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Page 1
Excess of body weight is associated with accelerated T-cell senescence in hospitalized COVID-19 patients.
Madruga MP, Grun LK, Santos LSMD, Friedrich FO, Antunes DB, Rocha MEF, Silva PL, Dorneles GP, Teixeira PC, Oliveira TF, Romão PRT, Santos L, Moreira JCF, Michaelsen VS, Cypel M, Antunes MOB, Jones MH, Barbé-Tuana FM, Bauer ME. Madruga MP, et al. Among authors: michaelsen vs. Immun Ageing. 2024 Mar 8;21(1):17. doi: 10.1186/s12979-024-00423-6. Immun Ageing. 2024. PMID: 38454515 Free PMC article.
Successful 3-day lung preservation using a cyclic normothermic ex vivo lung perfusion strategy.
Ali A, Nykanen AI, Beroncal E, Brambate E, Mariscal A, Michaelsen V, Wang A, Kawashima M, Ribeiro RVP, Zhang Y, Fan E, Brochard L, Yeung J, Waddell T, Liu M, Andreazza AC, Keshavjee S, Cypel M. Ali A, et al. EBioMedicine. 2022 Sep;83:104210. doi: 10.1016/j.ebiom.2022.104210. Epub 2022 Aug 8. EBioMedicine. 2022. PMID: 35952495 Free PMC article.
Ex vivo treatment of cytomegalovirus in human donor lungs using a novel chemokine-based immunotoxin.
Ribeiro RVP, Ku T, Wang A, Pires L, Ferreira VH, Michaelsen V, Ali A, Galasso M, Moshkelgosha S, Gazzalle A, Jeppesen MG, Rosenkilde MM, Liu M, Singer LG, Kumar D, Keshavjee S, Sinclair J, Kledal TN, Humar A, Cypel M. Ribeiro RVP, et al. J Heart Lung Transplant. 2022 Mar;41(3):287-297. doi: 10.1016/j.healun.2021.10.010. Epub 2021 Oct 25. J Heart Lung Transplant. 2022. PMID: 34802874
Static lung storage at 10°C maintains mitochondrial health and preserves donor organ function.
Ali A, Wang A, Ribeiro RVP, Beroncal EL, Baciu C, Galasso M, Gomes B, Mariscal A, Hough O, Brambate E, Abdelnour-Berchtold E, Michaelsen V, Zhang Y, Gazzalle A, Fan E, Brochard L, Yeung J, Waddell T, Liu M, Andreazza AC, Keshavjee S, Cypel M. Ali A, et al. Sci Transl Med. 2021 Sep 15;13(611):eabf7601. doi: 10.1126/scitranslmed.abf7601. Epub 2021 Sep 15. Sci Transl Med. 2021. PMID: 34524862
Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs.
Wang A, Ribeiro RVP, Ali A, Brambate E, Abdelnour-Berchtold E, Michaelsen V, Zhang Y, Rahfeld P, Moon H, Gokhale H, Gazzalle A, Pal P, Liu M, Waddell TK, Cserti-Gazdewich C, Tinckam K, Kizhakkedathu JN, West L, Keshavjee S, Withers SG, Cypel M. Wang A, et al. Sci Transl Med. 2022 Feb 16;14(632):eabm7190. doi: 10.1126/scitranslmed.abm7190. Epub 2022 Feb 16. Sci Transl Med. 2022. PMID: 35171649