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SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations.
Lustig G, Ganga Y, Rodel HE, Tegally H, Khairallah A, Jackson L, Cele S, Khan K, Jule Z, Reedoy K, Karim F, Bernstein M, Ndung'u T, Moosa MS, Archary D, de Oliveira T, Lessells R, Neher RA, Abdool Karim SS, Sigal A. Lustig G, et al. Among authors: moosa ms. Virus Evol. 2023 Dec 28;10(1):vead075. doi: 10.1093/ve/vead075. eCollection 2024. Virus Evol. 2023. PMID: 38361824 Free PMC article.
Individuals with HIV-1 Subtype C Infection and Cryptococcal Meningitis Exhibit Viral Genetic Intermixing of HIV-1 Between Plasma and Cerebrospinal Fluid and a High Prevalence of CXCR4-Using Variants.
Sojane K, Kangethe RT, Chang CC, Moosa MS, Lewin SR, French MA, Ndung'u T. Sojane K, et al. Among authors: moosa ms. AIDS Res Hum Retroviruses. 2018 Jul;34(7):607-620. doi: 10.1089/AID.2017.0209. Epub 2018 May 23. AIDS Res Hum Retroviruses. 2018. PMID: 29658309 Free PMC article.
Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome Is Associated With Dysregulation of IL-7/IL-7 Receptor Signaling Pathway in T Cells and Monocyte Activation.
Akilimali NA, Muema DM, Specht C, Chang CC, Moosa MS, Levitz SM, Lewin SR, French MA, Ndungʼu T. Akilimali NA, et al. Among authors: moosa ms. J Acquir Immune Defic Syndr. 2019 Apr 15;80(5):596-604. doi: 10.1097/QAI.0000000000001946. J Acquir Immune Defic Syndr. 2019. PMID: 30649031 Free PMC article.
Increased Neutrophil Count and Decreased Neutrophil CD15 Expression Correlate With TB Disease Severity and Treatment Response Irrespective of HIV Co-infection.
Ndlovu LN, Peetluk L, Moodley S, Nhamoyebonde S, Ngoepe AT, Mazibuko M, Khan K, Karim F, Pym AS, Maruri F, Moosa MS, van der Heijden YF, Sterling TR, Leslie A. Ndlovu LN, et al. Among authors: moosa ms. Front Immunol. 2020 Aug 28;11:1872. doi: 10.3389/fimmu.2020.01872. eCollection 2020. Front Immunol. 2020. PMID: 32983107 Free PMC article.
Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma.
Cele S, Gazy I, Jackson L, Hwa SH, Tegally H, Lustig G, Giandhari J, Pillay S, Wilkinson E, Naidoo Y, Karim F, Ganga Y, Khan K, Bernstein M, Balazs AB, Gosnell BI, Hanekom W, Moosa MS; Network for Genomic Surveillance in South Africa; COMMIT-KZN Team; Lessells RJ, de Oliveira T, Sigal A. Cele S, et al. Among authors: moosa ms. Nature. 2021 May;593(7857):142-146. doi: 10.1038/s41586-021-03471-w. Epub 2021 Mar 29. Nature. 2021. PMID: 33780970 Free PMC article.
T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy.
Lustig G, Cele S, Karim F, Derache A, Ngoepe A, Khan K, Gosnell BI, Moosa MS, Ntshuba N, Marais S, Jeena PM, Govender K, Adamson J, Kløverpris H, Gupta RK, Harrichandparsad R, Patel VB, Sigal A. Lustig G, et al. Among authors: moosa ms. PLoS Pathog. 2021 Sep 23;17(9):e1009871. doi: 10.1371/journal.ppat.1009871. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34555123 Free PMC article.
HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave.
Karim F, Gazy I, Cele S, Zungu Y, Krause R, Bernstein M, Khan K, Ganga Y, Rodel H, Mthabela N, Mazibuko M, Muema D, Ramjit D, Ndung'u T, Hanekom W, Gosnell B; COMMIT-KZN Team; Lessells RJ, Wong EB, de Oliveira T, Moosa MS, Lustig G, Leslie A, Kløverpris H, Sigal A. Karim F, et al. Among authors: moosa ms. Elife. 2021 Oct 5;10:e67397. doi: 10.7554/eLife.67397. Elife. 2021. PMID: 34608862 Free PMC article.
Immunogenicity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Ad26.CoV2.S Vaccination in People Living With Human Immunodeficiency Virus (HIV).
Khan K, Lustig G, Bernstein M, Archary D, Cele S, Karim F, Smith M, Ganga Y, Jule Z, Reedoy K, Miya Y, Mthabela N, Magula NP, Lessells R, de Oliveira T, Gosnell BI, Abdool Karim S, Garrett N, Hanekom W, Bekker LG, Gray G, Blackburn JM, Moosa MS, Sigal A; COMMIT-KZN Team. Khan K, et al. Among authors: moosa ms. Clin Infect Dis. 2022 Aug 24;75(1):e857-e864. doi: 10.1093/cid/ciab1008. Clin Infect Dis. 2022. PMID: 34893824 Free PMC article.
SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection.
Cele S, Jackson L, Khoury DS, Khan K, Moyo-Gwete T, Tegally H, San JE, Cromer D, Scheepers C, Amoako D, Karim F, Bernstein M, Lustig G, Archary D, Smith M, Ganga Y, Jule Z, Reedoy K, Hwa SH, Giandhari J, Blackburn JM, Gosnell BI, Abdool Karim SS, Hanekom W; NGS-SA; COMMIT-KZN Team; von Gottberg A, Bhiman J, Lessells RJ, Moosa MS, Davenport MP, de Oliveira T, Moore PL, Sigal A. Cele S, et al. Among authors: moosa ms. medRxiv [Preprint]. 2021 Dec 17:2021.12.08.21267417. doi: 10.1101/2021.12.08.21267417. medRxiv. 2021. PMID: 34909788 Free PMC article. Updated. Preprint.
63 results