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BCR selection and affinity maturation in Peyer's patch germinal centres.
Chen H, Zhang Y, Ye AY, Du Z, Xu M, Lee CS, Hwang JK, Kyritsis N, Ba Z, Neuberg D, Littman DR, Alt FW. Chen H, et al. Among authors: alt fw. Nature. 2020 Jun;582(7812):421-425. doi: 10.1038/s41586-020-2262-4. Epub 2020 May 6. Nature. 2020. PMID: 32499646 Free PMC article.
CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning.
Ba Z, Lou J, Ye AY, Dai HQ, Dring EW, Lin SG, Jain S, Kyritsis N, Kieffer-Kwon KR, Casellas R, Alt FW. Ba Z, et al. Among authors: alt fw. Nature. 2020 Oct;586(7828):305-310. doi: 10.1038/s41586-020-2578-0. Epub 2020 Jul 27. Nature. 2020. PMID: 32717742 Free PMC article.
Loop extrusion mediates physiological Igh locus contraction for RAG scanning.
Dai HQ, Hu H, Lou J, Ye AY, Ba Z, Zhang X, Zhang Y, Zhao L, Yoon HS, Chapdelaine-Williams AM, Kyritsis N, Chen H, Johnson K, Lin S, Conte A, Casellas R, Lee CS, Alt FW. Dai HQ, et al. Among authors: alt fw. Nature. 2021 Feb;590(7845):338-343. doi: 10.1038/s41586-020-03121-7. Epub 2021 Jan 13. Nature. 2021. PMID: 33442057 Free PMC article.
Ku70 suppresses alternative end joining in G1-arrested progenitor B cells.
Liang Z, Kumar V, Le Bouteiller M, Zurita J, Kenrick J, Lin SG, Lou J, Hu J, Ye AY, Boboila C, Alt FW, Frock RL. Liang Z, et al. Among authors: alt fw. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2103630118. doi: 10.1073/pnas.2103630118. Proc Natl Acad Sci U S A. 2021. PMID: 34006647 Free PMC article.
An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion.
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW. Luo S, et al. Among authors: alt fw. Sci Immunol. 2022 Oct 28;7(76):eadd5446. doi: 10.1126/sciimmunol.add5446. Epub 2022 Aug 11. Sci Immunol. 2022. PMID: 35951767 Free PMC article.
527 results