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Manufacture of CD22 CAR T cells following positive versus negative selection results in distinct cytokine secretion profiles and γδ T cell output.
Song HW, Benzaoui M, Dwivedi A, Underwood S, Shao L, Achar S, Posarac V, Remley VA, Prochazkova M, Cai Y, Jin P, Somerville RP, Stroncek DF, Altan-Bonnet G, Shah NN, Chien CD, Taylor N, Highfill SL. Song HW, et al. Among authors: benzaoui m. Mol Ther Methods Clin Dev. 2023 Dec 11;32(1):101171. doi: 10.1016/j.omtm.2023.101171. eCollection 2024 Mar 14. Mol Ther Methods Clin Dev. 2023. PMID: 38298420 Free PMC article.
An optimized bicistronic chimeric antigen receptor against GPC2 or CD276 overcomes heterogeneous expression in neuroblastoma.
Tian M, Cheuk AT, Wei JS, Abdelmaksoud A, Chou HC, Milewski D, Kelly MC, Song YK, Dower CM, Li N, Qin H, Kim YY, Wu JT, Wen X, Benzaoui M, Masih KE, Wu X, Zhang Z, Badr S, Taylor N, Croix BS, Ho M, Khan J. Tian M, et al. Among authors: benzaoui m. J Clin Invest. 2022 Aug 15;132(16):e155621. doi: 10.1172/JCI155621. J Clin Invest. 2022. PMID: 35852863 Free PMC article.
CD19/22 CAR T cells in children and young adults with B-ALL: phase 1 results and development of a novel bicistronic CAR.
Shalabi H, Qin H, Su A, Yates B, Wolters PL, Steinberg SM, Ligon JA, Silbert S, DéDé K, Benzaoui M, Goldberg S, Achar S, Schneider D, Shahani SA, Little L, Foley T, Molina JC, Panch S, Mackall CL, Lee DW, Chien CD, Pouzolles M, Ahlman M, Yuan CM, Wang HW, Wang Y, Inglefield J, Toledo-Tamula MA, Martin S, Highfill SL, Altan-Bonnet G, Stroncek D, Fry TJ, Taylor N, Shah NN. Shalabi H, et al. Among authors: benzaoui m. Blood. 2022 Aug 4;140(5):451-463. doi: 10.1182/blood.2022015795. Blood. 2022. PMID: 35605184 Free PMC article. Clinical Trial.
Clinical and Product Features Associated with Outcome of DLBCL Patients to CD19-Targeted CAR T-Cell Therapy.
Lamure S, Van Laethem F, De Verbizier D, Lozano C, Gehlkopf E, Tudesq JJ, Serrand C, Benzaoui M, Kanouni T, Quintard A, De Vos J, Tchernonog E, Platon L, Ayrignac X, Ceballos P, Sirvent A, François M, Guedon H, Quittet P, Mongellaz C, Conte A, Herbaux C, Bret C, Taylor N, Dardalhon V, Cartron G. Lamure S, et al. Among authors: benzaoui m. Cancers (Basel). 2021 Aug 25;13(17):4279. doi: 10.3390/cancers13174279. Cancers (Basel). 2021. PMID: 34503088 Free PMC article.