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Page 1
Novel Polygenic Risk Score and Established Clinical Risk Factors for Risk Estimation of Aortic Stenosis.
Small AM, Melloni GEM, Kamanu FK, Bergmark BA, Bonaca MP, O'Donoghue ML, Giugliano RP, Scirica BM, Bhatt D, Antman EM, Raz I, Wiviott SD, Truong B, Wilson PWF, Cho K, O'Donnell CJ, Braunwald E, Lubitz SA, Ellinor P, Peloso GM, Ruff CT, Sabatine MS, Natarajan P, Marston NA. Small AM, et al. Among authors: peloso gm. JAMA Cardiol. 2024 Apr 1;9(4):357-366. doi: 10.1001/jamacardio.2024.0011. JAMA Cardiol. 2024. PMID: 38416462 Clinical Trial.
Common variants at 30 loci contribute to polygenic dyslipidemia.
Kathiresan S, Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y, Tanaka T, Voight BF, Bonnycastle LL, Jackson AU, Crawford G, Surti A, Guiducci C, Burtt NP, Parish S, Clarke R, Zelenika D, Kubalanza KA, Morken MA, Scott LJ, Stringham HM, Galan P, Swift AJ, Kuusisto J, Bergman RN, Sundvall J, Laakso M, Ferrucci L, Scheet P, Sanna S, Uda M, Yang Q, Lunetta KL, Dupuis J, de Bakker PI, O'Donnell CJ, Chambers JC, Kooner JS, Hercberg S, Meneton P, Lakatta EG, Scuteri A, Schlessinger D, Tuomilehto J, Collins FS, Groop L, Altshuler D, Collins R, Lathrop GM, Melander O, Salomaa V, Peltonen L, Orho-Melander M, Ordovas JM, Boehnke M, Abecasis GR, Mohlke KL, Cupples LA. Kathiresan S, et al. Among authors: peloso gm. Nat Genet. 2009 Jan;41(1):56-65. doi: 10.1038/ng.291. Epub 2008 Dec 7. Nat Genet. 2009. PMID: 19060906 Free PMC article.
The early repolarization pattern in the general population: clinical correlates and heritability.
Noseworthy PA, Tikkanen JT, Porthan K, Oikarinen L, Pietilä A, Harald K, Peloso GM, Merchant FM, Jula A, Väänänen H, Hwang SJ, O'Donnell CJ, Salomaa V, Newton-Cheh C, Huikuri HV. Noseworthy PA, et al. Among authors: peloso gm. J Am Coll Cardiol. 2011 May 31;57(22):2284-9. doi: 10.1016/j.jacc.2011.04.003. J Am Coll Cardiol. 2011. PMID: 21600720 Free PMC article.
A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study.
Thanassoulis G, Peloso GM, Pencina MJ, Hoffmann U, Fox CS, Cupples LA, Levy D, D'Agostino RB, Hwang SJ, O'Donnell CJ. Thanassoulis G, et al. Among authors: peloso gm. Circ Cardiovasc Genet. 2012 Feb 1;5(1):113-21. doi: 10.1161/CIRCGENETICS.111.961342. Epub 2012 Jan 10. Circ Cardiovasc Genet. 2012. PMID: 22235037 Free PMC article.
A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern.
Sinner MF, Porthan K, Noseworthy PA, Havulinna AS, Tikkanen JT, Müller-Nurasyid M, Peloso G, Ulivi S, Beckmann BM, Brockhaus AC, Cooper RR, Gasparini P, Hengstenberg C, Hwang SJ, Iorio A, Junttila MJ, Klopp N, Kähönen M, Laaksonen MA, Lehtimäki T, Lichtner P, Lyytikäinen LP, Martens E, Meisinger C, Meitinger T, Merchant FM, Nieminen MS, Peters A, Pietilä A, Perz S, Oikarinen L, Raitakari O, Reinhard W, Silander K, Thorand B, Wichmann HE, Sinagra G, Viikari J, O'Donnell CJ, Ellinor PT, Huikuri HV, Kääb S, Newton-Cheh C, Salomaa V. Sinner MF, et al. Heart Rhythm. 2012 Oct;9(10):1627-34. doi: 10.1016/j.hrthm.2012.06.008. Epub 2012 Jun 6. Heart Rhythm. 2012. PMID: 22683750 Free PMC article.
QT interval and long-term mortality risk in the Framingham Heart Study.
Noseworthy PA, Peloso GM, Hwang SJ, Larson MG, Levy D, O'Donnell CJ, Newton-Cheh C. Noseworthy PA, et al. Among authors: peloso gm. Ann Noninvasive Electrocardiol. 2012 Oct;17(4):340-8. doi: 10.1111/j.1542-474X.2012.00535.x. Epub 2012 Aug 13. Ann Noninvasive Electrocardiol. 2012. PMID: 23094880 Free PMC article.
Resequencing and clinical associations of the 9p21.3 region: a comprehensive investigation in the Framingham heart study.
Johnson AD, Hwang SJ, Voorman A, Morrison A, Peloso GM, Hsu YH, Thanassoulis G, Newton-Cheh C, Rogers IS, Hoffmann U, Freedman JE, Fox CS, Psaty BM, Boerwinkle E, Cupples LA, O'Donnell CJ. Johnson AD, et al. Among authors: peloso gm. Circulation. 2013 Feb 19;127(7):799-810. doi: 10.1161/CIRCULATIONAHA.112.111559. Epub 2013 Jan 11. Circulation. 2013. PMID: 23315372 Free PMC article.
Association of low-density lipoprotein cholesterol-related genetic variants with aortic valve calcium and incident aortic stenosis.
Smith JG, Luk K, Schulz CA, Engert JC, Do R, Hindy G, Rukh G, Dufresne L, Almgren P, Owens DS, Harris TB, Peloso GM, Kerr KF, Wong Q, Smith AV, Budoff MJ, Rotter JI, Cupples LA, Rich S, Kathiresan S, Orho-Melander M, Gudnason V, O'Donnell CJ, Post WS, Thanassoulis G; Cohorts for Heart and Aging Research in Genetic Epidemiology (CHARGE) Extracoronary Calcium Working Group. Smith JG, et al. Among authors: peloso gm. JAMA. 2014 Nov 5;312(17):1764-71. doi: 10.1001/jama.2014.13959. JAMA. 2014. PMID: 25344734 Free PMC article.
194 results