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Page 1
Chelation of Mitochondrial Iron as an Antiparasitic Strategy.
Arbon D, Mach J, Čadková A, Sipkova A, Stursa J, Klanicová K, Machado M, Ganter M, Levytska V, Sojka D, Truksa J, Werner L, Sutak R. Arbon D, et al. Among authors: stursa j. ACS Infect Dis. 2024 Feb 9;10(2):676-687. doi: 10.1021/acsinfecdis.3c00529. Epub 2024 Jan 30. ACS Infect Dis. 2024. PMID: 38287902 Free PMC article.
Mitochondrially targeted tamoxifen as anticancer therapy: case series of patients with renal cell carcinoma treated in a phase I/Ib clinical trial.
Bielcikova Z, Werner L, Stursa J, Cerny V, Krizova L, Spacek J, Hlousek S, Vocka M, Bartosova O, Pesta M, Kolostova K, Klezl P, Bobek V, Truksa J, Stemberkova-Hubackova S, Petruzelka L, Michalek P, Neuzil J. Bielcikova Z, et al. Among authors: stursa j. Ther Adv Med Oncol. 2023 Sep 30;15:17588359231197957. doi: 10.1177/17588359231197957. eCollection 2023. Ther Adv Med Oncol. 2023. PMID: 37786538 Free PMC article.
Mitochondrially targeted tamoxifen in patients with metastatic solid tumours: an open-label, phase I/Ib single-centre trial.
Bielcikova Z, Stursa J, Krizova L, Dong L, Spacek J, Hlousek S, Vocka M, Rohlenova K, Bartosova O, Cerny V, Padrta T, Pesta M, Michalek P, Hubackova SS, Kolostova K, Pospisilova E, Bobek V, Klezl P, Zobalova R, Endaya B, Rohlena J, Petruzelka L, Werner L, Neuzil J. Bielcikova Z, et al. Among authors: stursa j. EClinicalMedicine. 2023 Feb 23;57:101873. doi: 10.1016/j.eclinm.2023.101873. eCollection 2023 Mar. EClinicalMedicine. 2023. PMID: 37064512 Free PMC article.
Repurposing of MitoTam: Novel Anti-Cancer Drug Candidate Exhibits Potent Activity against Major Protozoan and Fungal Pathogens.
Arbon D, Ženíšková K, Šubrtová K, Mach J, Štursa J, Machado M, Zahedifard F, Leštinová T, Hierro-Yap C, Neuzil J, Volf P, Ganter M, Zoltner M, Zíková A, Werner L, Sutak R. Arbon D, et al. Among authors: stursa j. Antimicrob Agents Chemother. 2022 Aug 16;66(8):e0072722. doi: 10.1128/aac.00727-22. Epub 2022 Jul 20. Antimicrob Agents Chemother. 2022. PMID: 35856666 Free PMC article.
Mitochondrially targeted tamoxifen alleviates markers of obesity and type 2 diabetes mellitus in mice.
Vacurova E, Trnovska J, Svoboda P, Skop V, Novosadova V, Reguera DP, Petrezselyová S, Piavaux B, Endaya B, Spoutil F, Zudova D, Stursa J, Melcova M, Bielcikova Z, Werner L, Prochazka J, Sedlacek R, Huttl M, Hubackova SS, Haluzik M, Neuzil J. Vacurova E, et al. Among authors: stursa j. Nat Commun. 2022 Apr 6;13(1):1866. doi: 10.1038/s41467-022-29486-z. Nat Commun. 2022. PMID: 35387987 Free PMC article.
Simultaneous targeting of mitochondrial metabolism and immune checkpoints as a new strategy for renal cancer therapy.
Stemberkova-Hubackova S, Zobalova R, Dubisova M, Smigova J, Dvorakova S, Korinkova K, Ezrova Z, Endaya B, Blazkova K, Vlcak E, Brisudova P, Le DT, Juhas S, Rosel D, Daniela Kelemen C, Sovilj D, Vacurova E, Cajka T, Filimonenko V, Dong L, Andera L, Hozak P, Brabek J, Bielcikova Z, Stursa J, Werner L, Neuzil J. Stemberkova-Hubackova S, et al. Among authors: stursa j. Clin Transl Med. 2022 Mar;12(3):e645. doi: 10.1002/ctm2.645. Clin Transl Med. 2022. PMID: 35352502 Free PMC article. No abstract available.
Targeting Mitochondrial Iron Metabolism Suppresses Tumor Growth and Metastasis by Inducing Mitochondrial Dysfunction and Mitophagy.
Sandoval-Acuña C, Torrealba N, Tomkova V, Jadhav SB, Blazkova K, Merta L, Lettlova S, Adamcová MK, Rosel D, Brábek J, Neuzil J, Stursa J, Werner L, Truksa J. Sandoval-Acuña C, et al. Among authors: stursa j. Cancer Res. 2021 May 1;81(9):2289-2303. doi: 10.1158/0008-5472.CAN-20-1628. Epub 2021 Mar 8. Cancer Res. 2021. PMID: 33685989
45 results