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Mitochondrial DNA replication stress triggers a pro-inflammatory endosomal pathway of nucleoid disposal.
Newman LE, Weiser Novak S, Rojas GR, Tadepalle N, Schiavon CR, Grotjahn DA, Towers CG, Tremblay MÈ, Donnelly MP, Ghosh S, Medina M, Rocha S, Rodriguez-Enriquez R, Chevez JA, Lemersal I, Manor U, Shadel GS. Newman LE, et al. Among authors: manor u. Nat Cell Biol. 2024 Feb;26(2):194-206. doi: 10.1038/s41556-023-01343-1. Epub 2024 Feb 8. Nat Cell Biol. 2024. PMID: 38332353
Impaired Mitochondrial Mobility in Charcot-Marie-Tooth Disease.
Schiavon CR, Shadel GS, Manor U. Schiavon CR, et al. Among authors: manor u. Front Cell Dev Biol. 2021 Feb 1;9:624823. doi: 10.3389/fcell.2021.624823. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33598463 Free PMC article.
Actin chromobody imaging reveals sub-organellar actin dynamics.
Schiavon CR, Zhang T, Zhao B, Moore AS, Wales P, Andrade LR, Wu M, Sung TC, Dayn Y, Feng JW, Quintero OA, Shadel GS, Grosse R, Manor U. Schiavon CR, et al. Among authors: manor u. Nat Methods. 2020 Sep;17(9):917-921. doi: 10.1038/s41592-020-0926-5. Epub 2020 Aug 10. Nat Methods. 2020. PMID: 32778832 Free PMC article.
Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1.
Malik N, Ferreira BI, Hollstein PE, Curtis SD, Trefts E, Weiser Novak S, Yu J, Gilson R, Hellberg K, Fang L, Sheridan A, Hah N, Shadel GS, Manor U, Shaw RJ. Malik N, et al. Among authors: manor u. Science. 2023 Apr 21;380(6642):eabj5559. doi: 10.1126/science.abj5559. Epub 2023 Apr 21. Science. 2023. PMID: 37079666 Free PMC article.
Deep learning-based point-scanning super-resolution imaging.
Fang L, Monroe F, Novak SW, Kirk L, Schiavon CR, Yu SB, Zhang T, Wu M, Kastner K, Latif AA, Lin Z, Shaw A, Kubota Y, Mendenhall J, Zhang Z, Pekkurnaz G, Harris K, Howard J, Manor U. Fang L, et al. Among authors: manor u. Nat Methods. 2021 Apr;18(4):406-416. doi: 10.1038/s41592-021-01080-z. Epub 2021 Mar 8. Nat Methods. 2021. PMID: 33686300 Free PMC article.
SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2.
Lei Y, Zhang J, Schiavon CR, He M, Chen L, Shen H, Zhang Y, Yin Q, Cho Y, Andrade L, Shadel GS, Hepokoski M, Lei T, Wang H, Zhang J, Yuan JX, Malhotra A, Manor U, Wang S, Yuan ZY, Shyy JY. Lei Y, et al. Among authors: manor u. Circ Res. 2021 Apr 30;128(9):1323-1326. doi: 10.1161/CIRCRESAHA.121.318902. Epub 2021 Mar 31. Circ Res. 2021. PMID: 33784827 Free PMC article. No abstract available.
The San Diego Nathan Shock Center: tackling the heterogeneity of aging.
Shadel GS, Adams PD, Berggren WT, Diedrich JK, Diffenderfer KE, Gage FH, Hah N, Hansen M, Hetzer MW, Molina AJA, Manor U, Marek K, O'Keefe DD, Pinto AFM, Sacco A, Sharpee TO, Shokriev MN, Zambetti S. Shadel GS, et al. Among authors: manor u. Geroscience. 2021 Oct;43(5):2139-2148. doi: 10.1007/s11357-021-00426-x. Epub 2021 Aug 9. Geroscience. 2021. PMID: 34370163 Free PMC article.
Obstructive Sleep Apnea-induced Endothelial Dysfunction Is Mediated by miR-210.
Shang F, Wang SC, Gongol B, Han SY, Cho Y, Schiavon CR, Chen L, Xing Y, Zhao Y, Ning M, Guo X, He F, Lei Y, Wang L, Manor U, Marin T, Chou KT, He M, Huang PH, Shyy JY, Malhotra A. Shang F, et al. Among authors: manor u. Am J Respir Crit Care Med. 2023 Feb 1;207(3):323-335. doi: 10.1164/rccm.202202-0394OC. Am J Respir Crit Care Med. 2023. PMID: 36191258 Free PMC article.
Regulation of the ER stress response by a mitochondrial microprotein.
Chu Q, Martinez TF, Novak SW, Donaldson CJ, Tan D, Vaughan JM, Chang T, Diedrich JK, Andrade L, Kim A, Zhang T, Manor U, Saghatelian A. Chu Q, et al. Among authors: manor u. Nat Commun. 2019 Oct 25;10(1):4883. doi: 10.1038/s41467-019-12816-z. Nat Commun. 2019. PMID: 31653868 Free PMC article.
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.
Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, Woo G, Fang L, Santisakultarm TP, Manor U, Xu R, Becerra CR, Borazanci E, Von Hoff DD, Grandgenett PM, Hollingsworth MA, Leblanc M, Umetsu SE, Collisson EA, Scadeng M, Lowy AM, Donahue TR, Reya T, Downes M, Evans RM, Wahl GM, Pawson T, Tian R, Hunter T. Shi Y, et al. Among authors: manor u. Nature. 2019 May;569(7754):131-135. doi: 10.1038/s41586-019-1130-6. Epub 2019 Apr 17. Nature. 2019. PMID: 30996350 Free PMC article.
77 results