Hwang JY - Search Results

1

Carrillo AK, Kadayat TM, Hwang JY, Chen Y, Zhu F, Holbrook G, Gillingwater K, Connelly MC, Yang L, Kaiser M, Guy RK. Carrillo AK, et al. Among authors: hwang jy. J Med Chem. 2024 Mar 14;67(5):3437-3447. doi: 10.1021/acs.jmedchem.3c01680. Epub 2024 Feb 16. J Med Chem. 2024. PMID: 38363074

2

Optimization of chloronitrobenzamides (CNBs) as therapeutic leads for human African trypanosomiasis (HAT).

Hwang JY, Smithson D, Zhu F, Holbrook G, Connelly MC, Kaiser M, Brun R, Guy RK. Hwang JY, et al. J Med Chem. 2013 Apr 11;56(7):2850-60. doi: 10.1021/jm301687p. Epub 2013 Mar 26. J Med Chem. 2013. PMID: 23484493

3

Optimization of the electrophile of chloronitrobenzamide leads active against Trypanosoma brucei.

Hwang JY, Smithson DC, Holbrook G, Zhu F, Connelly MC, Kaiser M, Brun R, Kiplin Guy R. Hwang JY, et al. Bioorg Med Chem Lett. 2013 Jul 15;23(14):4127-31. doi: 10.1016/j.bmcl.2013.05.049. Epub 2013 May 23. Bioorg Med Chem Lett. 2013. PMID: 23746473

4

Improvement of pharmacological properties of irreversible thyroid receptor coactivator binding inhibitors.

Hwang JY, Arnold LA, Zhu F, Kosinski A, Mangano TJ, Setola V, Roth BL, Guy RK. Hwang JY, et al. J Med Chem. 2009 Jul 9;52(13):3892-901. doi: 10.1021/jm9002704. J Med Chem. 2009. PMID: 19469546 Free PMC article.

5

Discovery of halo-nitrobenzamides with potential application against human African trypanosomiasis.

Hwang JY, Smithson D, Connelly M, Maier J, Zhu F, Guy KR. Hwang JY, et al. Bioorg Med Chem Lett. 2010 Jan 1;20(1):149-52. doi: 10.1016/j.bmcl.2009.11.022. Epub 2009 Nov 14. Bioorg Med Chem Lett. 2010. PMID: 19963377

6

Synthesis and evaluation of 7-substituted 4-aminoquinoline analogues for antimalarial activity.

Hwang JY, Kawasuji T, Lowes DJ, Clark JA, Connelly MC, Zhu F, Guiguemde WA, Sigal MS, Wilson EB, Derisi JL, Guy RK. Hwang JY, et al. J Med Chem. 2011 Oct 27;54(20):7084-93. doi: 10.1021/jm200636z. Epub 2011 Sep 26. J Med Chem. 2011. PMID: 21910466 Free PMC article.

7

Synthesis and evaluation of methylsulfonylnitrobenzamides (MSNBAs) as inhibitors of the thyroid hormone receptor-coactivator interaction.

Hwang JY, Attia RR, Carrillo AK, Connelly MC, Guy RK. Hwang JY, et al. Bioorg Med Chem Lett. 2013 Mar 15;23(6):1891-5. doi: 10.1016/j.bmcl.2012.12.055. Epub 2013 Jan 8. Bioorg Med Chem Lett. 2013. PMID: 23414840 Free PMC article.

8

Methylsulfonylnitrobenzoates, a new class of irreversible inhibitors of the interaction of the thyroid hormone receptor and its obligate coactivators that functionally antagonizes thyroid hormone.

Hwang JY, Huang W, Arnold LA, Huang R, Attia RR, Connelly M, Wichterman J, Zhu F, Augustinaite I, Austin CP, Inglese J, Johnson RL, Guy RK. Hwang JY, et al. J Biol Chem. 2011 Apr 8;286(14):11895-908. doi: 10.1074/jbc.M110.200436. Epub 2011 Feb 14. J Biol Chem. 2011. PMID: 21321127 Free PMC article.

9

Synthesis and evaluation of sulfonylnitrophenylthiazoles (SNPTs) as thyroid hormone receptor-coactivator interaction inhibitors.

Hwang JY, Attia RR, Zhu F, Yang L, Lemoff A, Jeffries C, Connelly MC, Guy RK. Hwang JY, et al. J Med Chem. 2012 Mar 8;55(5):2301-10. doi: 10.1021/jm201546m. Epub 2012 Feb 23. J Med Chem. 2012. PMID: 22324546 Free PMC article.

10

Similarities and differences between two modes of antagonism of the thyroid hormone receptor.

Sadana P, Hwang JY, Attia RR, Arnold LA, Neale G, Guy RK. Sadana P, et al. Among authors: hwang jy. ACS Chem Biol. 2011 Oct 21;6(10):1096-106. doi: 10.1021/cb200092v. Epub 2011 Aug 15. ACS Chem Biol. 2011. PMID: 21815645 Free PMC article.

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