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Impact of structural modifications of IgG antibodies on effector functions.
Damelang T, Brinkhaus M, van Osch TLJ, Schuurman J, Labrijn AF, Rispens T, Vidarsson G. Damelang T, et al. Among authors: labrijn af. Front Immunol. 2024 Jan 8;14:1304365. doi: 10.3389/fimmu.2023.1304365. eCollection 2023. Front Immunol. 2024. PMID: 38259472 Free PMC article. Review.
FcγR Binding and ADCC Activity of Human IgG Allotypes.
de Taeye SW, Bentlage AEH, Mebius MM, Meesters JI, Lissenberg-Thunnissen S, Falck D, Sénard T, Salehi N, Wuhrer M, Schuurman J, Labrijn AF, Rispens T, Vidarsson G. de Taeye SW, et al. Among authors: labrijn af. Front Immunol. 2020 May 6;11:740. doi: 10.3389/fimmu.2020.00740. eCollection 2020. Front Immunol. 2020. PMID: 32435243 Free PMC article.
The Influence of Human IgG Subclass and Allotype on Complement Activation.
Damelang T, de Taeye SW, Rentenaar R, Roya-Kouchaki K, de Boer E, Derksen NIL, van Kessel K, Lissenberg-Thunnissen S, Rooijakkers SHM, Jongerius I, Mebius MM, Schuurman J, Labrijn AF, Vidarsson G, Rispens T. Damelang T, et al. Among authors: labrijn af. J Immunol. 2023 Dec 1;211(11):1725-1735. doi: 10.4049/jimmunol.2300307. J Immunol. 2023. PMID: 37843500 Free PMC article.
When binding is enough: nonactivating antibody formats.
Labrijn AF, Aalberse RC, Schuurman J. Labrijn AF, et al. Curr Opin Immunol. 2008 Aug;20(4):479-85. doi: 10.1016/j.coi.2008.05.010. Epub 2008 Jul 9. Curr Opin Immunol. 2008. PMID: 18577454 Review.
Species-specific determinants in the IgG CH3 domain enable Fab-arm exchange by affecting the noncovalent CH3-CH3 interaction strength.
Labrijn AF, Rispens T, Meesters J, Rose RJ, den Bleker TH, Loverix S, van den Bremer ET, Neijssen J, Vink T, Lasters I, Aalberse RC, Heck AJ, van de Winkel JG, Schuurman J, Parren PW. Labrijn AF, et al. J Immunol. 2011 Sep 15;187(6):3238-46. doi: 10.4049/jimmunol.1003336. Epub 2011 Aug 12. J Immunol. 2011. PMID: 21841137
Opening the door to innovation.
Schuurman J, Graus YF, Labrijn AF, Ruuls S, Parren PW. Schuurman J, et al. Among authors: labrijn af. MAbs. 2014 Jul-Aug;6(4):812-9. doi: 10.4161/mabs.29004. Epub 2014 Apr 24. MAbs. 2014. PMID: 24784437 Free PMC article. Review.
37 results