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Glioblastoma-infiltrating CD8+ T cells are predominantly a clonally expanded GZMK+ effector population.
Wang AZ, Mashimo BL, Schaettler MO, Sherpa ND, Leavitt LA, Livingstone AJ, Khan SM, Li M, Anzaldua-Campos MI, Bradley JD, Leuthardt EC, Kim AH, Dowling JL, Chicoine MR, Jones PS, Choi BD, Cahill DP, Carter BS, Petti AA, Johanns TM, Dunn GP. Wang AZ, et al. Among authors: choi bd. Cancer Discov. 2024 Feb 28. doi: 10.1158/2159-8290.CD-23-0913. Online ahead of print. Cancer Discov. 2024. PMID: 38416133
CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity.
Choi BD, Yu X, Castano AP, Bouffard AA, Schmidts A, Larson RC, Bailey SR, Boroughs AC, Frigault MJ, Leick MB, Scarfò I, Cetrulo CL, Demehri S, Nahed BV, Cahill DP, Wakimoto H, Curry WT, Carter BS, Maus MV. Choi BD, et al. Nat Biotechnol. 2019 Sep;37(9):1049-1058. doi: 10.1038/s41587-019-0192-1. Epub 2019 Jul 22. Nat Biotechnol. 2019. PMID: 31332324
CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma.
Choi BD, Yu X, Castano AP, Darr H, Henderson DB, Bouffard AA, Larson RC, Scarfò I, Bailey SR, Gerhard GM, Frigault MJ, Leick MB, Schmidts A, Sagert JG, Curry WT, Carter BS, Maus MV. Choi BD, et al. J Immunother Cancer. 2019 Nov 14;7(1):304. doi: 10.1186/s40425-019-0806-7. J Immunother Cancer. 2019. PMID: 31727131 Free PMC article.
Immune Therapy for Central Nervous System Metastasis.
McAvoy MB, Choi BD, Jones PS. McAvoy MB, et al. Among authors: choi bd. Neurosurg Clin N Am. 2020 Oct;31(4):627-639. doi: 10.1016/j.nec.2020.06.014. Epub 2020 Aug 15. Neurosurg Clin N Am. 2020. PMID: 32921357 Review.
IDH-mutant gliomas harbor fewer regulatory T cells in humans and mice.
Richardson LG, Nieman LT, Stemmer-Rachamimov AO, Zheng XS, Stafford K, Nagashima H, Miller JJ, Kiyokawa J, Ting DT, Wakimoto H, Cahill DP, Choi BD, Curry WT. Richardson LG, et al. Among authors: choi bd. Oncoimmunology. 2020 Aug 20;9(1):1806662. doi: 10.1080/2162402X.2020.1806662. Oncoimmunology. 2020. PMID: 32923170 Free PMC article.
141 results