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Page 1
Manufacture of CD22 CAR T cells following positive versus negative selection results in distinct cytokine secretion profiles and γδ T cell output.
Song HW, Benzaoui M, Dwivedi A, Underwood S, Shao L, Achar S, Posarac V, Remley VA, Prochazkova M, Cai Y, Jin P, Somerville RP, Stroncek DF, Altan-Bonnet G, Shah NN, Chien CD, Taylor N, Highfill SL. Song HW, et al. Among authors: altan bonnet g. Mol Ther Methods Clin Dev. 2023 Dec 11;32(1):101171. doi: 10.1016/j.omtm.2023.101171. eCollection 2024 Mar 14. Mol Ther Methods Clin Dev. 2023. PMID: 38298420 Free PMC article.
Publisher Correction: CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides.
Gaud G, Achar S, Bourassa FXP, Davies J, Hatzihristidis T, Choi S, Kondo T, Gossa S, Lee J, Juneau P, Taylor N, Hinrichs CS, McGavern DB, François P, Altan-Bonnet G, Love PE. Gaud G, et al. Among authors: altan bonnet g. Nat Immunol. 2024 Mar;25(3):579. doi: 10.1038/s41590-023-01725-5. Nat Immunol. 2024. PMID: 38057618 No abstract available.
CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides.
Gaud G, Achar S, Bourassa FXP, Davies J, Hatzihristidis T, Choi S, Kondo T, Gossa S, Lee J, Juneau P, Taylor N, Hinrichs CS, McGavern DB, François P, Altan-Bonnet G, Love PE. Gaud G, et al. Among authors: altan bonnet g. Nat Immunol. 2023 Dec;24(12):2121-2134. doi: 10.1038/s41590-023-01663-2. Epub 2023 Nov 9. Nat Immunol. 2023. PMID: 37945821
Apoptotic contraction drives target cell release by cytotoxic T cells.
Sanchez EE, Tello-Lafoz M, Guo AJ, de Jesus M, Elbanna YA, Winer BY, Budhu S, Chan E, Rosiek E, Kondo T, DuSold J, Taylor N, Altan-Bonnet G, Olson MF, Huse M. Sanchez EE, et al. Among authors: altan bonnet g. Nat Immunol. 2023 Sep;24(9):1434-1442. doi: 10.1038/s41590-023-01572-4. Epub 2023 Jul 27. Nat Immunol. 2023. PMID: 37500886
A stem cell epigenome is associated with primary nonresponse to CD19 CAR T cells in pediatric acute lymphoblastic leukemia.
Masih KE, Gardner RA, Chou HC, Abdelmaksoud A, Song YK, Mariani L, Gangalapudi V, Gryder BE, Wilson AL, Adebola SO, Stanton BZ, Wang C, Milewski D, Kim YY, Tian M, Cheuk AT, Wen X, Zhang Y, Altan-Bonnet G, Kelly MC, Wei JS, Bulyk ML, Jensen MC, Orentas RJ, Khan J. Masih KE, et al. Among authors: altan bonnet g. Blood Adv. 2023 Aug 8;7(15):4218-4232. doi: 10.1182/bloodadvances.2022008977. Blood Adv. 2023. PMID: 36607839 Free PMC article.
Engineering time-controlled immunotherapy.
Salazar-Cavazos E, Altan-Bonnet G. Salazar-Cavazos E, et al. Among authors: altan bonnet g. Science. 2022 Dec 16;378(6625):1175-1176. doi: 10.1126/science.adf5318. Epub 2022 Dec 15. Science. 2022. PMID: 36520890
HAL-X: Scalable hierarchical clustering for rapid and tunable single-cell analysis.
Anibal J, Day AG, Bahadiroglu E, O'Neil L, Phan L, Peltekian A, Erez A, Kaplan M, Altan-Bonnet G, Mehta P. Anibal J, et al. Among authors: altan bonnet g. PLoS Comput Biol. 2022 Oct 3;18(10):e1010349. doi: 10.1371/journal.pcbi.1010349. eCollection 2022 Oct. PLoS Comput Biol. 2022. PMID: 36191000 Free PMC article.
CD19/22 CAR T cells in children and young adults with B-ALL: phase 1 results and development of a novel bicistronic CAR.
Shalabi H, Qin H, Su A, Yates B, Wolters PL, Steinberg SM, Ligon JA, Silbert S, DéDé K, Benzaoui M, Goldberg S, Achar S, Schneider D, Shahani SA, Little L, Foley T, Molina JC, Panch S, Mackall CL, Lee DW, Chien CD, Pouzolles M, Ahlman M, Yuan CM, Wang HW, Wang Y, Inglefield J, Toledo-Tamula MA, Martin S, Highfill SL, Altan-Bonnet G, Stroncek D, Fry TJ, Taylor N, Shah NN. Shalabi H, et al. Among authors: altan bonnet g. Blood. 2022 Aug 4;140(5):451-463. doi: 10.1182/blood.2022015795. Blood. 2022. PMID: 35605184 Free PMC article. Clinical Trial.
69 results