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Biomarker-based staging of Alzheimer disease: rationale and clinical applications.
Therriault J, Schindler SE, Salvadó G, Pascoal TA, Benedet AL, Ashton NJ, Karikari TK, Apostolova L, Murray ME, Verberk I, Vogel JW, La Joie R, Gauthier S, Teunissen C, Rabinovici GD, Zetterberg H, Bateman RJ, Scheltens P, Blennow K, Sperling R, Hansson O, Jack CR Jr, Rosa-Neto P. Therriault J, et al. Among authors: gauthier s. Nat Rev Neurol. 2024 Apr;20(4):232-244. doi: 10.1038/s41582-024-00942-2. Epub 2024 Mar 1. Nat Rev Neurol. 2024. PMID: 38429551 Review.
Astrocyte reactivity influences the association of amyloid-β and tau biomarkers in preclinical Alzheimer's disease.
Pascoal T, Bellaver B, Povala G, Ferreira P, Ferrari-Souza JP, Leffa D, Lussier F, Benedet A, Ashton N, Triana-Baltzerz G, Kolbzh H, Tissot C, Therriault J, Servaes S, Stevenson J, Rahmouni N, Lopez O, Tudorascu D, Villemagne V, Ikonomovic M, Gauthier S, Zimmer E, Zetterberg H, Blennow K, Aizenstein H, Klunk W, Snitz B, Maki P, Thurston R, Cohen A, Ganguli M, Karikari T, Rosa-Neto P. Pascoal T, et al. Among authors: gauthier s. Res Sq [Preprint]. 2023 Feb 1:rs.3.rs-2507179. doi: 10.21203/rs.3.rs-2507179/v1. Res Sq. 2023. PMID: 36778243 Free PMC article. Updated. Preprint.
Comparison of immunoassay- with mass spectrometry-derived p-tau quantification for the detection of Alzheimer's disease pathology.
Therriault J, Woo MS, Salvadó G, Gobom J, Karikari TK, Janelidze S, Servaes S, Rahmouni N, Tissot C, Ashton NJ, Benedet AL, Montoliu-Gaya L, Macedo AC, Lussier FZ, Stevenson J, Vitali P, Friese MA, Massarweh G, Soucy JP, Pascoal TA, Stomrud E, Palmqvist S, Mattsson-Carlgren N, Gauthier S, Zetterberg H, Hansson O, Blennow K, Rosa-Neto P. Therriault J, et al. Among authors: gauthier s. Mol Neurodegener. 2024 Jan 7;19(1):2. doi: 10.1186/s13024-023-00689-2. Mol Neurodegener. 2024. PMID: 38185677 Free PMC article.
NfL reliability across laboratories, stage-dependent diagnostic performance and matrix comparability in genetic FTD: a large GENFI study.
Linnemann C, Wilke C, Mengel D, Zetterberg H, Heller C, Kuhle J, Bouzigues A, Russell LL, Foster PH, Ferry-Bolder E, Van Swieten JC, Jiskoot LC, Seelaar H, Moreno F, Borroni B, Sánchez-Valle R, Galimberti D, Laforce R Jr, Graff C, Masellis M, Tartaglia MC, Rowe JB, Finger E, Vandenberghe R, de Mendonca A, Butler CR, Gerhard A, Ducharme S, Ber ILE, Tiraboschi P, Santana I, Pasquier F, Levin J, Otto M, Sorbi S, Rohrer JD, Synofzik M; GENFI. Linnemann C, et al. J Neurol Neurosurg Psychiatry. 2024 Feb 1:jnnp-2023-332464. doi: 10.1136/jnnp-2023-332464. Online ahead of print. J Neurol Neurosurg Psychiatry. 2024. PMID: 38253362 Free article.
Clinical Correlates of the PET-based Braak Staging Framework in Alzheimer's Disease.
Macedo AC, Durço DFPA, Tissot C, Therriault J, Vilela de Faria AO, Aumont É, Servaes S, Rahmouni N, Fernandez-Arias J, Wang YT, Lussier FZ, Bieger A, Zimmer ER, Pascoal TA, Gauthier S, Rosa-Neto P. Macedo AC, et al. Among authors: gauthier s. J Prev Alzheimers Dis. 2024;11(2):414-421. doi: 10.14283/jpad.2024.15. J Prev Alzheimers Dis. 2024. PMID: 38374747 Review.
Predicting functional decline in aging and Alzheimer's disease with PET-based Braak staging.
Macedo AC, Therriault J, Tissot C, Fernandez-Arias J, Ferreira PCL, Vitali P, Servaes S, Rahmouni N, Vermeiren M, Bezgin G, Lussier FZ, Stevenson J, Wang YT, Socualaya KQ, Kunach P, Nazneen T, Hosseini SA, Pallen V, Stevenson A, Ferrari-Souza JP, Bellaver B, Leffa DT, Ng KP, Zimmer ER, Pascoal TA, Gauthier S, Rosa-Neto P. Macedo AC, et al. Among authors: gauthier s. Brain Commun. 2024 Feb 26;6(2):fcae043. doi: 10.1093/braincomms/fcae043. eCollection 2024. Brain Commun. 2024. PMID: 38482373 Free PMC article.
Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial.
Wagemann O, Liu H, Wang G, Shi X, Bittner T, Scelsi MA, Farlow MR, Clifford DB, Supnet-Bell C, Santacruz AM, Aschenbrenner AJ, Hassenstab JJ, Benzinger TLS, Gordon BA, Coalier KA, Cruchaga C, Ibanez L, Perrin RJ, Xiong C, Li Y, Morris JC, Lah JJ, Berman SB, Roberson ED, van Dyck CH, Galasko D, Gauthier S, Hsiung GR, Brooks WS, Pariente J, Mummery CJ, Day GS, Ringman JM, Mendez PC, St George-Hyslop P, Fox NC, Suzuki K, Okhravi HR, Chhatwal J, Levin J, Jucker M, Sims JR, Holdridge KC, Proctor NK, Yaari R, Andersen SW, Mancini M, Llibre-Guerra J, Bateman RJ, McDade E; Dominantly Inherited Alzheimer Network–Trials Unit. Wagemann O, et al. Among authors: gauthier s. JAMA Neurol. 2024 Apr 29:e240991. doi: 10.1001/jamaneurol.2024.0991. Online ahead of print. JAMA Neurol. 2024. PMID: 38683602 Free PMC article.
The relation of synaptic biomarkers with Aβ, tau, glial activation, and neurodegeneration in Alzheimer's disease.
Wang YT, Ashton NJ, Servaes S, Nilsson J, Woo MS, Pascoal TA, Tissot C, Rahmouni N, Therriault J, Lussier F, Chamoun M, Gauthier S, Brinkmalm A, Zetterberg H, Blennow K, Rosa-Neto P, Benedet AL. Wang YT, et al. Among authors: gauthier s. Transl Neurodegener. 2024 May 28;13(1):27. doi: 10.1186/s40035-024-00420-1. Transl Neurodegener. 2024. PMID: 38802928 Free PMC article. No abstract available.
Education modulates brain maintenance in presymptomatic frontotemporal dementia.
Gazzina S, Grassi M, Premi E, Cosseddu M, Alberici A, Archetti S, Gasparotti R, Van Swieten J, Galimberti D, Sanchez-Valle R, Laforce RJ, Moreno F, Synofzik M, Graff C, Masellis M, Tartaglia MC, Rowe JB, Vandenberghe R, Finger E, Tagliavini F, de Mendonça A, Santana I, Butler CR, Ducharme S, Gerhard A, Danek A, Levin J, Otto M, Frisoni G, Sorbi S, Padovani A, Rohrer JD, Borroni B; Genetic FTD Initiative, GENFI. Gazzina S, et al. J Neurol Neurosurg Psychiatry. 2019 Oct;90(10):1124-1130. doi: 10.1136/jnnp-2019-320439. Epub 2019 Jun 10. J Neurol Neurosurg Psychiatry. 2019. PMID: 31182509
1,104 results