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Glioblastoma-infiltrating CD8+ T cells are predominantly a clonally expanded GZMK+ effector population.
Wang AZ, Mashimo BL, Schaettler MO, Sherpa ND, Leavitt LA, Livingstone AJ, Khan SM, Li M, Anzaldua-Campos MI, Bradley JD, Leuthardt EC, Kim AH, Dowling JL, Chicoine MR, Jones PS, Choi BD, Cahill DP, Carter BS, Petti AA, Johanns TM, Dunn GP. Wang AZ, et al. Among authors: leuthardt ec. Cancer Discov. 2024 Feb 28. doi: 10.1158/2159-8290.CD-23-0913. Online ahead of print. Cancer Discov. 2024. PMID: 38416133
Characterization of the Genomic and Immunologic Diversity of Malignant Brain Tumors through Multisector Analysis.
Schaettler MO, Richters MM, Wang AZ, Skidmore ZL, Fisk B, Miller KE, Vickery TL, Kim AH, Chicoine MR, Osbun JW, Leuthardt EC, Dowling JL, Zipfel GJ, Dacey RG, Lu HC, Johanns TM, Griffith OL, Mardis ER, Griffith M, Dunn GP. Schaettler MO, et al. Among authors: leuthardt ec. Cancer Discov. 2022 Jan;12(1):154-171. doi: 10.1158/2159-8290.CD-21-0291. Epub 2021 Oct 5. Cancer Discov. 2022. PMID: 34610950 Free PMC article.
Single-cell profiling of human dura and meningioma reveals cellular meningeal landscape and insights into meningioma immune response.
Wang AZ, Bowman-Kirigin JA, Desai R, Kang LI, Patel PR, Patel B, Khan SM, Bender D, Marlin MC, Liu J, Osbun JW, Leuthardt EC, Chicoine MR, Dacey RG Jr, Zipfel GJ, Kim AH, DeNardo DG, Petti AA, Dunn GP. Wang AZ, et al. Among authors: leuthardt ec. Genome Med. 2022 May 10;14(1):49. doi: 10.1186/s13073-022-01051-9. Genome Med. 2022. PMID: 35534852 Free PMC article.
The Conventional Dendritic Cell 1 Subset Primes CD8+ T Cells and Traffics Tumor Antigen to Drive Antitumor Immunity in the Brain.
Bowman-Kirigin JA, Desai R, Saunders BT, Wang AZ, Schaettler MO, Liu CJ, Livingstone AJ, Kobayashi DK, Durai V, Kretzer NM, Zipfel GJ, Leuthardt EC, Osbun JW, Chicoine MR, Kim AH, Murphy KM, Johanns TM, Zinselmeyer BH, Dunn GP. Bowman-Kirigin JA, et al. Among authors: leuthardt ec. Cancer Immunol Res. 2023 Jan 3;11(1):20-37. doi: 10.1158/2326-6066.CIR-22-0098. Cancer Immunol Res. 2023. PMID: 36409838 Free PMC article.
Multivariate analysis of associations between clinical sequencing and outcome in glioblastoma.
Yang PH, Tao Y, Luo J, Paturu M, Lu HC, Ramkissoon S, Heusel JW, Leuthardt EC, Chicoine MR, Dowling JL, Dunn GP, Duncavage E, Dahiya S, Chattherjee AR, Kim AH. Yang PH, et al. Among authors: leuthardt ec. Neurooncol Adv. 2022 Jan 10;4(1):vdac002. doi: 10.1093/noajnl/vdac002. eCollection 2022 Jan-Dec. Neurooncol Adv. 2022. PMID: 35156038 Free PMC article.
A pilot study of lymphoscintigraphy with tracer injection into the human brain.
Coxon AT, Desai R, Patel PR, Vellimana AK, Willie JT, Dowling JL, Leuthardt EC, Kim AH, Johanns TM, Siegel BA, Dunn GP. Coxon AT, et al. Among authors: leuthardt ec. J Cereb Blood Flow Metab. 2023 Aug;43(8):1382-1389. doi: 10.1177/0271678X231160891. Epub 2023 Mar 30. J Cereb Blood Flow Metab. 2023. PMID: 36994857 Free PMC article.
Radiation therapy dose escalation for glioblastoma multiforme in the era of temozolomide.
Badiyan SN, Markovina S, Simpson JR, Robinson CG, DeWees T, Tran DD, Linette G, Jalalizadeh R, Dacey R, Rich KM, Chicoine MR, Dowling JL, Leuthardt EC, Zipfel GJ, Kim AH, Huang J. Badiyan SN, et al. Among authors: leuthardt ec. Int J Radiat Oncol Biol Phys. 2014 Nov 15;90(4):877-85. doi: 10.1016/j.ijrobp.2014.07.014. Epub 2014 Sep 23. Int J Radiat Oncol Biol Phys. 2014. PMID: 25257812
A Multi-Institutional Analysis of Factors Influencing Surgical Outcomes for Patients with Newly Diagnosed Grade I Gliomas.
Yahanda AT, Patel B, Sutherland G, Honeycutt J, Jensen RL, Smyth MD, Limbrick DD Jr, Dacey RG Jr, Dowling JL, Dunn GP, Kim AH, Leuthardt EC, Rich KM, Zipfel GJ, Leonard JR, Cahill DP, Shah MV, Abram SR, Evans J, Tao Y, Chicoine MR. Yahanda AT, et al. Among authors: leuthardt ec. World Neurosurg. 2020 Mar;135:e754-e764. doi: 10.1016/j.wneu.2019.12.156. Epub 2019 Dec 31. World Neurosurg. 2020. PMID: 31901497
Impact of Intraoperative Magnetic Resonance Imaging and Other Factors on Surgical Outcomes for Newly Diagnosed Grade II Astrocytomas and Oligodendrogliomas: A Multicenter Study.
Yahanda AT, Patel B, Shah AS, Cahill DP, Sutherland G, Honeycutt J, Jensen RL, Rich KM, Dowling JL, Limbrick DD, Dacey RG, Kim AH, Leuthardt EC, Dunn GP, Zipfel GJ, Leonard JR, Smyth MD, Shah MV, Abram SR, Evans J, Chicoine MR. Yahanda AT, et al. Among authors: leuthardt ec. Neurosurgery. 2020 Dec 15;88(1):63-73. doi: 10.1093/neuros/nyaa320. Neurosurgery. 2020. PMID: 32717067
207 results