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Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse.
Sommerfeld LC, Holmes AP, Yu TY, O'Shea C, Kavanagh DM, Pike JM, Wright T, Syeda F, Aljehani A, Kew T, Cardoso VR, Kabir SN, Hepburn C, Menon PR, Broadway-Stringer S, O'Reilly M, Witten A, Fortmueller L, Lutz S, Kulle A, Gkoutos GV, Pavlovic D, Arlt W, Lavery GG, Steeds R, Gehmlich K, Stoll M, Kirchhof P, Fabritz L. Sommerfeld LC, et al. Among authors: lavery gg. J Physiol. 2024 Feb 12. doi: 10.1113/JP284597. Online ahead of print. J Physiol. 2024. PMID: 38345865
Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass spectrometry (LC/MS/MS).
Krone N, Hughes BA, Lavery GG, Stewart PM, Arlt W, Shackleton CH. Krone N, et al. Among authors: lavery gg. J Steroid Biochem Mol Biol. 2010 Aug;121(3-5):496-504. doi: 10.1016/j.jsbmb.2010.04.010. Epub 2010 Apr 22. J Steroid Biochem Mol Biol. 2010. PMID: 20417277 Free PMC article. Review.
Premature adrenarche: novel lessons from early onset androgen excess.
Idkowiak J, Lavery GG, Dhir V, Barrett TG, Stewart PM, Krone N, Arlt W. Idkowiak J, et al. Among authors: lavery gg. Eur J Endocrinol. 2011 Aug;165(2):189-207. doi: 10.1530/EJE-11-0223. Epub 2011 May 26. Eur J Endocrinol. 2011. PMID: 21622478 Review.
Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency.
Lavery GG, Walker EA, Tiganescu A, Ride JP, Shackleton CH, Tomlinson JW, Connell JM, Ray DW, Biason-Lauber A, Malunowicz EM, Arlt W, Stewart PM. Lavery GG, et al. J Clin Endocrinol Metab. 2008 Oct;93(10):3827-32. doi: 10.1210/jc.2008-0743. Epub 2008 Jul 15. J Clin Endocrinol Metab. 2008. PMID: 18628520 Free PMC article.
Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin-resistant men.
Dollerup OL, Chubanava S, Agerholm M, Søndergård SD, Altıntaş A, Møller AB, Høyer KF, Ringgaard S, Stødkilde-Jørgensen H, Lavery GG, Barrès R, Larsen S, Prats C, Jessen N, Treebak JT. Dollerup OL, et al. Among authors: lavery gg. J Physiol. 2020 Feb;598(4):731-754. doi: 10.1113/JP278752. Epub 2019 Dec 26. J Physiol. 2020. PMID: 31710095 Free article. Clinical Trial.
A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics.
O'Reilly MW, Westgate CS, Hornby C, Botfield H, Taylor AE, Markey K, Mitchell JL, Scotton WJ, Mollan SP, Yiangou A, Jenkinson C, Gilligan LC, Sherlock M, Gibney J, Tomlinson JW, Lavery GG, Hodson DJ, Arlt W, Sinclair AJ. O'Reilly MW, et al. Among authors: lavery gg. JCI Insight. 2019 Mar 21;4(6):e125348. doi: 10.1172/jci.insight.125348. eCollection 2019 Mar 21. JCI Insight. 2019. PMID: 30753168 Free PMC article.
11βHSD1 Inhibition with AZD4017 Improves Lipid Profiles and Lean Muscle Mass in Idiopathic Intracranial Hypertension.
Hardy RS, Botfield H, Markey K, Mitchell JL, Alimajstorovic Z, Westgate CSJ, Sagmeister M, Fairclough RJ, Ottridge RS, Yiangou A, Storbeck KH, Taylor AE, Gilligan LC, Arlt W, Stewart PM, Tomlinson JW, Mollan SP, Lavery GG, Sinclair AJ. Hardy RS, et al. Among authors: lavery gg. J Clin Endocrinol Metab. 2021 Jan 1;106(1):174-187. doi: 10.1210/clinem/dgaa766. J Clin Endocrinol Metab. 2021. PMID: 33098644 Free PMC article. Clinical Trial.
Cognitive performance in idiopathic intracranial hypertension and relevance of intracranial pressure.
Grech O, Clouter A, Mitchell JL, Alimajstorovic Z, Ottridge RS, Yiangou A, Roque M, Tahrani AA, Nicholls M, Taylor AE, Shaheen F, Arlt W, Lavery GG, Shapiro K, Mollan SP, Sinclair AJ. Grech O, et al. Among authors: lavery gg. Brain Commun. 2021 Sep 2;3(3):fcab202. doi: 10.1093/braincomms/fcab202. eCollection 2021. Brain Commun. 2021. PMID: 34704028 Free PMC article.
161 results