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Myeloid cell expression of CD200R is modulated in active TB disease and regulates Mycobacterium tuberculosis infection in a biomimetic model.
Ahmed M, Tezera LB, Herbert N, Chambers M, Reichmann MT, Nargan K, Kloverpris H, Karim F, Hlatshwayo M, Madensein R, Habesh M, Hoque M, Steyn AJC, Elkington PT, Leslie AJ. Ahmed M, et al. Among authors: steyn ajc. Front Immunol. 2024 Apr 30;15:1360412. doi: 10.3389/fimmu.2024.1360412. eCollection 2024. Front Immunol. 2024. PMID: 38745652 Free PMC article.
Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise.
Coussens AK, Zaidi SMA, Allwood BW, Dewan PK, Gray G, Kohli M, Kredo T, Marais BJ, Marks GB, Martinez L, Ruhwald M, Scriba TJ, Seddon JA, Tisile P, Warner DF, Wilkinson RJ, Esmail H, Houben RMGJ; International Consensus for Early TB (ICE-TB) group. Coussens AK, et al. Lancet Respir Med. 2024 Jun;12(6):484-498. doi: 10.1016/S2213-2600(24)00028-6. Epub 2024 Mar 22. Lancet Respir Med. 2024. PMID: 38527485 Review.
Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells.
Olmo-Fontánez AM, Scordo JM, Schami A, Garcia-Vilanova A, Pino PA, Hicks A, Mishra R, Jose Maselli D, Peters JI, Restrepo BI, Nargan K, Naidoo T, Clemens DL, Steyn AJC, Thacker VV, Turner J, Schlesinger LS, Torrelles JB. Olmo-Fontánez AM, et al. Among authors: steyn ajc. Mucosal Immunol. 2024 Apr;17(2):155-168. doi: 10.1016/j.mucimm.2024.01.001. Epub 2024 Jan 6. Mucosal Immunol. 2024. PMID: 38185331 Free PMC article.
A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis.
Adolph C, Cheung CY, McNeil MB, Jowsey WJ, Williams ZC, Hards K, Harold LK, Aboelela A, Bujaroski RS, Buckley BJ, Tyndall JDA, Li Z, Langer JD, Preiss L, Meier T, Steyn AJC, Rhee KY, Berney M, Kelso MJ, Cook GM. Adolph C, et al. Among authors: steyn ajc. Cell Chem Biol. 2024 Apr 18;31(4):683-698.e7. doi: 10.1016/j.chembiol.2023.12.002. Epub 2023 Dec 26. Cell Chem Biol. 2024. PMID: 38151019
161 results