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47 results

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Page 1
Lipodystrophy in methylmalonic acidemia associated with elevated FGF21 and abnormal methylmalonylation.
Manoli I, Sysol JR, Head PE, Epping MW, Gavrilova O, Crocker MK, Sloan JL, Koutsoukos SA, Wang C, Ktena YP, Mendelson S, Pass AR, Zerfas PM, Hoffmann V, Vernon HJ, Fletcher LA, Reynolds JC, Tsokos MG, Stratakis CA, Voss SD, Chen KY, Brown RJ, Hamosh A, Berry GT, Chen XS, Yanovski JA, Venditti CP. Manoli I, et al. Among authors: fletcher la. JCI Insight. 2024 Feb 22;9(4):e174097. doi: 10.1172/jci.insight.174097. JCI Insight. 2024. PMID: 38271099 Free PMC article.
Associations of sleep patterns with metabolic syndrome indices, body composition, and energy intake in children and adolescents.
Mi SJ, Kelly NR, Brychta RJ, Grammer AC, Jaramillo M, Chen KY, Fletcher LA, Bernstein SB, Courville AB, Shank LM, Pomeroy JJ, Brady SM, Broadney MM, Tanofsky-Kraff M, Yanovski JA. Mi SJ, et al. Among authors: fletcher la. Pediatr Obes. 2019 Jun;14(6):e12507. doi: 10.1111/ijpo.12507. Epub 2019 Jan 31. Pediatr Obes. 2019. PMID: 30702801 Free PMC article.
Quantification of the Capacity for Cold-Induced Thermogenesis in Young Men With and Without Obesity.
Brychta RJ, Huang S, Wang J, Leitner BP, Hattenbach JD, Bell SL, Fletcher LA, Perron Wood R, Idelson CR, Duckworth CJ, McGehee S, Courville AB, Bernstein SB, Reitman ML, Cypess AM, Chen KY. Brychta RJ, et al. Among authors: fletcher la. J Clin Endocrinol Metab. 2019 Oct 1;104(10):4865-4878. doi: 10.1210/jc.2019-00728. J Clin Endocrinol Metab. 2019. PMID: 31150063 Free PMC article. Clinical Trial.
Sexual Dimorphisms in Adult Human Brown Adipose Tissue.
Fletcher LA, Kim K, Leitner BP, Cassimatis TM, O'Mara AE, Johnson JW, Halprin MS, McGehee SM, Brychta RJ, Cypess AM, Chen KY. Fletcher LA, et al. Obesity (Silver Spring). 2020 Feb;28(2):241-246. doi: 10.1002/oby.22698. Obesity (Silver Spring). 2020. PMID: 31970907 Free PMC article.
1-13C-propionate breath testing as a surrogate endpoint to assess efficacy of liver-directed therapies in methylmalonic acidemia (MMA).
Manoli I, Pass AR, Harrington EA, Sloan JL, Gagné J, McCoy S, Bell SL, Hattenbach JD, Leitner BP, Duckworth CJ, Fletcher LA, Cassimatis TM, Galarreta CI, Thurm A, Snow J, Van Ryzin C, Ferry S, Mew NA, Shchelochkov OA, Chen KY, Venditti CP. Manoli I, et al. Among authors: fletcher la. Genet Med. 2021 Aug;23(8):1522-1533. doi: 10.1038/s41436-021-01143-8. Epub 2021 Apr 5. Genet Med. 2021. PMID: 33820958 Free PMC article.
Correction to: 1-13C-propionate breath testing as a surrogate endpoint to assess efficacy of liver-directed therapies in methylmalonic acidemia (MMA).
Manoli I, Pass AR, Harrington EA, Sloan JL, Gagné J, McCoy S, Bell SL, Hattenbach JD, Leitner BP, Duckworth CJ, Fletcher LA, Cassimatis TM, Galarreta CI, Thurm A, Snow J, Van Ryzin C, Ferry S, Mew NA, Shchelochkov OA, Chen KY, Venditti CP. Manoli I, et al. Among authors: fletcher la. Genet Med. 2021 Nov;23(11):2233. doi: 10.1038/s41436-021-01188-9. Genet Med. 2021. PMID: 33972722 Free PMC article. No abstract available.
The thermoneutral zone in women takes an "arctic" shift compared to men.
Brychta RJ, McGehee S, Huang S, Leitner BP, Duckworth CJ, Fletcher LA, Kim K, Cassimatis TM, Israni NS, Lea HJ, Lentz TN, Pierce AE, Jiang A, LaMunion SR, Thomas RJ, Ishihara A, Courville AB, Yang SB, Reitman ML, Cypess AM, Chen KY. Brychta RJ, et al. Among authors: fletcher la. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2311116121. doi: 10.1073/pnas.2311116121. Epub 2024 Apr 29. Proc Natl Acad Sci U S A. 2024. PMID: 38683977
Regulation of Human Adipose Tissue Activation, Gallbladder Size, and Bile Acid Metabolism by a β3-Adrenergic Receptor Agonist.
Baskin AS, Linderman JD, Brychta RJ, McGehee S, Anflick-Chames E, Cero C, Johnson JW, O'Mara AE, Fletcher LA, Leitner BP, Duckworth CJ, Huang S, Cai H, Garraffo HM, Millo CM, Dieckmann W, Tolstikov V, Chen EY, Gao F, Narain NR, Kiebish MA, Walter PJ, Herscovitch P, Chen KY, Cypess AM. Baskin AS, et al. Among authors: fletcher la. Diabetes. 2018 Oct;67(10):2113-2125. doi: 10.2337/db18-0462. Epub 2018 Jul 6. Diabetes. 2018. PMID: 29980535 Free PMC article. Clinical Trial.
Opportunities and challenges in the therapeutic activation of human energy expenditure and thermogenesis to manage obesity.
Chen KY, Brychta RJ, Abdul Sater Z, Cassimatis TM, Cero C, Fletcher LA, Israni NS, Johnson JW, Lea HJ, Linderman JD, O'Mara AE, Zhu KY, Cypess AM. Chen KY, et al. Among authors: fletcher la. J Biol Chem. 2020 Feb 14;295(7):1926-1942. doi: 10.1074/jbc.REV119.007363. Epub 2019 Dec 30. J Biol Chem. 2020. PMID: 31914415 Free PMC article. Review.
47 results