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Page 1
[Modeling T2 high severe asthma using human induced pluripotent stem cells (hiPSC)].
Ahmed E, Assou S, Foisset F, Bourdais C, Vanheerswynghels M, Petit A, Gamez AS, Gras D, Chanez P, de Vos J, Hammad H, Bourdin A, Lambrecht B. Ahmed E, et al. Among authors: vanheerswynghels m. Rev Mal Respir. 2024 Apr;41(4):289-293. doi: 10.1016/j.rmr.2024.02.012. Epub 2024 Mar 8. Rev Mal Respir. 2024. PMID: 38461089 French.
Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection.
Vetters J, van Helden M, De Nolf C, Rennen S, Cloots E, Van De Velde E, Fayazpour F, Van Moorleghem J, Vanheerswynghels M, Vergote K, Boon L, Vivier E, Lambrecht BN, Janssens S. Vetters J, et al. Among authors: vanheerswynghels m. iScience. 2023 Nov 23;26(12):108570. doi: 10.1016/j.isci.2023.108570. eCollection 2023 Dec 15. iScience. 2023. PMID: 38162021 Free PMC article.
STE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity.
Maes B, Fayazpour F, Catrysse L, Lornet G, Van De Velde E, De Wolf C, De Prijck S, Van Moorleghem J, Vanheerswynghels M, Deswarte K, Descamps B, Vanhove C, Van der Schueren B, Vangoitsenhoven R, Hammad H, Janssens S, Lambrecht BN. Maes B, et al. Among authors: vanheerswynghels m. J Exp Med. 2023 Sep 4;220(9):e20210788. doi: 10.1084/jem.20210788. Epub 2023 Jun 22. J Exp Med. 2023. PMID: 37347461 Free PMC article.
TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C.
Hoste L, Roels L, Naesens L, Bosteels V, Vanhee S, Dupont S, Bosteels C, Browaeys R, Vandamme N, Verstaen K, Roels J, Van Damme KFA, Maes B, De Leeuw E, Declercq J, Aegerter H, Seys L, Smole U, De Prijck S, Vanheerswynghels M, Claes K, Debacker V, Van Isterdael G, Backers L, Claes KBM, Bastard P, Jouanguy E, Zhang SY, Mets G, Dehoorne J, Vandekerckhove K, Schelstraete P, Willems J; MIS-C Clinicians; Stordeur P, Janssens S, Beyaert R, Saeys Y, Casanova JL, Lambrecht BN, Haerynck F, Tavernier SJ. Hoste L, et al. Among authors: vanheerswynghels m. J Exp Med. 2022 Feb 7;219(2):e20211381. doi: 10.1084/jem.20211381. Epub 2021 Dec 16. J Exp Med. 2022. PMID: 34914824 Free PMC article.
The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice.
Maes B, Smole U, Vanderkerken M, Deswarte K, Van Moorleghem J, Vergote K, Vanheerswynghels M, De Wolf C, De Prijck S, Debeuf N, Pavie B, Toussaint W, Janssens S, Savvides S, Lambrecht BN, Hammad H. Maes B, et al. Among authors: vanheerswynghels m. J Allergy Clin Immunol. 2022 Apr;149(4):1413-1427.e2. doi: 10.1016/j.jaci.2021.08.020. Epub 2021 Sep 8. J Allergy Clin Immunol. 2022. PMID: 34506849
CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Immunity by the Human Vaccine Adjuvant System AS01.
Bosteels C, Fierens K, De Prijck S, Van Moorleghem J, Vanheerswynghels M, De Wolf C, Chalon A, Collignon C, Hammad H, Didierlaurent AM, Lambrecht BN. Bosteels C, et al. Among authors: vanheerswynghels m. Front Immunol. 2021 Jan 14;11:606805. doi: 10.3389/fimmu.2020.606805. eCollection 2020. Front Immunol. 2021. PMID: 33519816 Free PMC article.
TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells.
Vanderkerken M, Maes B, Vandersarren L, Toussaint W, Deswarte K, Vanheerswynghels M, Pouliot P, Martens L, Van Gassen S, Arthur CM, Kirkling ME, Reizis B, Conrad D, Stowell S, Hammad H, Lambrecht BN. Vanderkerken M, et al. Among authors: vanheerswynghels m. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31331-31342. doi: 10.1073/pnas.2009847117. Epub 2020 Nov 19. Proc Natl Acad Sci U S A. 2020. PMID: 33214146 Free PMC article.
Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.
Bosteels C, Neyt K, Vanheerswynghels M, van Helden MJ, Sichien D, Debeuf N, De Prijck S, Bosteels V, Vandamme N, Martens L, Saeys Y, Louagie E, Lesage M, Williams DL, Tang SC, Mayer JU, Ronchese F, Scott CL, Hammad H, Guilliams M, Lambrecht BN. Bosteels C, et al. Among authors: vanheerswynghels m. Immunity. 2020 Jun 16;52(6):1039-1056.e9. doi: 10.1016/j.immuni.2020.04.005. Epub 2020 May 8. Immunity. 2020. PMID: 32392463 Free PMC article.
The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF.
Vetters J, van Helden MJ, Wahlen S, Tavernier SJ, Martens A, Fayazpour F, Vergote K, Vanheerswynghels M, Deswarte K, Van Moorleghem J, De Prijck S, Takahashi N, Vandenabeele P, Boon L, van Loo G, Vivier E, Lambrecht BN, Janssens S. Vetters J, et al. Among authors: vanheerswynghels m. J Exp Med. 2019 Sep 2;216(9):2010-2023. doi: 10.1084/jem.20182164. Epub 2019 Jul 11. J Exp Med. 2019. PMID: 31296735 Free PMC article.
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