Lee JD - Search Results

1

A transient protein folding response targets aggregation in the early phase of TDP-43-mediated neurodegeneration.

San Gil R, Pascovici D, Venturato J, Brown-Wright H, Mehta P, Madrid San Martin L, Wu J, Luan W, Chui YK, Bademosi AT, Swaminathan S, Naidoo S, Berning BA, Wright AL, Keating SS, Curtis MA, Faull RLM, Lee JD, Ngo ST, Lee A, Morsch M, Chung RS, Scotter E, Lisowski L, Mirzaei M, Walker AK. San Gil R, et al. Among authors: lee jd, lee a. Nat Commun. 2024 Feb 19;15(1):1508. doi: 10.1038/s41467-024-45646-9. Nat Commun. 2024. PMID: 38374041 Free PMC article.

2

Impairments to the GH-IGF-I axis in hSOD1G93A mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis.

Steyn FJ, Ngo ST, Lee JD, Leong JW, Buckley AJ, Veldhuis JD, McCombe PA, Chen C, Bellingham MC. Steyn FJ, et al. Among authors: lee jd. Endocrinology. 2012 Aug;153(8):3735-46. doi: 10.1210/en.2011-2171. Epub 2012 May 23. Endocrinology. 2012. PMID: 22621959

3

Cortical synaptic and dendritic spine abnormalities in a presymptomatic TDP-43 model of amyotrophic lateral sclerosis.

Fogarty MJ, Klenowski PM, Lee JD, Drieberg-Thompson JR, Bartlett SE, Ngo ST, Hilliard MA, Bellingham MC, Noakes PG. Fogarty MJ, et al. Among authors: lee jd. Sci Rep. 2016 Nov 29;6:37968. doi: 10.1038/srep37968. Sci Rep. 2016. PMID: 27897242 Free PMC article.

4

Gut microbiota in ALS: possible role in pathogenesis?

McCombe PA, Henderson RD, Lee A, Lee JD, Woodruff TM, Restuadi R, McRae A, Wray NR, Ngo S, Steyn FJ. McCombe PA, et al. Among authors: lee jd, lee a. Expert Rev Neurother. 2019 Sep;19(9):785-805. doi: 10.1080/14737175.2019.1623026. Epub 2019 May 29. Expert Rev Neurother. 2019. PMID: 31122082 Review.

5

Defects in synaptic transmission at the neuromuscular junction precede motor deficits in a TDP-43^Q331K transgenic mouse model of amyotrophic lateral sclerosis.

Chand KK, Lee KM, Lee JD, Qiu H, Willis EF, Lavidis NA, Hilliard MA, Noakes PG. Chand KK, et al. Among authors: lee jd, lee km. FASEB J. 2018 May;32(5):2676-2689. doi: 10.1096/fj.201700835R. Epub 2018 Jan 2. FASEB J. 2018. PMID: 29295857

6

Complement components are upregulated and correlate with disease progression in the TDP-43^Q331K mouse model of amyotrophic lateral sclerosis.

Lee JD, Levin SC, Willis EF, Li R, Woodruff TM, Noakes PG. Lee JD, et al. J Neuroinflammation. 2018 Jun 1;15(1):171. doi: 10.1186/s12974-018-1217-2. J Neuroinflammation. 2018. PMID: 29859100 Free PMC article.

7

TDP-43 Puts the STING in ALS.

Lee JD, Woodruff TM. Lee JD, et al. Trends Neurosci. 2021 Feb;44(2):81-82. doi: 10.1016/j.tins.2020.12.001. Epub 2020 Dec 20. Trends Neurosci. 2021. PMID: 33353765

8

Therapeutic blockade of HMGB1 reduces early motor deficits, but not survival in the SOD1^G93A mouse model of amyotrophic lateral sclerosis.

Lee JD, Liu N, Levin SC, Ottosson L, Andersson U, Harris HE, Woodruff TM. Lee JD, et al. J Neuroinflammation. 2019 Feb 19;16(1):45. doi: 10.1186/s12974-019-1435-2. J Neuroinflammation. 2019. PMID: 30782181 Free PMC article.

9

Revisiting the role of the innate immune complement system in ALS.

Parker SE, Hanton AM, Stefanou SN, Noakes PG, Woodruff TM, Lee JD. Parker SE, et al. Among authors: lee jd. Neurobiol Dis. 2019 Jul;127:223-232. doi: 10.1016/j.nbd.2019.03.003. Epub 2019 Mar 6. Neurobiol Dis. 2019. PMID: 30849511 Review.

10

Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1^G93A Mouse Model of Amyotrophic Lateral Sclerosis.

Lee JD, McDonald TS, Fung JNT, Woodruff TM. Lee JD, et al. Mol Neurobiol. 2020 Oct;57(10):4143-4155. doi: 10.1007/s12035-020-02019-9. Epub 2020 Jul 16. Mol Neurobiol. 2020. PMID: 32676989

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