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Case report: Refractory Evans syndrome in two patients with spondyloenchondrodysplasia with immune dysregulation treated successfully with JAK1/JAK2 inhibition.
Gernez Y, Narula M, Cepika AM, Valdes Camacho J, Hoyte EG, Mouradian K, Glader B, Singh D, Sathi B, Rao L, Tolin AL, Weinberg KI, Lewis DB, Bacchetta R, Weinacht KG. Gernez Y, et al. Among authors: narula m. Front Immunol. 2024 Jan 29;14:1328005. doi: 10.3389/fimmu.2023.1328005. eCollection 2023. Front Immunol. 2024. PMID: 38347954 Free PMC article. Review.
Alloantigen-specific type 1 regulatory T cells suppress through CTLA-4 and PD-1 pathways and persist long-term in patients.
Chen PP, Cepika AM, Agarwal-Hashmi R, Saini G, Uyeda MJ, Louis DM, Cieniewicz B, Narula M, Amaya Hernandez LC, Harre N, Xu L, Thomas BC, Ji X, Shiraz P, Tate KM, Margittai D, Bhatia N, Meyer E, Bertaina A, Davis MM, Bacchetta R, Roncarolo MG. Chen PP, et al. Among authors: narula m. Sci Transl Med. 2021 Oct 27;13(617):eabf5264. doi: 10.1126/scitranslmed.abf5264. Epub 2021 Oct 27. Sci Transl Med. 2021. PMID: 34705520 Free PMC article.
Epigenetic and immunological indicators of IPEX disease in subjects with FOXP3 gene mutation.
Narula M, Lakshmanan U, Borna S, Schulze JJ, Holmes TH, Harre N, Kirkey M, Ramachandran A, Tagi VM, Barzaghi F, Grunebaum E, Upton JEM, Hong-Diep Kim V, Wysocki C, Dimitriades VR, Weinberg K, Weinacht KG, Gernez Y, Sathi BK, Schelotto M, Johnson M, Olek S, Sachsenmaier C, Roncarolo MG, Bacchetta R. Narula M, et al. J Allergy Clin Immunol. 2023 Jan;151(1):233-246.e10. doi: 10.1016/j.jaci.2022.09.013. Epub 2022 Sep 21. J Allergy Clin Immunol. 2023. PMID: 36152823 Free article.
Identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with FOXP3 mutations.
Borna Š, Lee E, Nideffer J, Ramachandran A, Wang B, Baker J, Mavers M, Lakshmanan U, Narula M, Garrett AK, Schulze J, Olek S, Marois L, Gernez Y, Bhatia M, Chong HJ, Walter J, Kitcharoensakkul M, Lang A, Cooper MA, Bertaina A, Roncarolo MG, Meffre E, Bacchetta R. Borna Š, et al. Among authors: narula m. Sci Transl Med. 2023 Dec 20;15(727):eadg6822. doi: 10.1126/scitranslmed.adg6822. Epub 2023 Dec 20. Sci Transl Med. 2023. PMID: 38117899 Free PMC article.
Epigenetic signature and key transcriptional regulators of human antigen-specific type 1 regulatory T cells.
Cepika AM, Amaya L, Waichler C, Narula M, Mantilla MM, Thomas BC, Chen PP, Freeborn RA, Pavel-Dinu M, Nideffer J, Porteus M, Bacchetta R, Müller F, Greenleaf WJ, Chang HY, Roncarolo MG. Cepika AM, et al. Among authors: narula m. bioRxiv [Preprint]. 2024 Mar 12:2024.03.07.582969. doi: 10.1101/2024.03.07.582969. bioRxiv. 2024. PMID: 38559096 Free PMC article. Preprint.
CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells.
Goodwin M, Lee E, Lakshmanan U, Shipp S, Froessl L, Barzaghi F, Passerini L, Narula M, Sheikali A, Lee CM, Bao G, Bauer CS, Miller HK, Garcia-Lloret M, Butte MJ, Bertaina A, Shah A, Pavel-Dinu M, Hendel A, Porteus M, Roncarolo MG, Bacchetta R. Goodwin M, et al. Among authors: narula m. Sci Adv. 2020 May 6;6(19):eaaz0571. doi: 10.1126/sciadv.aaz0571. eCollection 2020 May. Sci Adv. 2020. PMID: 32494707 Free PMC article.
Photophoretic Levitation of Macroscopic Nanocardboard Plates.
Cortes J, Stanczak C, Azadi M, Narula M, Nicaise SM, Hu H, Bargatin I. Cortes J, et al. Among authors: narula m. Adv Mater. 2020 Apr;32(16):e1906878. doi: 10.1002/adma.201906878. Epub 2020 Feb 20. Adv Mater. 2020. PMID: 32080905
Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock.
Passmore MR, Byrne L, Obonyo NG, See Hoe LE, Boon AC, Diab SD, Dunster KR, Bisht K, Tung JP, Fauzi MH, Narula M, Pedersen SE, Esguerra-Lallen A, Simonova G, Sultana A, Anstey CM, Shekar K, Maitland K, Suen JY, Fraser JF. Passmore MR, et al. Among authors: narula m. Respir Res. 2018 Nov 22;19(1):231. doi: 10.1186/s12931-018-0935-4. Respir Res. 2018. PMID: 30466423 Free PMC article.
55 results