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Page 1
Intratumoral antigen signaling traps CD8+ T cells to confine exhaustion to the tumor site.
Takahashi M, So TY, Chamberlain-Evans V, Hughes R, Yam-Puc JC, Kania K, Ruhle M, Mann T, Schuijs MJ, Coupland P, Naisbitt D, Halim TYF, Lyons PA, Lio P, Roychoudhuri R, Okkenhaug K, Adams DJ, Smith KGC, Jodrell DI, Chapman MA, Thaventhiran JED. Takahashi M, et al. Among authors: yam puc jc. Sci Immunol. 2024 May 24;9(95):eade2094. doi: 10.1126/sciimmunol.ade2094. Epub 2024 May 24. Sci Immunol. 2024. PMID: 38787961
Bioengineered small extracellular vesicles deliver multiple SARS-CoV-2 antigenic fragments and drive a broad immunological response.
Jackson HK, Long HM, Yam-Puc JC, Palmulli R, Haigh TA, Gerber PP, Lee JS, Matheson NJ, Young L, Trowsdale J, Lo M, Taylor GS, Thaventhiran JE, Edgar JR. Jackson HK, et al. Among authors: yam puc jc. J Extracell Vesicles. 2024 Feb;13(2):e12412. doi: 10.1002/jev2.12412. J Extracell Vesicles. 2024. PMID: 38339765 Free PMC article.
Stability of gut microbiome after COVID-19 vaccination in healthy and immuno-compromised individuals.
Boston RH, Guan R, Kalmar L, Beier S, Horner EC, Beristain-Covarrubias N, Yam-Puc JC, Pereyra Gerber P, Faria L, Kuroshchenkova A, Lindell AE, Blasche S, Correa-Noguera A, Elmer A, Saunders C, Bermperi A, Jose S, Kingston N; CITIID-NIHR COVID-19 BioResource Collaboration; Grigoriadou S, Staples E, Buckland MS, Lear S, Matheson NJ, Benes V, Parkinson C, Thaventhiran JE, Patil KR. Boston RH, et al. Among authors: yam puc jc. Life Sci Alliance. 2024 Feb 5;7(4):e202302529. doi: 10.26508/lsa.202302529. Print 2024 Apr. Life Sci Alliance. 2024. PMID: 38316462 Free PMC article.
N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting.
Mulroney TE, Pöyry T, Yam-Puc JC, Rust M, Harvey RF, Kalmar L, Horner E, Booth L, Ferreira AP, Stoneley M, Sawarkar R, Mentzer AJ, Lilley KS, Smales CM, von der Haar T, Turtle L, Dunachie S, Klenerman P, Thaventhiran JED, Willis AE. Mulroney TE, et al. Among authors: yam puc jc. Nature. 2024 Jan;625(7993):189-194. doi: 10.1038/s41586-023-06800-3. Epub 2023 Dec 6. Nature. 2024. PMID: 38057663 Free PMC article.
Elevated levels of enteric IgA in an unimmunised mouse model of Hyper IgM syndrome derived from gut-associated secondary lymph organs even in the absence of germinal centres.
Hernandez-Cazares F, Maqueda-Alfaro RA, Lopez-Saucedo C, Martinez-Barnetche J, Yam-Puc JC, Estrada-Parra S, Flores-Romo L, Estrada-Garcia T. Hernandez-Cazares F, et al. Among authors: yam puc jc. Front Cell Infect Microbiol. 2023 Jun 29;13:1172021. doi: 10.3389/fcimb.2023.1172021. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37457961 Free PMC article.
Age-associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade.
Yam-Puc JC, Hosseini Z, Horner EC, Gerber PP, Beristain-Covarrubias N, Hughes R, Lulla A, Rust M, Boston R, Ali M, Fischer K, Simmons-Rosello E, O'Reilly M, Robson H, Booth LH, Kahanawita L, Correa-Noguera A, Favara D, Ceron-Gutierrez L, Keller B, Craxton A, Anderson GSF, Sun XM, Elmer A, Saunders C, Bermperi A, Jose S, Kingston N, Mulroney TE, Piñon LPG; CITIID-NIHR COVID−19 BioResource Collaboration; Chapman MA, Grigoriadou S, MacFarlane M, Willis AE, Patil KR, Spencer S, Staples E, Warnatz K, Buckland MS, Hollfelder F, Hyvönen M, Döffinger R, Parkinson C, Lear S, Matheson NJ, Thaventhiran JED. Yam-Puc JC, et al. Nat Commun. 2023 Jun 27;14(1):3292. doi: 10.1038/s41467-023-38810-0. Nat Commun. 2023. PMID: 37369658 Free PMC article.
Tfh cells and the germinal center are required for memory B cell formation & humoral immunity after ChAdOx1 nCoV-19 vaccination.
Foster WS, Lee JL, Thakur N, Newman J, Spencer AJ, Davies S, Woods D, Godfrey L, Hay IM, Innocentin S, Yam-Puc JC, Horner EC, Sharpe HJ, Thaventhiran JE, Bailey D, Lambe T, Linterman MA. Foster WS, et al. Among authors: yam puc jc. Cell Rep Med. 2022 Dec 20;3(12):100845. doi: 10.1016/j.xcrm.2022.100845. Epub 2022 Nov 15. Cell Rep Med. 2022. PMID: 36455555 Free PMC article.
Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift.
Zhang Y, Garcia-Ibanez L, Ulbricht C, Lok LSC, Pike JA, Mueller-Winkler J, Dennison TW, Ferdinand JR, Burnett CJM, Yam-Puc JC, Zhang L, Alfaro RM, Takahama Y, Ohigashi I, Brown G, Kurosaki T, Tybulewicz VLJ, Rot A, Hauser AE, Clatworthy MR, Toellner KM. Zhang Y, et al. Among authors: yam puc jc. Nat Commun. 2022 May 5;13(1):2460. doi: 10.1038/s41467-022-29978-y. Nat Commun. 2022. PMID: 35513371 Free PMC article.
TLR2 Regulates Mast Cell IL-6 and IL-13 Production During Listeria monocytogenes Infection.
Soria-Castro R, Alfaro-Doblado ÁR, Rodríguez-López G, Campillo-Navarro M, Meneses-Preza YG, Galán-Salinas A, Alvarez-Jimenez V, Yam-Puc JC, Munguía-Fuentes R, Domínguez-Flores A, Estrada-Parra S, Pérez-Tapia SM, Chávez-Blanco AD, Chacón-Salinas R. Soria-Castro R, et al. Among authors: yam puc jc. Front Immunol. 2021 Jun 14;12:650779. doi: 10.3389/fimmu.2021.650779. eCollection 2021. Front Immunol. 2021. PMID: 34194428 Free PMC article.
Robust Plasma Cell Response to Skin-Inoculated Dengue Virus in Mice.
Maqueda-Alfaro RA, Marcial-Juárez E, Calderón-Amador J, García-Cordero J, Orozco-Uribe M, Hernández-Cázares F, Medina-Pérez U, Sánchez-Torres LE, Flores-Langarica A, Cedillo-Barrón L, Yam-Puc JC, Flores-Romo L. Maqueda-Alfaro RA, et al. Among authors: yam puc jc. J Immunol Res. 2021 Apr 26;2021:5511841. doi: 10.1155/2021/5511841. eCollection 2021. J Immunol Res. 2021. PMID: 33997054 Free PMC article.
25 results