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Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Mealka M, Sierra NA, Matteo DA, Albekioni E, Khoury R, Mai T, Conley BM, Coleman NJ, Sabo KA, Komives EA, Bobkov AA, Cooksy AL, Silletti S, Schiffer JM, Huxford T, Sohl CD. Mealka M, et al. Among authors: cooksy al. bioRxiv [Preprint]. 2024 Jan 23:2024.01.10.574970. doi: 10.1101/2024.01.10.574970. bioRxiv. 2024. PMID: 38260668 Free PMC article. Updated. Preprint.
Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Mealka M, Sierra NA, Matteo DA, Albekioni E, Khoury R, Mai T, Conley BM, Coleman NJ, Sabo KA, Komives EA, Bobkov AA, Cooksy AL, Silletti S, Schiffer JM, Huxford T, Sohl CD. Mealka M, et al. Among authors: cooksy al. Res Sq [Preprint]. 2024 Feb 23:rs.3.rs-3889456. doi: 10.21203/rs.3.rs-3889456/v1. Res Sq. 2024. PMID: 38464189 Free PMC article. Updated. Preprint.
Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Mealka M, Sierra NA, Avellaneda Matteo D, Albekioni E, Khoury R, Mai T, Conley BM, Coleman NJ, Sabo KA, Komives EA, Bobkov AA, Cooksy AL, Silletti S, Schiffer JM, Huxford T, Sohl CD. Mealka M, et al. Among authors: cooksy al. Nat Commun. 2024 May 6;15(1):3785. doi: 10.1038/s41467-024-48277-2. Nat Commun. 2024. PMID: 38710674 Free PMC article.
Enantiopure, luminescent, cyclometalated Ir(III) complexes with N-heterocyclic carbene-naphthalimide chromophore: design, vibrational circular dichroism and TD-DFT calculations.
Groué A, Montier-Sorkine E, Cheng Y, Rager MN, Jean M, Vanthuyne N, Crassous J, Lopez AC, Saavedra Moncada A, Barbieri A, Cooksy AL, Amouri H. Groué A, et al. Among authors: cooksy al. Dalton Trans. 2022 Feb 14;51(7):2750-2759. doi: 10.1039/d1dt04006e. Dalton Trans. 2022. PMID: 35080558
Si2C5H2 isomers - search algorithms versus chemical intuition.
Thirumoorthy K , Cooksy AL , Thimmakondu VS . Thirumoorthy K , et al. Among authors: cooksy al. Phys Chem Chem Phys. 2020 Mar 14;22(10):5865-5872. doi: 10.1039/c9cp06145b. Epub 2020 Feb 28. Phys Chem Chem Phys. 2020. PMID: 32108184
38 results