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Comparative Immunogenomics of Canine Natural Killer Cells as Immunotherapy Target.
Gingrich AA, Reiter TE, Judge SJ, York D, Yanagisawa M, Razmara A, Sturgill I, Basmaci UN, Brady RV, Stoffel K, Murphy WJ, Rebhun RB, Brown CT, Canter RJ. Gingrich AA, et al. Front Immunol. 2021 Sep 14;12:670309. doi: 10.3389/fimmu.2021.670309. eCollection 2021. Front Immunol. 2021. PMID: 34594320 Free PMC article.
Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer.
Judge SJ, Yanagisawa M, Sturgill IR, Bateni SB, Gingrich AA, Foltz JA, Lee DA, Modiano JF, Monjazeb AM, Culp WTN, Rebhun RB, Murphy WJ, Kent MS, Canter RJ. Judge SJ, et al. Among authors: gingrich aa. PLoS One. 2020 Feb 21;15(2):e0224775. doi: 10.1371/journal.pone.0224775. eCollection 2020. PLoS One. 2020. PMID: 32084139 Free PMC article. Clinical Trial.
Analysis of tumor-infiltrating NK and T cells highlights IL-15 stimulation and TIGIT blockade as a combination immunotherapy strategy for soft tissue sarcomas.
Judge SJ, Darrow MA, Thorpe SW, Gingrich AA, O'Donnell EF, Bellini AR, Sturgill IR, Vick LV, Dunai C, Stoffel KM, Lyu Y, Chen S, Cho M, Rebhun RB, Monjazeb AM, Murphy WJ, Canter RJ. Judge SJ, et al. Among authors: gingrich aa. J Immunother Cancer. 2020 Nov;8(2):e001355. doi: 10.1136/jitc-2020-001355. J Immunother Cancer. 2020. PMID: 33158916 Free PMC article.
Inhaled recombinant human IL-15 in dogs with naturally occurring pulmonary metastases from osteosarcoma or melanoma: a phase 1 study of clinical activity and correlates of response.
Rebhun RB, York D, Cruz SM, Judge SJ, Razmara AM, Farley LE, Brady RV, Johnson EG, Burton JH, Willcox J, Wittenburg LA, Woolard K, Dunai C, Stewart SL, Sparger EE, Withers SS, Gingrich AA, Skorupski KA, Al-Nadaf S, LeJeune AT, Culp WT, Murphy WJ, Kent MS, Canter RJ. Rebhun RB, et al. Among authors: gingrich aa. J Immunother Cancer. 2022 Jun;10(6):e004493. doi: 10.1136/jitc-2022-004493. J Immunother Cancer. 2022. PMID: 35680383 Free PMC article. Clinical Trial.
Intratumoral NKp46+ natural killer cells are spatially distanced from T and MHC-I+ cells with prognostic implications in soft tissue sarcoma.
Cruz SM, Sholevar CJ, Judge SJ, Darrow MA, Iranpur KR, Farley LE, Lammers M, Razmara AM, Dunai C, Gingrich AA, Persky J, Mori H, Thorpe SW, Monjazeb AM, Murphy WJ, Canter RJ. Cruz SM, et al. Among authors: gingrich aa. Front Immunol. 2023 Jul 21;14:1230534. doi: 10.3389/fimmu.2023.1230534. eCollection 2023. Front Immunol. 2023. PMID: 37545516 Free PMC article.
Human soft tissue sarcomas harbor an intratumoral viral microbiome which is linked with natural killer cell infiltrate and prognosis.
Perry LM, Cruz SM, Kleber KT, Judge SJ, Darrow MA, Jones LB, Basmaci UN, Joshi N, Settles ML, Durbin-Johnson BP, Gingrich AA, Monjazeb AM, Carr-Ascher J, Thorpe SW, Murphy WJ, Eisen JA, Canter RJ. Perry LM, et al. Among authors: gingrich aa. J Immunother Cancer. 2023 Jan;11(1):e004285. doi: 10.1136/jitc-2021-004285. J Immunother Cancer. 2023. PMID: 36599469 Free PMC article.
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