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Bile Acid Metabolism Mediates Cholesterol Homeostasis and Promotes Tumorigenesis in Clear Cell Renal Cell Carcinoma.
Riscal R, Gardner SM, Coffey NJ, Carens M, Mesaros C, Xu JP, Xue Y, Davis L, Demczyszyn S, Vogt A, Olia A, Finan JM, Godfrey J, Schultz DC, Blair IA, Keith B, Marmorstein R, Skuli N, Simon MC. Riscal R, et al. Among authors: coffey nj. Cancer Res. 2024 May 15;84(10):1570-1582. doi: 10.1158/0008-5472.CAN-23-0821. Cancer Res. 2024. PMID: 38417134
Cholesterol as a modulator of cannabinoid receptor CB2 signaling.
Yeliseev A, Iyer MR, Joseph TT, Coffey NJ, Cinar R, Zoubak L, Kunos G, Gawrisch K. Yeliseev A, et al. Among authors: coffey nj. Sci Rep. 2021 Feb 12;11(1):3706. doi: 10.1038/s41598-021-83245-6. Sci Rep. 2021. PMID: 33580091 Free PMC article.
Nuclear speckles regulate HIF-2α programs and correlate with patient survival in kidney cancer.
Alexander KA, Yu R, Skuli N, Coffey NJ, Nguyen S, Faunce C, Huang H, Dardani IP, Good AL, Lim J, Li C, Biddle N, Joyce EF, Raj A, Lee D, Keith B, Simon MC, Berger SL. Alexander KA, et al. Among authors: coffey nj. bioRxiv [Preprint]. 2023 Sep 16:2023.09.14.557228. doi: 10.1101/2023.09.14.557228. bioRxiv. 2023. PMID: 37745397 Free PMC article. Preprint.
Synthesis, Biological Evaluation, and Molecular Modeling Studies of 3,4-Diarylpyrazoline Series of Compounds as Potent, Nonbrain Penetrant Antagonists of Cannabinoid-1 (CB1R) Receptor with Reduced Lipophilicity.
Iyer MR, Cinar R, Wood CM, Zawatsky CN, Coffey NJ, Kim KA, Liu Z, Katz A, Abdalla J, Hassan SA, Lee YS. Iyer MR, et al. Among authors: coffey nj. J Med Chem. 2022 Feb 10;65(3):2374-2387. doi: 10.1021/acs.jmedchem.1c01836. Epub 2022 Jan 27. J Med Chem. 2022. PMID: 35084860
The key role of NLRP3 and STING in APOL1-associated podocytopathy.
Wu J, Raman A, Coffey NJ, Sheng X, Wahba J, Seasock MJ, Ma Z, Beckerman P, Laczkó D, Palmer MB, Kopp JB, Kuo JJ, Pullen SS, Boustany-Kari CM, Linkermann A, Susztak K. Wu J, et al. Among authors: coffey nj. J Clin Invest. 2021 Oct 15;131(20):e136329. doi: 10.1172/JCI136329. J Clin Invest. 2021. PMID: 34651582 Free PMC article.
CB1 R and iNOS are distinct players promoting pulmonary fibrosis in Hermansky-Pudlak syndrome.
Cinar R, Park JK, Zawatsky CN, Coffey NJ, Bodine SP, Abdalla J, Yokoyama T, Jourdan T, Jay L, Zuo MXG, O'Brien KJ, Huang J, Mackie K, Alimardanov A, Iyer MR, Gahl WA, Kunos G, Gochuico BR, Malicdan MCV. Cinar R, et al. Among authors: coffey nj. Clin Transl Med. 2021 Jul;11(7):e471. doi: 10.1002/ctm2.471. Clin Transl Med. 2021. PMID: 34323400 Free PMC article.
Functional Selectivity of a Biased Cannabinoid-1 Receptor (CB1R) Antagonist.
Liu Z, Iyer MR, Godlewski G, Jourdan T, Liu J, Coffey NJ, Zawatsky CN, Puhl HL, Wess J, Meister J, Liow JS, Innis RB, Hassan SA, Lee YS, Kunos G, Cinar R. Liu Z, et al. Among authors: coffey nj. ACS Pharmacol Transl Sci. 2021 Apr 8;4(3):1175-1187. doi: 10.1021/acsptsci.1c00048. eCollection 2021 Jun 11. ACS Pharmacol Transl Sci. 2021. PMID: 34151207 Free PMC article.
The Heterogeneity of Lipid Metabolism in Cancer.
Park JK, Coffey NJ, Limoges A, Le A. Park JK, et al. Among authors: coffey nj. Adv Exp Med Biol. 2021;1311:39-56. doi: 10.1007/978-3-030-65768-0_3. Adv Exp Med Biol. 2021. PMID: 34014533 Free PMC article.
21 results