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Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
Altman PX, Ozorowski G, Stanfield RL, Haakenson J, Appel M, Parren M, Lee WH, Sang H, Woehl J, Saye-Francisco K, Joyce C, Song G, Porter K, Landais E, Andrabi R, Wilson IA, Ward AB, Mwangi W, Smider VV, Burton DR, Sok D. Altman PX, et al. Among authors: haakenson j. bioRxiv [Preprint]. 2024 Feb 14:2024.02.13.580058. doi: 10.1101/2024.02.13.580058. bioRxiv. 2024. PMID: 38405899 Free PMC article. Preprint.
Evolution of immunogenetic components encoding ultralong CDR H3.
Ott JA, Mitchell C, Sheppard M, Deiss TC, Horton JMC, Haakenson JK, Huang R, Kelley AR, Davis BW, Derr JN, Smider VV, Criscitiello MF. Ott JA, et al. Among authors: haakenson jk. Immunogenetics. 2023 Aug;75(4):323-339. doi: 10.1007/s00251-023-01305-9. Epub 2023 Apr 21. Immunogenetics. 2023. PMID: 37084012 Free PMC article.
A Broad Role for Cysteines in Bovine Antibody Diversity.
Haakenson JK, Deiss TC, Warner GF, Mwangi W, Criscitiello MF, Smider VV. Haakenson JK, et al. Immunohorizons. 2019 Oct 16;3(10):478-487. doi: 10.4049/immunohorizons.1900058. Immunohorizons. 2019. PMID: 31619454 Free PMC article.
HDAC6 regulates DNA damage response via deacetylating MLH1.
Zhang M, Hu C, Moses N, Haakenson J, Xiang S, Quan D, Fang B, Yang Z, Bai W, Bepler G, Li GM, Zhang XM. Zhang M, et al. Among authors: haakenson j. J Biol Chem. 2019 Apr 12;294(15):5813-5826. doi: 10.1074/jbc.RA118.006374. Epub 2019 Feb 15. J Biol Chem. 2019. PMID: 30770470 Free PMC article.
Diversity in the Cow Ultralong CDR H3 Antibody Repertoire.
Haakenson JK, Huang R, Smider VV. Haakenson JK, et al. Front Immunol. 2018 Jun 4;9:1262. doi: 10.3389/fimmu.2018.01262. eCollection 2018. Front Immunol. 2018. PMID: 29915599 Free PMC article. Review.
The Unusual Genetics and Biochemistry of Bovine Immunoglobulins.
Stanfield RL, Haakenson J, Deiss TC, Criscitiello MF, Wilson IA, Smider VV. Stanfield RL, et al. Among authors: haakenson j. Adv Immunol. 2018;137:135-164. doi: 10.1016/bs.ai.2017.12.004. Epub 2018 Feb 9. Adv Immunol. 2018. PMID: 29455846 Free PMC article.
HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα.
Zhang M, Xiang S, Joo HY, Wang L, Williams KA, Liu W, Hu C, Tong D, Haakenson J, Wang C, Zhang S, Pavlovicz RE, Jones A, Schmidt KH, Tang J, Dong H, Shan B, Fang B, Radhakrishnan R, Glazer PM, Matthias P, Koomen J, Seto E, Bepler G, Nicosia SV, Chen J, Li C, Gu L, Li GM, Bai W, Wang H, Zhang X. Zhang M, et al. Among authors: haakenson j. Mol Cell. 2014 Jul 3;55(1):31-46. doi: 10.1016/j.molcel.2014.04.028. Epub 2014 May 29. Mol Cell. 2014. PMID: 24882211 Free PMC article.
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