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Natural history of adults with KBG syndrome: a physician-reported experience.
Bayat A, Grimes H, de Boer E, Herlin MK, Dahl RS, Lund ICB, Bayat M, Skjelmose Bolund AC, Gjerulfsen CE, Gregersen PA, Zilmer M, Juhl S, Cebula K, Rahikkala E, Maystadt I, Peron A, Vignoli A, Alfano RM, Stanzial F, Benedicenti F, Currò A, Luk HM, Jouret G, Zurita E, Heuft L, Schnabel F, Busche A, Veenstra-Knol HE, Tkemaladze T, Vrielynck P, Lederer D, Platzer K, Ockeloen CW, Goel H, Low KJ. Bayat A, et al. Genet Med. 2024 May 27:101170. doi: 10.1016/j.gim.2024.101170. Online ahead of print. Genet Med. 2024. PMID: 38818797
RESULTS: The international collaboration identified 36 adults from 31 unrelated families with KBGS. Symptopms included mild/borderline intellectual disability (n=22); gross and/or fine motor difficulties (n=15); psychiatric and behavioral comorbidities including agg …
RESULTS: The international collaboration identified 36 adults from 31 unrelated families with KBGS. Symptopms included mild/borderline intel …
Evaluation of an E6/E7 PCR-capillary electrophoresis fragment analysis in the genotyping of human papillomavirus in archival FFPE samples of oropharyngeal cancer.
Yin J, Li Y, Song C, Liu Y, Zhao J, Zhao D, Zhang S, Zhang X, Zhao F, Qiao Y. Yin J, et al. J Med Virol. 2024 Jun;96(6):e29716. doi: 10.1002/jmv.29716. J Med Virol. 2024. PMID: 38818787
The level of agreement of two assays was determined using Cohen's Kappa (kappa) statistics. A total of 230 FFPE OPSCC samples from tumor resections (n = 160) and diagnostic biopsies (n = 70) were detected. Sixty-six (28.7%) and 70 (30.4%) samples were identified as …
The level of agreement of two assays was determined using Cohen's Kappa (kappa) statistics. A total of 230 FFPE OPSCC samples from tumor res …
Depressive symptoms in adolescence and adult educational and employment outcomes: a structured life course analysis.
López-López JA, Tilling K, Pearson RM, Fazel MS, Washbrook E, Zhu Y, Smith BJ, Dunn EC, Smith ADAC. López-López JA, et al. Psychol Med. 2024 May 31:1-8. doi: 10.1017/S0033291724001090. Online ahead of print. Psychol Med. 2024. PMID: 38818779
RESULTS: Our analysis sample included participants with full information on NEET status (N = 3951), and the results supported the accumulation of risk model, showing that the odds of NEET increase by 1.015 (95% CI 1.012-1.019) for an increase of 1 unit in depression at any …
RESULTS: Our analysis sample included participants with full information on NEET status (N = 3951), and the results supported the acc …
Tobacco exposures are associated with health care utilization (HCU) and health care costs in pregnant persons and their newborn babies.
Fuemmeler BF, Dahman B, Glasgow TE, Barsell DJ, Oliver JA, Zhang J, Hoyo C, Murphy SK, McClernon FJ, Wheeler DC. Fuemmeler BF, et al. Nicotine Tob Res. 2024 May 31:ntae128. doi: 10.1093/ntr/ntae128. Online ahead of print. Nicotine Tob Res. 2024. PMID: 38818778
Participants included those for whom prenatal serum samples were assayed and for whom administrative data were obtainable (N=1,045). Zero-inflated Poisson (ZIP) regression models were used to assess associations between cotinine, adjusted for covariates (e.g., race and eth …
Participants included those for whom prenatal serum samples were assayed and for whom administrative data were obtainable (N=1,045). …
Vesicle-vesicle fusion promoted by the Atg8-family autophagy protein LC3C: relevance of the N-terminal region.
Ballesteros U, Alonso A, Montes LR, Etxaniz A. Ballesteros U, et al. Autophagy. 2024 May 31:1-3. doi: 10.1080/15548627.2024.2359354. Online ahead of print. Autophagy. 2024. PMID: 38818767
Our own research data demonstrate that LC3C induces higher levels of tethering and of intervesicular lipid mixing than LC3B. LC3C contains a peculiar N-terminal region, different from the other Atg8-family protein members. Using a series of mutants, we have shown that the …
Our own research data demonstrate that LC3C induces higher levels of tethering and of intervesicular lipid mixing than LC3B. LC3C contains a …
An opt-out tobacco treatment group intervention within an intensive substance use disorders treatment program: Initial outcomes in the Veterans Health Administration.
Bertucci S, Schultz E, Stevenson B, Fu SS. Bertucci S, et al. Nicotine Tob Res. 2024 May 31:ntae134. doi: 10.1093/ntr/ntae134. Online ahead of print. Nicotine Tob Res. 2024. PMID: 38818765
Patient self-report and medical chart review were utilized to identify individuals who began a tobacco cessation medication during treatment as well as those who reported quitting tobacco, defined as sustained tobacco abstinence for at least seven days. The analysis includes a to …
Patient self-report and medical chart review were utilized to identify individuals who began a tobacco cessation medication during treatment …
Manipulation of the Myc Interactome to Enhance Nerve Regeneration in a Murine Model.
Poitras TM, Komirishetty P, Areti A, Larouche M, Krishnan A, Chandrasekhar A, Munchrath E, Zochodne DW. Poitras TM, et al. Ann Neurol. 2024 May 31. doi: 10.1002/ana.26950. Online ahead of print. Ann Neurol. 2024. PMID: 38818756
METHODS: Expression and impact of Myc interactome members c-Myc, N-Myc, Mad1, and Max were evaluated within naive and "preconditioned" adult sensory neurons and Schwann cells (SCs), using siRNA and transfection of CRISPR/Cas9 or luciferase reporter in vitro. Morphological, …
METHODS: Expression and impact of Myc interactome members c-Myc, N-Myc, Mad1, and Max were evaluated within naive and "preconditioned …
Effect of the Blood Pressure and Antihypertensive Drugs on Cerebral Small Vessel Disease: A Mendelian Randomization Study.
Ma Y, Wang M, Chen X, Yao J, Ding Y, Gao Q, Zhou J, Lian X. Ma Y, et al. Stroke. 2024 May 31. doi: 10.1161/STROKEAHA.123.045664. Online ahead of print. Stroke. 2024. PMID: 38818733
METHODS: We extracted single-nucleotide polymorphisms for systolic BP and diastolic BP from a genome-wide association study (N=757 601) and screened single-nucleotide polymorphisms associated with calcium channel blockers, thiazides, angiotensin-converting enzyme inhibitor …
METHODS: We extracted single-nucleotide polymorphisms for systolic BP and diastolic BP from a genome-wide association study (N=757 60 …
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