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Touch sensation requires the mechanically gated ion channel ELKIN1.
Chakrabarti S, Klich JD, Khallaf MA, Hulme AJ, Sánchez-Carranza O, Baran ZM, Rossi A, Huang AT, Pohl T, Fleischer R, Fürst C, Hammes A, Bégay V, Hörnberg H, Finol-Urdaneta RK, Poole K, Dottori M, Lewin GR. Chakrabarti S, et al. Among authors: poole k. Science. 2024 Mar;383(6686):992-998. doi: 10.1126/science.adl0495. Epub 2024 Feb 29. Science. 2024. PMID: 38422143
TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration.
Patkunarajah A, Stear JH, Moroni M, Schroeter L, Blaszkiewicz J, Tearle JL, Cox CD, Fürst C, Sánchez-Carranza O, Ocaña Fernández MDÁ, Fleischer R, Eravci M, Weise C, Martinac B, Biro M, Lewin GR, Poole K. Patkunarajah A, et al. Among authors: poole k. Elife. 2020 Apr 1;9:e53308. doi: 10.7554/eLife.53308. Elife. 2020. PMID: 32228863 Free PMC article.
Mechanoelectrical transduction in chondrocytes.
Servin-Vences MR, Richardson J, Lewin GR, Poole K. Servin-Vences MR, et al. Among authors: poole k. Clin Exp Pharmacol Physiol. 2018 May;45(5):481-488. doi: 10.1111/1440-1681.12917. Epub 2018 Feb 19. Clin Exp Pharmacol Physiol. 2018. PMID: 29359488 Review.
Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity.
Wetzel C, Pifferi S, Picci C, Gök C, Hoffmann D, Bali KK, Lampe A, Lapatsina L, Fleischer R, Smith ES, Bégay V, Moroni M, Estebanez L, Kühnemund J, Walcher J, Specker E, Neuenschwander M, von Kries JP, Haucke V, Kuner R, Poulet JF, Schmoranzer J, Poole K, Lewin GR. Wetzel C, et al. Among authors: poole k. Nat Neurosci. 2017 Feb;20(2):209-218. doi: 10.1038/nn.4454. Epub 2016 Dec 12. Nat Neurosci. 2017. PMID: 27941788 Free article.
Stomatin-domain proteins.
Lapatsina L, Brand J, Poole K, Daumke O, Lewin GR. Lapatsina L, et al. Among authors: poole k. Eur J Cell Biol. 2012 Apr;91(4):240-5. doi: 10.1016/j.ejcb.2011.01.018. Epub 2011 Apr 17. Eur J Cell Biol. 2012. PMID: 21501885 Review.
515 results