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Ebola virus VP35 interacts non-covalently with ubiquitin chains to promote viral replication.
Rodríguez-Salazar CA, van Tol S, Mailhot O, Gonzalez-Orozco M, Galdino GT, Warren AN, Teruel N, Behera P, Afreen KS, Zhang L, Juelich TL, Smith JK, Zylber MI, Freiberg AN, Najmanovich RJ, Giraldo MI, Rajsbaum R. Rodríguez-Salazar CA, et al. Among authors: freiberg an. PLoS Biol. 2024 Feb 29;22(2):e3002544. doi: 10.1371/journal.pbio.3002544. eCollection 2024 Feb. PLoS Biol. 2024. PMID: 38422166 Free PMC article.
Ebola Virus VP35 Interacts Non-Covalently with Ubiquitin Chains to Promote Viral Replication Creating New Therapeutic Opportunities.
Rodríguez-Salazar CA, van Tol S, Mailhot O, Galdino G, Teruel N, Zhang L, Warren AN, González-Orozco M, Freiberg AN, Najmanovich RJ, Giraldo MI, Rajsbaum R. Rodríguez-Salazar CA, et al. Among authors: freiberg an. bioRxiv [Preprint]. 2023 Jul 15:2023.07.14.549057. doi: 10.1101/2023.07.14.549057. bioRxiv. 2023. PMID: 37503276 Free PMC article. Updated. Preprint.
Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly.
van Tol S, Kalveram B, Ilinykh PA, Ronk A, Huang K, Aguilera-Aguirre L, Bharaj P, Hage A, Atkins C, Giraldo MI, Wakamiya M, Gonzalez-Orozco M, Warren AN, Bukreyev A, Freiberg AN, Rajsbaum R. van Tol S, et al. Among authors: freiberg an. PLoS Pathog. 2022 May 9;18(5):e1010532. doi: 10.1371/journal.ppat.1010532. eCollection 2022 May. PLoS Pathog. 2022. PMID: 35533195 Free PMC article.
The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity.
Hage A, Bharaj P, van Tol S, Giraldo MI, Gonzalez-Orozco M, Valerdi KM, Warren AN, Aguilera-Aguirre L, Xie X, Widen SG, Moulton HM, Lee B, Johnson JR, Krogan NJ, García-Sastre A, Shi PY, Freiberg AN, Rajsbaum R. Hage A, et al. Among authors: freiberg an. Cell Rep. 2022 Mar 8;38(10):110434. doi: 10.1016/j.celrep.2022.110434. Cell Rep. 2022. PMID: 35263596 Free PMC article.
112 results