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Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Res Sq [Preprint]. 2024 Feb 23:rs.3.rs-3889456. doi: 10.21203/rs.3.rs-3889456/v1.
Res Sq. 2024.
PMID: 38464189
Free PMC article.
Updated.
Preprint.
Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Mealka M, Sierra NA, Matteo DA, Albekioni E, Khoury R, Mai T, Conley BM, Coleman NJ, Sabo KA, Komives EA, Bobkov AA, Cooksy AL, Silletti S, Schiffer JM, Huxford T, Sohl CD.
Mealka M, et al. Among authors: sierra na.
bioRxiv [Preprint]. 2024 Jan 23:2024.01.10.574970. doi: 10.1101/2024.01.10.574970.
bioRxiv. 2024.
PMID: 38260668
Free PMC article.
Updated.
Preprint.
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Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms.
Mealka M, Sierra NA, Avellaneda Matteo D, Albekioni E, Khoury R, Mai T, Conley BM, Coleman NJ, Sabo KA, Komives EA, Bobkov AA, Cooksy AL, Silletti S, Schiffer JM, Huxford T, Sohl CD.
Mealka M, et al. Among authors: sierra na.
Nat Commun. 2024 May 6;15(1):3785. doi: 10.1038/s41467-024-48277-2.
Nat Commun. 2024.
PMID: 38710674
Free PMC article.
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