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Page 1
Chelation of Mitochondrial Iron as an Antiparasitic Strategy.
Arbon D, Mach J, Čadková A, Sipkova A, Stursa J, Klanicová K, Machado M, Ganter M, Levytska V, Sojka D, Truksa J, Werner L, Sutak R. Arbon D, et al. Among authors: werner l. ACS Infect Dis. 2024 Feb 9;10(2):676-687. doi: 10.1021/acsinfecdis.3c00529. Epub 2024 Jan 30. ACS Infect Dis. 2024. PMID: 38287902 Free PMC article.
Repurposing of MitoTam: Novel Anti-Cancer Drug Candidate Exhibits Potent Activity against Major Protozoan and Fungal Pathogens.
Arbon D, Ženíšková K, Šubrtová K, Mach J, Štursa J, Machado M, Zahedifard F, Leštinová T, Hierro-Yap C, Neuzil J, Volf P, Ganter M, Zoltner M, Zíková A, Werner L, Sutak R. Arbon D, et al. Among authors: werner l. Antimicrob Agents Chemother. 2022 Aug 16;66(8):e0072722. doi: 10.1128/aac.00727-22. Epub 2022 Jul 20. Antimicrob Agents Chemother. 2022. PMID: 35856666 Free PMC article.
Targeting Mitochondrial Iron Metabolism Suppresses Tumor Growth and Metastasis by Inducing Mitochondrial Dysfunction and Mitophagy.
Sandoval-Acuña C, Torrealba N, Tomkova V, Jadhav SB, Blazkova K, Merta L, Lettlova S, Adamcová MK, Rosel D, Brábek J, Neuzil J, Stursa J, Werner L, Truksa J. Sandoval-Acuña C, et al. Among authors: werner l. Cancer Res. 2021 May 1;81(9):2289-2303. doi: 10.1158/0008-5472.CAN-20-1628. Epub 2021 Mar 8. Cancer Res. 2021. PMID: 33685989
Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer.
Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork-Geleta A, Blecha J, Endaya B, Werner L, Cerny J, Zobalova R, Goodwin J, Spacek T, Alizadeh Pesdar E, Yan B, Nguyen MN, Vondrusova M, Sobol M, Jezek P, Hozak P, Truksa J, Rohlena J, Dong LF, Neuzil J. Rohlenova K, et al. Among authors: werner l. Antioxid Redox Signal. 2017 Jan 10;26(2):84-103. doi: 10.1089/ars.2016.6677. Epub 2016 Aug 22. Antioxid Redox Signal. 2017. PMID: 27392540 Free PMC article.
Mitochondrially targeted tamoxifen as anticancer therapy: case series of patients with renal cell carcinoma treated in a phase I/Ib clinical trial.
Bielcikova Z, Werner L, Stursa J, Cerny V, Krizova L, Spacek J, Hlousek S, Vocka M, Bartosova O, Pesta M, Kolostova K, Klezl P, Bobek V, Truksa J, Stemberkova-Hubackova S, Petruzelka L, Michalek P, Neuzil J. Bielcikova Z, et al. Among authors: werner l. Ther Adv Med Oncol. 2023 Sep 30;15:17588359231197957. doi: 10.1177/17588359231197957. eCollection 2023. Ther Adv Med Oncol. 2023. PMID: 37786538 Free PMC article.
Simultaneous targeting of mitochondrial metabolism and immune checkpoints as a new strategy for renal cancer therapy.
Stemberkova-Hubackova S, Zobalova R, Dubisova M, Smigova J, Dvorakova S, Korinkova K, Ezrova Z, Endaya B, Blazkova K, Vlcak E, Brisudova P, Le DT, Juhas S, Rosel D, Daniela Kelemen C, Sovilj D, Vacurova E, Cajka T, Filimonenko V, Dong L, Andera L, Hozak P, Brabek J, Bielcikova Z, Stursa J, Werner L, Neuzil J. Stemberkova-Hubackova S, et al. Among authors: werner l. Clin Transl Med. 2022 Mar;12(3):e645. doi: 10.1002/ctm2.645. Clin Transl Med. 2022. PMID: 35352502 Free PMC article. No abstract available.
Selective elimination of senescent cells by mitochondrial targeting is regulated by ANT2.
Hubackova S, Davidova E, Rohlenova K, Stursa J, Werner L, Andera L, Dong L, Terp MG, Hodny Z, Ditzel HJ, Rohlena J, Neuzil J. Hubackova S, et al. Among authors: werner l. Cell Death Differ. 2019 Jan;26(2):276-290. doi: 10.1038/s41418-018-0118-3. Epub 2018 May 21. Cell Death Differ. 2019. PMID: 29786070 Free PMC article.
830 results