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Page 1
Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy.
Panigrahy D, Kelly AG, Wang W, Yang J, Hwang SH, Gillespie M, Howard I, Bueno-Beti C, Asimaki A, Penna V, Lavine K, Edin ML, Zeldin DC, Hammock BD, Saffitz JE. Panigrahy D, et al. Among authors: hwang sh. bioRxiv [Preprint]. 2024 Feb 19:2024.02.17.580812. doi: 10.1101/2024.02.17.580812. bioRxiv. 2024. PMID: 38463975 Free PMC article. Preprint.
Hepatocyte-specific disruption of soluble epoxide hydrolase attenuates abdominal aortic aneurysm formation: novel role of the liver in aneurysm pathogenesis.
Kim D, Horimatsu T, Ogbi M, Goo B, Shi H, Veerapaneni P, Chouhaita R, Moses M, Prasad R, Benson TW, Harb R, Aboud G, Seller H, Haigh S, Fulton DJ, Csányi G, Huo Y, Long X, Coffey P, Lee R, Guha A, Zeldin D, Hwang SH, Hammock BD, Weintraub NL, Kim HW. Kim D, et al. Among authors: hwang sh. bioRxiv [Preprint]. 2023 Jul 11:2023.07.10.548127. doi: 10.1101/2023.07.10.548127. bioRxiv. 2023. PMID: 37503031 Free PMC article. Preprint.
Enhancing cancer immunotherapy via inhibition of soluble epoxide hydrolase.
Kelly AG, Wang W, Rothenberger E, Yang J, Gilligan MM, Kipper FC, Attaya A, Gartung A, Hwang SH, Gillespie MJ, Bayer RL, Quinlivan KM, Torres KL, Huang S, Mitsiades N, Yang H, Hammock BD, Panigrahy D. Kelly AG, et al. Among authors: hwang sh. Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2314085121. doi: 10.1073/pnas.2314085121. Epub 2024 Feb 8. Proc Natl Acad Sci U S A. 2024. PMID: 38330013 Free PMC article.
Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis.
Zhang G, Panigrahy D, Hwang SH, Yang J, Mahakian LM, Wettersten HI, Liu JY, Wang Y, Ingham ES, Tam S, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. Zhang G, et al. Among authors: hwang sh. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11127-32. doi: 10.1073/pnas.1410432111. Epub 2014 Jul 14. Proc Natl Acad Sci U S A. 2014. PMID: 25024195 Free PMC article.
Lipidomic profiling reveals soluble epoxide hydrolase as a therapeutic target of obesity-induced colonic inflammation.
Wang W, Yang J, Zhang J, Wang Y, Hwang SH, Qi W, Wan D, Kim D, Sun J, Sanidad KZ, Yang H, Park Y, Liu JY, Zhao X, Zheng X, Liu Z, Hammock BD, Zhang G. Wang W, et al. Among authors: hwang sh. Proc Natl Acad Sci U S A. 2018 May 15;115(20):5283-5288. doi: 10.1073/pnas.1721711115. Epub 2018 May 1. Proc Natl Acad Sci U S A. 2018. PMID: 29717038 Free PMC article.
Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy.
Lee KS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. Lee KS, et al. Among authors: hwang sh. J Med Chem. 2014 Aug 28;57(16):7016-30. doi: 10.1021/jm500694p. Epub 2014 Aug 11. J Med Chem. 2014. PMID: 25079952 Free PMC article.
1,535 results