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Biomarker-based staging of Alzheimer disease: rationale and clinical applications.
Therriault J, Schindler SE, Salvadó G, Pascoal TA, Benedet AL, Ashton NJ, Karikari TK, Apostolova L, Murray ME, Verberk I, Vogel JW, La Joie R, Gauthier S, Teunissen C, Rabinovici GD, Zetterberg H, Bateman RJ, Scheltens P, Blennow K, Sperling R, Hansson O, Jack CR Jr, Rosa-Neto P. Therriault J, et al. Among authors: ashton nj. Nat Rev Neurol. 2024 Apr;20(4):232-244. doi: 10.1038/s41582-024-00942-2. Epub 2024 Mar 1. Nat Rev Neurol. 2024. PMID: 38429551 Review.
Blood metabolite markers of neocortical amyloid-β burden: discovery and enrichment using candidate proteins.
Voyle N, Kim M, Proitsi P, Ashton NJ, Baird AL, Bazenet C, Hye A, Westwood S, Chung R, Ward M, Rabinovici GD, Lovestone S, Breen G, Legido-Quigley C, Dobson RJ, Kiddle SJ; Alzheimer's Disease Neuroimaging Initiative. Voyle N, et al. Among authors: ashton nj. Transl Psychiatry. 2016 Jan 26;6(1):e719. doi: 10.1038/tp.2015.205. Transl Psychiatry. 2016. PMID: 26812040 Free PMC article.
Blood protein predictors of brain amyloid for enrichment in clinical trials?
Ashton NJ, Kiddle SJ, Graf J, Ward M, Baird AL, Hye A, Westwood S, Wong KV, Dobson RJ, Rabinovici GD, Miller BL, Rosen HJ, Torres A, Zhang Z, Thurfjell L, Covin A, Hehir CT, Baker D, Bazenet C, Lovestone S; AIBL Research Group. Ashton NJ, et al. Alzheimers Dement (Amst). 2015 Mar 29;1(1):48-60. doi: 10.1016/j.dadm.2014.11.005. eCollection 2015 Mar. Alzheimers Dement (Amst). 2015. PMID: 27239491 Free PMC article.
Update on biomarkers for amyloid pathology in Alzheimer's disease.
Ashton NJ, Schöll M, Heurling K, Gkanatsiou E, Portelius E, Höglund K, Brinkmalm G, Hye A, Blennow K, Zetterberg H. Ashton NJ, et al. Biomark Med. 2018 Jul;12(7):799-812. doi: 10.2217/bmm-2017-0433. Epub 2018 Jun 15. Biomark Med. 2018. PMID: 29902934 Review.
Biomarkers for tau pathology.
Schöll M, Maass A, Mattsson N, Ashton NJ, Blennow K, Zetterberg H, Jagust W. Schöll M, et al. Among authors: ashton nj. Mol Cell Neurosci. 2019 Jun;97:18-33. doi: 10.1016/j.mcn.2018.12.001. Epub 2018 Dec 7. Mol Cell Neurosci. 2019. PMID: 30529601 Free PMC article. Review.
Plasma Protein Biomarkers for the Prediction of CSF Amyloid and Tau and [18F]-Flutemetamol PET Scan Result.
Westwood S, Baird AL, Hye A, Ashton NJ, Nevado-Holgado AJ, Anand SN, Liu B, Newby D, Bazenet C, Kiddle SJ, Ward M, Newton B, Desai K, Tan Hehir C, Zanette M, Galimberti D, Parnetti L, Lleó A, Baker S, Narayan VA, van der Flier WM, Scheltens P, Teunissen CE, Visser PJ, Lovestone S. Westwood S, et al. Among authors: ashton nj. Front Aging Neurosci. 2018 Dec 11;10:409. doi: 10.3389/fnagi.2018.00409. eCollection 2018. Front Aging Neurosci. 2018. PMID: 30618716 Free PMC article.
A plasma protein classifier for predicting amyloid burden for preclinical Alzheimer's disease.
Ashton NJ, Nevado-Holgado AJ, Barber IS, Lynham S, Gupta V, Chatterjee P, Goozee K, Hone E, Pedrini S, Blennow K, Schöll M, Zetterberg H, Ellis KA, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Aarsland D, Powell J, Lovestone S, Martins R, Hye A. Ashton NJ, et al. Sci Adv. 2019 Feb 6;5(2):eaau7220. doi: 10.1126/sciadv.aau7220. eCollection 2019 Feb. Sci Adv. 2019. PMID: 30775436 Free PMC article.
Synaptic vesicle protein 2A as a potential biomarker in synaptopathies.
Heurling K, Ashton NJ, Leuzy A, Zimmer ER, Blennow K, Zetterberg H, Eriksson J, Lubberink M, Schöll M. Heurling K, et al. Among authors: ashton nj. Mol Cell Neurosci. 2019 Jun;97:34-42. doi: 10.1016/j.mcn.2019.02.001. Epub 2019 Feb 20. Mol Cell Neurosci. 2019. PMID: 30796959 Free article. Review.
249 results