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Myeloid-specific Asxl2 deletion limits diet-induced obesity by regulating energy expenditure.
Zou W, Rohatgi N, Brestoff JR, Moley JR, Li Y, Williams JW, Alippe Y, Pan H, Pietka TA, Mbalaviele G, Newberry EP, Davidson NO, Dey A, Shoghi KI, Head RD, Wickline SA, Randolph GJ, Abumrad NA, Teitelbaum SL. Zou W, et al. Among authors: brestoff jr. J Clin Invest. 2020 May 1;130(5):2644-2656. doi: 10.1172/JCI128687. J Clin Invest. 2020. PMID: 32310225 Free PMC article.
Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood.
Williams JW, Elvington A, Ivanov S, Kessler S, Luehmann H, Baba O, Saunders BT, Kim KW, Johnson MW, Craft CS, Choi JH, Sorci-Thomas MG, Zinselmeyer BH, Brestoff JR, Liu Y, Randolph GJ. Williams JW, et al. Among authors: brestoff jr. Circ Res. 2017 Sep 1;121(6):662-676. doi: 10.1161/CIRCRESAHA.117.311519. Epub 2017 Jul 10. Circ Res. 2017. PMID: 28696252 Free PMC article.
Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood.
Borcherding N, Jia W, Giwa R, Field RL, Moley JR, Kopecky BJ, Chan MM, Yang BQ, Sabio JM, Walker EC, Osorio O, Bredemeyer AL, Pietka T, Alexander-Brett J, Morley SC, Artyomov MN, Abumrad NA, Schilling J, Lavine K, Crewe C, Brestoff JR. Borcherding N, et al. Among authors: brestoff jr. Cell Metab. 2022 Oct 4;34(10):1499-1513.e8. doi: 10.1016/j.cmet.2022.08.010. Epub 2022 Sep 6. Cell Metab. 2022. PMID: 36070756 Free PMC article.
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue.
Rosina M, Ceci V, Turchi R, Chuan L, Borcherding N, Sciarretta F, Sánchez-Díaz M, Tortolici F, Karlinsey K, Chiurchiù V, Fuoco C, Giwa R, Field RL, Audano M, Arena S, Palma A, Riccio F, Shamsi F, Renzone G, Verri M, Crescenzi A, Rizza S, Faienza F, Filomeni G, Kooijman S, Rufini S, de Vries AAF, Scaloni A, Mitro N, Tseng YH, Hidalgo A, Zhou B, Brestoff JR, Aquilano K, Lettieri-Barbato D. Rosina M, et al. Cell Metab. 2022 Apr 5;34(4):533-548.e12. doi: 10.1016/j.cmet.2022.02.016. Epub 2022 Mar 18. Cell Metab. 2022. PMID: 35305295 Free PMC article.
The power and potential of mitochondria transfer.
Borcherding N, Brestoff JR. Borcherding N, et al. Among authors: brestoff jr. Nature. 2023 Nov;623(7986):283-291. doi: 10.1038/s41586-023-06537-z. Epub 2023 Nov 8. Nature. 2023. PMID: 37938702 Review.
Burning Fat to Fuel EVs.
Crewe C, Brestoff JR. Crewe C, et al. Among authors: brestoff jr. Diabetes. 2023 Nov 1;72(11):1521-1523. doi: 10.2337/dbi23-0015. Diabetes. 2023. PMID: 37862579 No abstract available.
A guide to studying mitochondria transfer.
Tiash S, Brestoff JR, Crewe C. Tiash S, et al. Among authors: brestoff jr. Nat Cell Biol. 2023 Nov;25(11):1551-1553. doi: 10.1038/s41556-023-01246-1. Nat Cell Biol. 2023. PMID: 37853133 No abstract available.
49 results