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Optimal trade-off control in machine learning-based library design, with application to adeno-associated virus (AAV) for gene therapy.
Zhu D, Brookes DH, Busia A, Carneiro A, Fannjiang C, Popova G, Shin D, Donohue KC, Lin LF, Miller ZM, Williams ER, Chang EF, Nowakowski TJ, Listgarten J, Schaffer DV. Zhu D, et al. Among authors: chang ef. Sci Adv. 2024 Jan 26;10(4):eadj3786. doi: 10.1126/sciadv.adj3786. Epub 2024 Jan 24. Sci Adv. 2024. PMID: 38266077 Free PMC article.
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.
Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, Shoichet B, von Zastrow M, Mucke L, Finkbeiner S, Gan L, Sestan N, Ward ME, Huttenhain R, Nowakowski TJ, Bellen HJ, Frank LM, Khokha MK, Lifton RP, Kampmann M, Ideker T, State MW, Krogan NJ. Willsey AJ, et al. Cell. 2018 Jul 26;174(3):505-520. doi: 10.1016/j.cell.2018.06.016. Cell. 2018. PMID: 30053424 Free PMC article. Review.
A single-cell atlas of the normal and malformed human brain vasculature.
Winkler EA, Kim CN, Ross JM, Garcia JH, Gil E, Oh I, Chen LQ, Wu D, Catapano JS, Raygor K, Narsinh K, Kim H, Weinsheimer S, Cooke DL, Walcott BP, Lawton MT, Gupta N, Zlokovic BV, Chang EF, Abla AA, Lim DA, Nowakowski TJ. Winkler EA, et al. Among authors: chang ef. Science. 2022 Mar 4;375(6584):eabi7377. doi: 10.1126/science.abi7377. Epub 2022 Mar 4. Science. 2022. PMID: 35084939 Free PMC article.
Glioblastoma remodelling of human neural circuits decreases survival.
Krishna S, Choudhury A, Keough MB, Seo K, Ni L, Kakaizada S, Lee A, Aabedi A, Popova G, Lipkin B, Cao C, Nava Gonzales C, Sudharshan R, Egladyous A, Almeida N, Zhang Y, Molinaro AM, Venkatesh HS, Daniel AGS, Shamardani K, Hyer J, Chang EF, Findlay A, Phillips JJ, Nagarajan S, Raleigh DR, Brang D, Monje M, Hervey-Jumper SL. Krishna S, et al. Among authors: chang ef. Nature. 2023 May;617(7961):599-607. doi: 10.1038/s41586-023-06036-1. Epub 2023 May 3. Nature. 2023. PMID: 37138086 Free PMC article.
An Amygdala-Hippocampus Subnetwork that Encodes Variation in Human Mood.
Kirkby LA, Luongo FJ, Lee MB, Nahum M, Van Vleet TM, Rao VR, Dawes HE, Chang EF, Sohal VS. Kirkby LA, et al. Among authors: chang ef. Cell. 2018 Nov 29;175(6):1688-1700.e14. doi: 10.1016/j.cell.2018.10.005. Epub 2018 Nov 8. Cell. 2018. PMID: 30415834 Free article. Clinical Trial.
Closed-loop neurostimulation for the treatment of psychiatric disorders.
Sellers KK, Cohen JL, Khambhati AN, Fan JM, Lee AM, Chang EF, Krystal AD. Sellers KK, et al. Among authors: chang ef. Neuropsychopharmacology. 2024 Jan;49(1):163-178. doi: 10.1038/s41386-023-01631-2. Epub 2023 Jun 27. Neuropsychopharmacology. 2024. PMID: 37369777 Review.
Encoding of melody in the human auditory cortex.
Sankaran N, Leonard MK, Theunissen F, Chang EF. Sankaran N, et al. Among authors: chang ef. Sci Adv. 2024 Feb 16;10(7):eadk0010. doi: 10.1126/sciadv.adk0010. Epub 2024 Feb 16. Sci Adv. 2024. PMID: 38363839 Free PMC article.
325 results