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Pharmacokinetic-Pharmacodynamic Modelling in Hemophilia A: Relating Thrombin and Plasmin Generation to Factor VIII Activity After Administration of a VWF/FVIII Concentrate.
Valke LLFG, Cloesmeijer ME, Mansouritorghabeh H, Barteling W, Blijlevens NMA, Cnossen MH, Mathôt RAA, Schols SEM, van Heerde WL. Valke LLFG, et al. Eur J Drug Metab Pharmacokinet. 2024 Mar;49(2):191-205. doi: 10.1007/s13318-024-00876-6. Epub 2024 Feb 17. Eur J Drug Metab Pharmacokinet. 2024. PMID: 38367175 Free PMC article.
The Nijmegen ultra-sensitive Bethesda Assay detects very low-titer factor VIII inhibitors in patients with congenital and acquired hemophilia A.
Valke LLFG, Verhagen MJA, Mulders BTPM, Polenewen R, Blijlevens NMA, Jansen JH, Mansouritorghabeh H, Elsheikh E, Reipert BM, Turecek PL, O'Donnell JS, Rijpma SR, Schols SEM, van Heerde WL, Meijer D. Valke LLFG, et al. Thromb Res. 2023 Nov;231:112-120. doi: 10.1016/j.thromres.2023.10.007. Epub 2023 Oct 11. Thromb Res. 2023. PMID: 37844518
Combining factor VIII levels and thrombin/plasmin generation: A population pharmacokinetic-pharmacodynamic model for patients with haemophilia A.
Bukkems LH, Valke LLFG, Barteling W, Laros-van Gorkom BAP, Blijlevens NMA, Cnossen MH, van Heerde WL, Schols SEM, Mathôt RAA. Bukkems LH, et al. Among authors: valke llfg. Br J Clin Pharmacol. 2022 Jun;88(6):2757-2768. doi: 10.1111/bcp.15185. Epub 2022 Jan 15. Br J Clin Pharmacol. 2022. PMID: 34921439 Free PMC article.
12 results