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Touch sensation requires the mechanically gated ion channel ELKIN1.
Chakrabarti S, Klich JD, Khallaf MA, Hulme AJ, Sánchez-Carranza O, Baran ZM, Rossi A, Huang AT, Pohl T, Fleischer R, Fürst C, Hammes A, Bégay V, Hörnberg H, Finol-Urdaneta RK, Poole K, Dottori M, Lewin GR. Chakrabarti S, et al. Among authors: fleischer r. Science. 2024 Mar;383(6686):992-998. doi: 10.1126/science.adl0495. Epub 2024 Feb 29. Science. 2024. PMID: 38422143
TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration.
Patkunarajah A, Stear JH, Moroni M, Schroeter L, Blaszkiewicz J, Tearle JL, Cox CD, Fürst C, Sánchez-Carranza O, Ocaña Fernández MDÁ, Fleischer R, Eravci M, Weise C, Martinac B, Biro M, Lewin GR, Poole K. Patkunarajah A, et al. Among authors: fleischer r. Elife. 2020 Apr 1;9:e53308. doi: 10.7554/eLife.53308. Elife. 2020. PMID: 32228863 Free PMC article.
Voltage gating of mechanosensitive PIEZO channels.
Moroni M, Servin-Vences MR, Fleischer R, Sánchez-Carranza O, Lewin GR. Moroni M, et al. Among authors: fleischer r. Nat Commun. 2018 Mar 15;9(1):1096. doi: 10.1038/s41467-018-03502-7. Nat Commun. 2018. PMID: 29545531 Free PMC article.
Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity.
Wetzel C, Pifferi S, Picci C, Gök C, Hoffmann D, Bali KK, Lampe A, Lapatsina L, Fleischer R, Smith ES, Bégay V, Moroni M, Estebanez L, Kühnemund J, Walcher J, Specker E, Neuenschwander M, von Kries JP, Haucke V, Kuner R, Poulet JF, Schmoranzer J, Poole K, Lewin GR. Wetzel C, et al. Among authors: fleischer r. Nat Neurosci. 2017 Feb;20(2):209-218. doi: 10.1038/nn.4454. Epub 2016 Dec 12. Nat Neurosci. 2017. PMID: 27941788 Free article.
Sequence capture identifies fastidious chytrid fungi directly from host tissue.
Mulder KP, Savage AE, Gratwicke B, Longcore JE, Bronikowski E, Evans M, Longo AV, Kurata NP, Walsh T, Pasmans F, McInerney N, Murray S, Martel A, Fleischer RC. Mulder KP, et al. Among authors: fleischer rc. Fungal Genet Biol. 2024 Feb;170:103858. doi: 10.1016/j.fgb.2023.103858. Epub 2023 Dec 13. Fungal Genet Biol. 2024. PMID: 38101696
280 results