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Tropomyosin-troponin complex in inherited cardiomyopathies.
Juárez CK, Sequeira V, van den Boogaard M, Veerman CC, Hoetjes NJ, Poel E, Tanck MWT, Lekanne Deprez RH, Vermeer AMC, van der Velden J, Amin AS. Juárez CK, et al. Among authors: van den boogaard m, van der velden j. Heart Rhythm. 2024 Feb 19:S1547-5271(24)00206-6. doi: 10.1016/j.hrthm.2024.02.034. Online ahead of print. Heart Rhythm. 2024. PMID: 38382684 Free article. No abstract available.
Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations.
Sequeira V, Wijnker PJ, Nijenkamp LL, Kuster DW, Najafi A, Witjas-Paalberends ER, Regan JA, Boontje N, Ten Cate FJ, Germans T, Carrier L, Sadayappan S, van Slegtenhorst MA, Zaremba R, Foster DB, Murphy AM, Poggesi C, Dos Remedios C, Stienen GJ, Ho CY, Michels M, van der Velden J. Sequeira V, et al. Among authors: van slegtenhorst ma, van der velden j. Circ Res. 2013 May 24;112(11):1491-505. doi: 10.1161/CIRCRESAHA.111.300436. Epub 2013 Mar 18. Circ Res. 2013. PMID: 23508784 Free PMC article.
PKCα-specific phosphorylation of the troponin complex in human myocardium: a functional and proteomics analysis.
Kooij V, Zhang P, Piersma SR, Sequeira V, Boontje NM, Wijnker PJ, Jiménez CR, Jaquet KE, dos Remedios C, Murphy AM, Van Eyk JE, van der Velden J, Stienen GJ. Kooij V, et al. Among authors: van eyk je, van der velden j. PLoS One. 2013 Oct 7;8(10):e74847. doi: 10.1371/journal.pone.0074847. eCollection 2013. PLoS One. 2013. PMID: 24116014 Free PMC article.
Length-dependent activation is modulated by cardiac troponin I bisphosphorylation at Ser23 and Ser24 but not by Thr143 phosphorylation.
Wijnker PJ, Sequeira V, Foster DB, Li Y, Dos Remedios CG, Murphy AM, Stienen GJ, van der Velden J. Wijnker PJ, et al. Among authors: van der velden j. Am J Physiol Heart Circ Physiol. 2014 Apr 15;306(8):H1171-81. doi: 10.1152/ajpheart.00580.2013. Epub 2014 Feb 28. Am J Physiol Heart Circ Physiol. 2014. PMID: 24585778 Free PMC article.
Phosphorylation of protein kinase C sites Ser42/44 decreases Ca(2+)-sensitivity and blunts enhanced length-dependent activation in response to protein kinase A in human cardiomyocytes.
Wijnker PJ, Sequeira V, Witjas-Paalberends ER, Foster DB, dos Remedios CG, Murphy AM, Stienen GJ, van der Velden J. Wijnker PJ, et al. Among authors: van der velden j. Arch Biochem Biophys. 2014 Jul 15;554:11-21. doi: 10.1016/j.abb.2014.04.017. Epub 2014 May 9. Arch Biochem Biophys. 2014. PMID: 24814372 Free PMC article.
Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations.
Witjas-Paalberends ER, Güçlü A, Germans T, Knaapen P, Harms HJ, Vermeer AM, Christiaans I, Wilde AA, Dos Remedios C, Lammertsma AA, van Rossum AC, Stienen GJ, van Slegtenhorst M, Schinkel AF, Michels M, Ho CY, Poggesi C, van der Velden J. Witjas-Paalberends ER, et al. Among authors: van rossum ac, van slegtenhorst m, van der velden j. Cardiovasc Res. 2014 Jul 15;103(2):248-57. doi: 10.1093/cvr/cvu127. Epub 2014 May 16. Cardiovasc Res. 2014. PMID: 24835277
612 results