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7-Dehydrocholesterol is an endogenous suppressor of ferroptosis.
Freitas FP, Alborzinia H, Dos Santos AF, Nepachalovich P, Pedrera L, Zilka O, Inague A, Klein C, Aroua N, Kaushal K, Kast B, Lorenz SM, Kunz V, Nehring H, Xavier da Silva TN, Chen Z, Atici S, Doll SG, Schaefer EL, Ekpo I, Schmitz W, Horling A, Imming P, Miyamoto S, Wehman AM, Genaro-Mattos TC, Mirnics K, Kumar L, Klein-Seetharaman J, Meierjohann S, Weigand I, Kroiss M, Bornkamm GW, Gomes F, Netto LES, Sathian MB, Konrad DB, Covey DF, Michalke B, Bommert K, Bargou RC, Garcia-Saez A, Pratt DA, Fedorova M, Trumpp A, Conrad M, Friedmann Angeli JP. Freitas FP, et al. Among authors: pedrera l. Nature. 2024 Feb;626(7998):401-410. doi: 10.1038/s41586-023-06878-9. Epub 2024 Jan 31. Nature. 2024. PMID: 38297129
Techniques for studying membrane pores.
Ros U, Pedrera L, Garcia-Saez AJ. Ros U, et al. Among authors: pedrera l. Curr Opin Struct Biol. 2021 Aug;69:108-116. doi: 10.1016/j.sbi.2021.03.012. Epub 2021 May 1. Curr Opin Struct Biol. 2021. PMID: 33945958 Review.
Disrupting a key hydrophobic pair in the oligomerization interface of the actinoporins impairs their pore-forming activity.
Mesa-Galloso H, Delgado-Magnero KH, Cabezas S, López-Castilla A, Hernández-González JE, Pedrera L, Alvarez C, Peter Tieleman D, García-Sáez AJ, Lanio ME, Ros U, Valiente PA. Mesa-Galloso H, et al. Among authors: pedrera l. Protein Sci. 2017 Mar;26(3):550-565. doi: 10.1002/pro.3104. Epub 2017 Feb 23. Protein Sci. 2017. PMID: 28000294 Free PMC article.
15 results