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The cycad genotoxin methylazoxymethanol, linked to Guam ALS/PDC, induces transcriptional mutagenesis.
Verheijen BM, Chung C, Thompson B, Kim H, Nakahara A, Anink JJ, Mills JD; NYGC ALS Consortium; Lee JH, Aronica E, Oyanagi K, Kakita A, Gout JF, Vermulst M. Verheijen BM, et al. Among authors: lee jh. Acta Neuropathol Commun. 2024 Feb 21;12(1):30. doi: 10.1186/s40478-024-01725-y. Acta Neuropathol Commun. 2024. PMID: 38383591 Free PMC article. No abstract available.
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A.
Brown AL, Wilkins OG, Keuss MJ, Hill SE, Zanovello M, Lee WC, Bampton A, Lee FCY, Masino L, Qi YA, Bryce-Smith S, Gatt A, Hallegger M, Fagegaltier D, Phatnani H; NYGC ALS Consortium; Newcombe J, Gustavsson EK, Seddighi S, Reyes JF, Coon SL, Ramos D, Schiavo G, Fisher EMC, Raj T, Secrier M, Lashley T, Ule J, Buratti E, Humphrey J, Ward ME, Fratta P. Brown AL, et al. Nature. 2022 Mar;603(7899):131-137. doi: 10.1038/s41586-022-04436-3. Epub 2022 Feb 23. Nature. 2022. PMID: 35197628 Free PMC article.
A Multimodal Ensemble Deep Learning Model for Functional Outcome Prognosis of Stroke Patients.
Jung HS, Lee EJ, Chang DI, Cho HJ, Lee J, Cha JK, Park MS, Yu KH, Jung JM, Ahn SH, Kim DE, Lee JH, Hong KS, Sohn SI, Park KP, Kwon SU, Kim JS, Chang JY, Kim BJ, Kang DW; KOSNI Investigators. Jung HS, et al. Among authors: lee jh. J Stroke. 2024 May;26(2):312-320. doi: 10.5853/jos.2023.03426. Epub 2024 May 30. J Stroke. 2024. PMID: 38836278
Engineered Exosomes Containing microRNA-29b-2 and Targeting the Somatostatin Receptor Reduce Presenilin 1 Expression and Decrease the β-Amyloid Accumulation in the Brains of Mice with Alzheimer's Disease.
Lin EY, Hsu SX, Wu BH, Deng YC, Wuli W, Li YS, Lee JH, Lin SZ, Harn HJ, Chiou TW. Lin EY, et al. Among authors: lee jh. Int J Nanomedicine. 2024 May 29;19:4977-4994. doi: 10.2147/IJN.S442876. eCollection 2024. Int J Nanomedicine. 2024. PMID: 38828204 Free PMC article.
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