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Page 1
Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.
Lippert AH, Paluch C, Gaglioni M, Vuong MT, McColl J, Jenkins E, Fellermeyer M, Clarke J, Sharma S, Moreira da Silva S, Akkaya B, Anzilotti C, Morgan SH, Jessup CF, Körbel M, Gileadi U, Leitner J, Knox R, Chirifu M, Huo J, Yu S, Ashman N, Lui Y, Wilkinson I, Attfield KE, Fugger L, Robertson NJ, Lynch CJ, Murray L, Steinberger P, Santos AM, Lee SF, Cornall RJ, Klenerman D, Davis SJ. Lippert AH, et al. Among authors: paluch c. Immunity. 2024 Feb 13;57(2):256-270.e10. doi: 10.1016/j.immuni.2024.01.007. Immunity. 2024. PMID: 38354703 Free article.
Combination CD200R/PD-1 blockade in a humanised mouse model.
Fellermeyer M, Anzilotti C, Paluch C, Cornall RJ, Davis SJ, Gileadi U. Fellermeyer M, et al. Among authors: paluch c. Immunother Adv. 2023 Mar 30;3(1):ltad006. doi: 10.1093/immadv/ltad006. eCollection 2023. Immunother Adv. 2023. PMID: 37082107 Free PMC article.
Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation.
Kennedy A, Waters E, Rowshanravan B, Hinze C, Williams C, Janman D, Fox TA, Booth C, Pesenacker AM, Halliday N, Soskic B, Kaur S, Qureshi OS, Morris EC, Ikemizu S, Paluch C, Huo J, Davis SJ, Boucrot E, Walker LSK, Sansom DM. Kennedy A, et al. Among authors: paluch c. Nat Immunol. 2022 Sep;23(9):1365-1378. doi: 10.1038/s41590-022-01289-w. Epub 2022 Aug 23. Nat Immunol. 2022. PMID: 35999394 Free PMC article.
Immune Checkpoints as Therapeutic Targets in Autoimmunity.
Paluch C, Santos AM, Anzilotti C, Cornall RJ, Davis SJ. Paluch C, et al. Front Immunol. 2018 Oct 8;9:2306. doi: 10.3389/fimmu.2018.02306. eCollection 2018. Front Immunol. 2018. PMID: 30349540 Free PMC article. Review.