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Hippocampus Glutathione S Reductase Potentially Confers Genetic Resilience to Cognitive Decline in the AD-BXD Mouse Population.
Saul MC, Litkowski EM, Hadad N, Dunn AR, Boas SM, Wilcox JAL, Robbins JE, Wu Y, Philip VM, Merrihew GE, Park J, De Jager PL, Bridges DE, Menon V, Bennett DA, Hohman TJ, MacCoss MJ, Kaczorowski CC. Saul MC, et al. Among authors: hohman tj. bioRxiv [Preprint]. 2024 Jan 11:2024.01.09.574219. doi: 10.1101/2024.01.09.574219. bioRxiv. 2024. PMID: 38260300 Free PMC article. Preprint.
Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer's disease.
Mahoney ER, Dumitrescu L, Moore AM, Cambronero FE, De Jager PL, Koran MEI, Petyuk VA, Robinson RAS, Goyal S, Schneider JA, Bennett DA, Jefferson AL, Hohman TJ. Mahoney ER, et al. Among authors: hohman tj. Mol Psychiatry. 2021 Mar;26(3):888-896. doi: 10.1038/s41380-019-0458-5. Epub 2019 Jul 22. Mol Psychiatry. 2021. PMID: 31332262 Free PMC article.
APOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease.
Moore AM, Mahoney E, Dumitrescu L, De Jager PL, Koran MEI, Petyuk VA, Robinson RA, Ruderfer DM, Cox NJ, Schneider JA, Bennett DA, Jefferson AL, Hohman TJ. Moore AM, et al. Among authors: hohman tj. Neurobiol Aging. 2020 Mar;87:18-25. doi: 10.1016/j.neurobiolaging.2019.10.021. Epub 2019 Nov 5. Neurobiol Aging. 2020. PMID: 31791659 Free PMC article.
Genetic variants and functional pathways associated with resilience to Alzheimer's disease.
Dumitrescu L, Mahoney ER, Mukherjee S, Lee ML, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski C, Hernandez Saucedo H, Widaman KF, Buckley R, Properzi M, Mormino E, Yang HS, Harrison T, Hedden T, Nho K, Andrews SJ, Tommet D, Hadad N, Sanders RE, Ruderfer DM, Gifford KA, Moore AM, Cambronero F, Zhong X, Raghavan NS, Vardarajan B; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer’s Disease Genetics Consortium (ADGC), A4 Study Team; Pericak-Vance MA, Farrer LA, Wang LS, Cruchaga C, Schellenberg G, Cox NJ, Haines JL, Keene CD, Saykin AJ, Larson EB, Sperling RA, Mayeux R, Bennett DA, Schneider JA, Crane PK, Jefferson AL, Hohman TJ. Dumitrescu L, et al. Among authors: hohman tj. Brain. 2020 Aug 1;143(8):2561-2575. doi: 10.1093/brain/awaa209. Brain. 2020. PMID: 32844198 Free PMC article.
Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
Ouellette AR, Neuner SM, Dumitrescu L, Anderson LC, Gatti DM, Mahoney ER, Bubier JA, Churchill G, Peters L, Huentelman MJ, Herskowitz JH, Yang HS, Smith AN, Reitz C, Kunkle BW, White CC, De Jager PL, Schneider JA, Bennett DA, Seyfried NT; Alzheimer’s Disease Genetics Consortium; Chesler EJ, Hadad N, Hohman TJ, Kaczorowski CC. Ouellette AR, et al. Among authors: hohman tj. Cell Rep. 2020 Sep 1;32(9):108091. doi: 10.1016/j.celrep.2020.108091. Cell Rep. 2020. PMID: 32877673 Free PMC article.
PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer's disease.
Nackenoff AG, Hohman TJ, Neuner SM, Akers CS, Weitzel NC, Shostak A, Ferguson SM, Mobley B, Bennett DA, Schneider JA, Jefferson AL, Kaczorowski CC, Schrag MS. Nackenoff AG, et al. Among authors: hohman tj. PLoS Genet. 2021 Apr 8;17(4):e1009406. doi: 10.1371/journal.pgen.1009406. eCollection 2021 Apr. PLoS Genet. 2021. PMID: 33830999 Free PMC article.
Translational approaches to understanding resilience to Alzheimer's disease.
Neuner SM, Telpoukhovskaia M, Menon V, O'Connell KMS, Hohman TJ, Kaczorowski CC. Neuner SM, et al. Among authors: hohman tj. Trends Neurosci. 2022 May;45(5):369-383. doi: 10.1016/j.tins.2022.02.005. Epub 2022 Mar 17. Trends Neurosci. 2022. PMID: 35307206 Free PMC article. Review.
Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.
Eissman JM, Dumitrescu L, Mahoney ER, Smith AN, Mukherjee S, Lee ML, Scollard P, Choi SE, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski CC, Hernandez Saucedo H, Widaman KF, Buckley RF, Properzi MJ, Mormino EC, Yang HS, Harrison TM, Hedden T, Nho K, Andrews SJ, Tommet D, Hadad N, Sanders RE, Ruderfer DM, Gifford KA, Zhong X, Raghavan NS, Vardarajan BN; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer’s Disease Genetics Consortium (ADGC); A4 Study Team; Pericak-Vance MA, Farrer LA, Wang LS, Cruchaga C, Schellenberg GD, Cox NJ, Haines JL, Keene CD, Saykin AJ, Larson EB, Sperling RA, Mayeux R, Cuccaro ML, Bennett DA, Schneider JA, Crane PK, Jefferson AL, Hohman TJ. Eissman JM, et al. Among authors: hohman tj. Brain. 2022 Jul 29;145(7):2541-2554. doi: 10.1093/brain/awac177. Brain. 2022. PMID: 35552371 Free PMC article.
150 results