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Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity.
Flury P, Breidenbach J, Krüger N, Voget R, Schäkel L, Si Y, Krasniqi V, Calistri S, Olfert M, Sylvester K, Rocha C, Ditzinger R, Rasch A, Pöhlmann S, Kronenberger T, Poso A, Rox K, Laufer SA, Müller CE, Gütschow M, Pillaiyar T. Flury P, et al. Among authors: rocha c. ACS Pharmacol Transl Sci. 2024 Jan 19;7(2):493-514. doi: 10.1021/acsptsci.3c00313. eCollection 2024 Feb 9. ACS Pharmacol Transl Sci. 2024. PMID: 38357286
A tetravalent bispecific antibody outperforms the combination of its parental antibodies and neutralizes diverse SARS-CoV-2 variants.
Chiyyeadu A, Asgedom G, Bruhn M, Rocha C, Schlegel TU, Neumann T, Galla M, Vollmer Barbosa P, Hoffmann M, Ehrhardt K, Ha TC, Morgan M, Schoeder CT, Pöhlmann S, Kalinke U, Schambach A. Chiyyeadu A, et al. Among authors: rocha c. Clin Immunol. 2024 Mar;260:109902. doi: 10.1016/j.clim.2024.109902. Epub 2024 Jan 11. Clin Immunol. 2024. PMID: 38218210 Free article.
Filamentous fungus-produced human monoclonal antibody provides protection against SARS-CoV-2 in hamster and non-human primate models.
Kaiser FK, Hernandez MG, Krüger N, Englund E, Du W, Mykytyn AZ, Raadsen MP, Lamers MM, Rodrigues Ianiski F, Shamorkina TM, Snijder J, Armando F, Beythien G, Ciurkiewicz M, Schreiner T, Gruber-Dujardin E, Bleyer M, Batura O, Erffmeier L, Hinkel R, Rocha C, Mirolo M, Drabek D, Bosch BJ, Emalfarb M, Valbuena N, Tchelet R, Baumgärtner W, Saloheimo M, Pöhlmann S, Grosveld F, Haagmans BL, Osterhaus ADME. Kaiser FK, et al. Among authors: rocha c. Nat Commun. 2024 Mar 14;15(1):2319. doi: 10.1038/s41467-024-46443-0. Nat Commun. 2024. PMID: 38485931 Free PMC article.
Correction to "Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity".
Flury P, Breidenbach J, Krüger N, Voget R, Schäkel L, Si Y, Krasniqi V, Calistri S, Olfert M, Sylvester K, Rocha C, Ditzinger R, Rasch A, Pöhlmann S, Kronenberger T, Poso A, Rox K, Laufer SA, Müller CE, Gütschow M, Pillaiyar T. Flury P, et al. Among authors: rocha c. ACS Pharmacol Transl Sci. 2024 Mar 6;7(4):1195-1196. doi: 10.1021/acsptsci.4c00095. eCollection 2024 Apr 12. ACS Pharmacol Transl Sci. 2024. PMID: 38633592 Free article.
Omicron subvariant BA.5 efficiently infects lung cells.
Hoffmann M, Wong LR, Arora P, Zhang L, Rocha C, Odle A, Nehlmeier I, Kempf A, Richter A, Halwe NJ, Schön J, Ulrich L, Hoffmann D, Beer M, Drosten C, Perlman S, Pöhlmann S. Hoffmann M, et al. Among authors: rocha c. Nat Commun. 2023 Jun 13;14(1):3500. doi: 10.1038/s41467-023-39147-4. Nat Commun. 2023. PMID: 37311762 Free PMC article.
The role of chaperone-mediated autophagy in drug resistance.
Teixeira ABDS, Ramalho MCC, Souza I, Andrade IAM, Osawa IYA, Guedes CB, Oliveira BS, Souza Filho CHD, Silva TLD, Moreno NC, Latancia MT, Rocha CRR. Teixeira ABDS, et al. Among authors: rocha crr. Genet Mol Biol. 2024 May 31;47(Suppl 1):e20230317. doi: 10.1590/1678-4685-GMB-2023-0317. eCollection 2024. Genet Mol Biol. 2024. PMID: 38829285 Free PMC article.
1,268 results