeman AJ, Weaver AJ, Ellis-Connell AL, Weiler AM, Winchester LC, Fletcher CV, Friedrich TC, Keele BF, O'Connor DH, Lang JD, Reynolds MR, O'Connor SL. Harwood OE, et al. Among authors: weiler am. bioRxiv [Preprint]. 2023 Mar 2:2023.03.01.530655. doi: 10.1101/2023.03.01.530655. bioRxiv. 2023. PMID: 36909458 Free PMC article. Updated. Preprint.
Heterologous Protection against Asian Zika Virus Challenge in Rhesus Macaques.
Aliota MT, Dudley DM, Newman CM, Mohr EL, Gellerup DD, Breitbach ME, Buechler CR, Rasheed MN, Mohns MS, Weiler AM, Barry GL, Weisgrau KL, Eudailey JA, Rakasz EG, Vosler LJ, Post J, Capuano S 3rd, Golos TG, Permar SR, Osorio JE, Friedrich TC, O'Connor SL, O'Connor DH. Aliota MT, et al. Among authors: weiler am. PLoS Negl Trop Dis. 2016 Dec 2;10(12):e0005168. doi: 10.1371/journal.pntd.0005168. eCollection 2016 Dec. PLoS Negl Trop Dis. 2016. PMID: 27911897 Free PMC article.
Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques.
Nguyen SM, Antony KM, Dudley DM, Kohn S, Simmons HA, Wolfe B, Salamat MS, Teixeira LBC, Wiepz GJ, Thoong TH, Aliota MT, Weiler AM, Barry GL, Weisgrau KL, Vosler LJ, Mohns MS, Breitbach ME, Stewart LM, Rasheed MN, Newman CM, Graham ME, Wieben OE, Turski PA, Johnson KM, Post J, Hayes JM, Schultz-Darken N, Schotzko ML, Eudailey JA, Permar SR, Rakasz EG, Mohr EL, Capuano S 3rd, Tarantal AF, Osorio JE, O'Connor SL, Friedrich TC, O'Connor DH, Golos TG. Nguyen SM, et al. Among authors: weiler am. PLoS Pathog. 2017 May 25;13(5):e1006378. doi: 10.1371/journal.ppat.1006378. eCollection 2017 May. PLoS Pathog. 2017. PMID: 28542585 Free PMC article.
Molecularly barcoded Zika virus libraries to probe in vivo evolutionary dynamics.
Aliota MT, Dudley DM, Newman CM, Weger-Lucarelli J, Stewart LM, Koenig MR, Breitbach ME, Weiler AM, Semler MR, Barry GL, Zarbock KR, Haj AK, Moriarty RV, Mohns MS, Mohr EL, Venturi V, Schultz-Darken N, Peterson E, Newton W, Schotzko ML, Simmons HA, Mejia A, Hayes JM, Capuano S 3rd, Davenport MP, Friedrich TC, Ebel GD, O'Connor SL, O'Connor DH. Aliota MT, et al. Among authors: weiler am. PLoS Pathog. 2018 Mar 28;14(3):e1006964. doi: 10.1371/journal.ppat.1006964. eCollection 2018 Mar. PLoS Pathog. 2018. PMID: 29590202 Free PMC article.
67 results